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Behavioral Neurobiology Commons

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University of Massachusetts Amherst

Theses/Dissertations

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Full-Text Articles in Behavioral Neurobiology

Noradrenergic Regulation Of Decision-Making In Female And Male Rats, Emma S. Dauster Aug 2023

Noradrenergic Regulation Of Decision-Making In Female And Male Rats, Emma S. Dauster

Doctoral Dissertations

Decision-making is regulated by many associated brain regions, including the locus coeruleus (LC) and the prefrontal cortex (PFC). Disruptions in decision-making are a key feature of many disorders including attention-deficit/hyperactivity disorder which is disproportionately diagnosed in one sex over another for reasons unknown. LC or its primary neurotransmitter norepinephrine (NE) have been implicated in the etiology or treatment of disrupted decision-making. Understanding the relationship among LC, PFC, and decision-making across sexes may provide insight into the basic neurobiology of cognition and disorders that lead to disrupted decision making. There are sex differences in LC anatomy, however studies investigating sex differences …


Associations Between Anxiety And Attention In Laboratory-Housed Rhesus Macaques (Macaca Mulatta), Lauren E. Hobbs Jul 2015

Associations Between Anxiety And Attention In Laboratory-Housed Rhesus Macaques (Macaca Mulatta), Lauren E. Hobbs

Masters Theses

Previous studies completed with humans have revealed insight into the effects of anxiety on attention tasks such the dot-probe task, but there is little information about such effects on non-human primates. This study aimed to assess whether anxiety or anxious behaviors would impact rhesus macaque performance on a three stimuli paradigm similar to the dot-probe task. Utilizing images of conspecifics (strong threat, mild threat, and neutral), eight monkeys were video recorded completing a task that required them to slide two doors, which held these images, to the side to obtain a treat. We hypothesized that behavioral phenotype (high or low …