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Full-Text Articles in Behavioral Neurobiology
The Dissociation Of Location And Object Working Memory Using Fmri And Meg, Antony Passaro
The Dissociation Of Location And Object Working Memory Using Fmri And Meg, Antony Passaro
Dissertations & Theses (Open Access)
Visual working memory (VWM) involves maintaining and processing visual information, often for the purpose of making immediate decisions. Neuroimaging experiments of VWM provide evidence in support of a neural system mainly involving a fronto-parietal neuronal network, but the role of specific brain areas is less clear. A proposal that has recently generated considerable debate suggests that a dissociation of object and location VWM occurs within the prefrontal cortex, in dorsal and ventral regions, respectively. However, re-examination of the relevant literature presents a more robust distribution suggestive of a general caudal-rostral dissociation from occipital and parietal structures, caudally, to prefrontal regions, …
Cocaine Dependence: The Role Of Serotonin Genes In, Lorena Maili
Cocaine Dependence: The Role Of Serotonin Genes In, Lorena Maili
Dissertations & Theses (Open Access)
Animal studies have shown that behavioral responses to cocaine-related cues are altered by serotonergic medications. The effects of pharmacological agents on serotonin receptors 2a (5-HT2A) and 2c (5-HT2C), have yielded results suggesting that selective 5-HT2A antagonists and 5-HT2C agonists promote the disruption of cocaine-associated memories. One measure of cocaine related cues in humans is attentional bias, in which cocaine dependent individuals show greater response latency for cocaine related words than neutral words. Data from our laboratory shows that cocaine dependent subjects have altered attentional bias compared to controls. The purpose of this thesis was to investigate the role of the …