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Full-Text Articles in Behavioral Neurobiology
Contributions Of Aδ Nociceptors To The Nociceptive Withdrawal Response In Intact Unanesthetized Rats, Kristin Sammons
Contributions Of Aδ Nociceptors To The Nociceptive Withdrawal Response In Intact Unanesthetized Rats, Kristin Sammons
Senior Honors Projects, 2010-2019
The nociceptive withdrawal response (NWR), characterized by rapid withdrawal of stimulated body parts, can be evoked by stimulation of two classes of sensory nociceptors: Aδ and C-fibers. Previous studies revealed conflicting results concerning the factors that determine the direction and magnitude of the NWR. Some studies showed that the direction of the NWR depends upon stimulus location. In contrast, other studies, including those from our laboratory, showed that the direction of the NWR does not depend on stimulus location but rather is modulated by posture. However, it is likely that the heat stimuli delivered in our studies stimulated a mixture …