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Articles 1 - 10 of 10
Full-Text Articles in Behavioral Neurobiology
Neural And Behavioural Responses To Rewards And Losses In Early Development: A Functional Magnetic Resonance Imaging Study, Niki Hosseini-Kamkar
Neural And Behavioural Responses To Rewards And Losses In Early Development: A Functional Magnetic Resonance Imaging Study, Niki Hosseini-Kamkar
Electronic Thesis and Dissertation Repository
Functional magnetic resonance imaging (fMRI) was used to investigate the neural and behavioural correlates of learning from rewards and losses in children. Greater blood-oxygen-level dependent (BOLD) responses in the ventral striatum (VS) and the ventromedial prefrontal cortex (VMPFC) were found when participants received rewards compared to when they missed out on an opportunity to receive rewards. In contrast, greater BOLD responses in the anterior insula (AI) and the anterior cingulate cortex (ACC) were found when participants received losses compared to when they avoided losing. The BOLD response to rewards in the VS and VMPFC correlated positively with the tendency to …
An Analysis Of The Interaction Of Methylphenidate And Nicotine In Adolescent Rats: Effects On Bdnf, Elizabeth D. Freeman
An Analysis Of The Interaction Of Methylphenidate And Nicotine In Adolescent Rats: Effects On Bdnf, Elizabeth D. Freeman
Electronic Theses and Dissertations
This investigation was an analysis of the interaction of adolescent exposure to methylphenidate (MPH; trade name: Ritalin) on nicotine sensitization and conditioned place preference (CPP) in a rodent model and underlying mechanisms of this effect. Animals were treated IP with 1 mg/kg MPH or saline using a ―school day‖ regimen of five days on, two days off, from postnatal day (P) 28-50. During the final two weeks of MPH treatment, animals were either behaviorally sensitized to nicotine (0.5 mg/kg free base) or saline for 10 days, or conditioned to nicotine or saline using the CPP behavioral paradigm. In addition, three …
The Short And Long-Term Effects Of Chronic Ketamine During Adolescence On Object Recognition Memory In Rats, William Hardin
The Short And Long-Term Effects Of Chronic Ketamine During Adolescence On Object Recognition Memory In Rats, William Hardin
Seton Hall University Dissertations and Theses (ETDs)
Prior research has demonstrated that ketamine causes deficits in object recognition and location memory following both acute and chronic administration (Pitsikas & Boultadakis, 2009; Venãncio et al., 2011). Although it is well established that abuse of many different kinds of drugs during the critical developmental period of adolescence can lead to impairments in cognition later in adulthood (Gilpin et al., 2012; Wagner et al., 2010), no research has investigated the effects of chronic ketamine administration during adolescence and its effects on behavior in adulthood. With recent research establishing that chronic ketamine during adolescence produces late-onset alterations in electrophysiology during adulthood …
Elucidation Of Pharmacologically Manipulated Responding In The Delay Discounting Task In High Alcohol Preferring Mice, Meredith Halcomb
Elucidation Of Pharmacologically Manipulated Responding In The Delay Discounting Task In High Alcohol Preferring Mice, Meredith Halcomb
Open Access Dissertations
Impulsive behavior is the hallmark of many psychopathologies. Uncovering the neurobiological mechanisms driving impulsivity is paramount in the development of through the delay discounting (DD) task in both human and animal models. The present study is an examination of the predictive validity of the two primary types of DD procedures in animals, the Adjusting Amounts (AA) and within session Increasing Delays (ID) tasks. Methods:Subjects were administered either1.25 mg/kg d-amphetamine (AMP), 1.5 g/kg ethanol (EtOH) or saline and tested in either the AA or ID method for 15 days to evaluate drug effects on impulsive behavior. Results: Stimulant administration resulted …
Physiological And Subjective Aspects Of Positive Mood In Relation To Executive Functioning: The Potential Moderating Role Of Personality, Luz Helena Ospina
Physiological And Subjective Aspects Of Positive Mood In Relation To Executive Functioning: The Potential Moderating Role Of Personality, Luz Helena Ospina
Dissertations, Theses, and Capstone Projects
Positive affect has been demonstrated to improve aspects of cognition. However, recent studies reveal that positive affect may hinder the same cognitive processes, such as executive functioning, memory and creativity. These discrepant findings may be due to differing levels of physiological arousal, a component of the circumplex model of affect, which has been largely ignored in affective research. For example, one recent study suggests that positive valence coupled with varying levels of physiological arousal (i.e., low, moderate, and high) may differentially affect performance on tasks of verbal fluency and memory. Furthermore, one other explanation for these inconsistent findings may relate …
Relationships Between Specific Health-Related Fitness Components And Standardized Academic Achievement Tests, Tona Wilson
Relationships Between Specific Health-Related Fitness Components And Standardized Academic Achievement Tests, Tona Wilson
Walden Dissertations and Doctoral Studies
In an attempt to meet monetary-driven mandates to improve student achievement test scores, administrators are replacing physical education activities with subject matter classes in many American schools. This practice negates the positive contributions of physical activity to academic performance and student fitness. Guided by self-efficacy theory, this study assessed the impact of optimal versus minimal physical fitness state on student academic achievement. The study sample included 5,416 9th grade students from the same school district who completed a minimum of 5 of the 6 components of the FITNESSGRAM tests, and who also completed the math and English language arts (ELA) …
Differences In Stress Biomarkers In Women With High And Low Stress Appraisal, Clarissa Sara Gomez
Differences In Stress Biomarkers In Women With High And Low Stress Appraisal, Clarissa Sara Gomez
Open Access Theses & Dissertations
Measures of physiological biomarkers have been widely used in the field of stress research to explain how stress negatively impacts health outcomes. Women in particular have been shown to be more at risk for developing physiological and psychological stress-induced conditions (e.g., hypertension, depression) due to hormonal differences (Kirschbaum et al., 1992), but more importantly, because of their appraisal of stressful events (Schamus et al., 2008). Few studies however have examined whether womenâ??s stress appraisal is predictive of stress reactivity, as measured by stress biomarkers, during stressful events. The goal of this study was to examine whether stress appraisal predicted stress …
Neurotransmitter Systems And Age Related Cognitive Decline: A Focus On Attention And Plasticity, Christine Teal Kozikowski
Neurotransmitter Systems And Age Related Cognitive Decline: A Focus On Attention And Plasticity, Christine Teal Kozikowski
Dissertations, Theses, and Masters Projects
No abstract provided.
Neurocognitive Mechanisms Of Social Influence On Emotion, Emily Catherine Willroth
Neurocognitive Mechanisms Of Social Influence On Emotion, Emily Catherine Willroth
Dissertations, Theses, and Masters Projects
No abstract provided.
An Exploration Of The Wheel-Induced Feeding-Suppression, Stephen Benjamin Peckham
An Exploration Of The Wheel-Induced Feeding-Suppression, Stephen Benjamin Peckham
Theses and Dissertations (Comprehensive)
Anorexia nervosa is an enigmatic human condition typified by food-restriction that is often accompanied by extensive exercise. This has been modeled in rats in the wheel-induced feeding-suppression (WIFS) model. In this model, animals are given access to a running-wheel, which induces a volitional drop in food-consumption. Short periods of wheel access have induced a feeding-suppression which is effectively reversed by chlorpromazine administration (Adams et al., 2009). Recent attempts at replicating Adams et al.’s (2009) feeding-suppression have, however, been unsuccessful (Peckham et al., 2013). These attempts raised questions as to whether or not the existing methodology is most effective at suppressing …