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Pathogenic Microbiology Commons™

Open Access. Powered by Scholars. Published by Universities.®

2023

Biofilm

Articles 1 - 2 of 2

Full-Text Articles in Pathogenic Microbiology

Acinetobacter Baumannii - The Perfect Pathogen, Jesse Guzik, Myrna Rezcallah, Alexcia Zeller, Kaite Mattson Apr 2023

Acinetobacter Baumannii - The Perfect Pathogen, Jesse Guzik, Myrna Rezcallah, Alexcia Zeller, Kaite Mattson

Research and Scholarship Symposium Posters

Acinetobacter was discovered in 1911 by Martinus Beijerinck. Acinetobacter baumannii didn't receive its scientific name until 1986. A. baumannii is now commonly referred to as "Iraqibacter" due to a rise in infections among US military personnel returning from Iraq and Afghanistan. After the Iraq War began in 2003, the frequency of cases began to rise, especially among patients in intensive care units. Patients using ventilators, catheters, have postoperative wounds, stay in the hospital for an extended period of time, or are immunocompromised are at a considerably higher risk of getting A. baumannii. Because of its large number of virulence …

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Using Nspefs To Sensitize Mrsa To Vancomycin Treatment, Areej Malik, Alexandra E. Chittams-Miles, Claudia Muratori, Erin B. Purcell Jan 2023

Using Nspefs To Sensitize Mrsa To Vancomycin Treatment, Areej Malik, Alexandra E. Chittams-Miles, Claudia Muratori, Erin B. Purcell

The Graduate School Posters

Staphylococcus aureus (S. aureus) is a biofilm-forming pathogen. S. aureus treatment is marked by the development of antibiotic resistance. The public health impact has increased since the emergence of methicillin-resistant S. aureus (MRSA), which has started to show intermediate resistance to vancomycin in MRSA. Nano-second pulse electric fields (nsPEFs) are low-energy and high-power electric pulses, which have been suggested to sensitize pathogens to antibiotics by creating transient pores in the cell membrane. Our combinatorial treatment includes nsPEF pre-treatment and vancomycin post-treatment of MRSA cells. Our results show that MRSA log phase cells had the highest susceptibility to vancomycin. …

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