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Pathogenic Microbiology Commons

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Theses/Dissertations

2010

Bacteriophages | Bacteriophages -- Genetics | Bacteriophages -- Research -- Methodology | Antibacterial agents | Pathogenic bacteria -- Therapeutic use | Anti-infective agents | Lysine -- Derivatives

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Full-Text Articles in Pathogenic Microbiology

Phage Lysins - Structure, Genetics And Applications, Jennifer Garry Jan 2010

Phage Lysins - Structure, Genetics And Applications, Jennifer Garry

Theses

Antibiotics are of the utmost importance in the fight against pathogenic bacteria, however, in recent years there has been a continual increase in the development of antibiotic resistance among bacteria. As a result it has become essential to develop new technologies to combat these pathogens. One such technology is the application of phage lysins as antimicrobial agents against pathogenic infections. A promising phage lysin is LysK, a 495 amino-acid protein derived from Staphylococcal Phage K. LysK can lyse a wide range of staphylococcal species including MRSA. It is also capable of killing both live and dead cells increasing its potential …