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Articles 1 - 2 of 2
Full-Text Articles in Pathogenic Microbiology
Host Pathogen Interactions: Is Arabidopsis Thaliana Remembered By Its Nemesis Pseudomonas Syringae?, Daniel Z. Kreiser
Host Pathogen Interactions: Is Arabidopsis Thaliana Remembered By Its Nemesis Pseudomonas Syringae?, Daniel Z. Kreiser
Lawrence University Honors Projects
Plants contain innate immune systems that deter pathogen infection. Pattern recognition receptors bind microbe-associated molecular patterns (MAMPs), triggering immunity. MAMPs are proteins exclusive to pathogens that are typically indispensable for their survival. For this reason, MAMPs cannot be mutated or removed without causing pathogen death. However, this does not necessitate constitutive expression of MAMPs. In this study, the MAMP response of Arabidopsis thaliana was utilized to determine differential detection of MAMPs expressed by Pseudomonas syringe pv. tomato DC3000 when pretreated with A. thaliana. Results demonstrated that more MAMPs are detected when P. syringae had previously encountered A. thaliana, …
Discovery Of A Novel Antibiotic From A Bacillus Bacterium Cultivated From Its Natural Environment, Patrick J. Mcmonagle
Discovery Of A Novel Antibiotic From A Bacillus Bacterium Cultivated From Its Natural Environment, Patrick J. Mcmonagle
Lawrence University Honors Projects
The current primary method of treating bacterial infections is using antibiotics. However, this continued treatment of these illnesses caused by pathogenic bacteria is causing the rate of evolution of these disease-inducing organisms to increase. Antibiotic resistance is forcing scientists to search for new forms of antibiotics to compete with these new ‘super bugs.’ I pursued the search for novel antibiotics through their natural source – antibiotic-producing microorganisms. As microbes have a direct advantage when producing antibiotics, it is my thought that they will be the best resource to discovering new and effective antibiotics. I conducted an exploratory search for antibiotic-producing …