Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 1 of 1
Full-Text Articles in Pathogenic Microbiology
Characterization Of Spy1600 A Putative Hyaluronidase Gene In Group A Streptococci, Karin M. Berling
Characterization Of Spy1600 A Putative Hyaluronidase Gene In Group A Streptococci, Karin M. Berling
Biological Sciences Theses & Dissertations
Group A Streptococci (GAS), also known as Streptococcus pyogenes, can cause a variety of human diseases ranging from asymptomatic to life threatening. Exactly how a single type of organism is able to inflict such a multitude of diseases remains to be fully understood. One possibility includes the large number of secreted virulence factors expressed by the organism. The recent sequencing of three streptococcal genomes has indicated the existence of several previously unknown genes, some of which may encode possible virulence factors. Among these is Spy1600, which based on its sequence similarities has been proposed to encode a hyaluronidase, a …