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Full-Text Articles in Microbiology
Influence Of Epstein-Barr Virus On Systemic Lupus Erythematosus Disease Development And The Role Of Depression On Disease Progression, Caleb Cornaby
Influence Of Epstein-Barr Virus On Systemic Lupus Erythematosus Disease Development And The Role Of Depression On Disease Progression, Caleb Cornaby
Theses and Dissertations
Systemic Lupus Erythematosus (SLE) is an autoimmune disease affecting 20 to 250 individuals per 100,000 worldwide. Symptomology includes dermatological manifestations such as discoid lesions, acute cutaneous rashes, and oral and nasal ulcers, along with musculoskeletal, pulmonary, and renal complications. Abnormal T and B lymphocyte function and apoptosis, immune complex clearance, complement function, and nucleosome processing are typical of disease pathophysiology. SLE is the result of both environmental and genetic factors, which together create the conditions leading to disease onset and progression. Of these environmental factors, Epstein-Barr virus (EBV) infection is known to cause the genesis of cross-reactive antibodies in SLE …
Analysis Of Anti-Dengue Antibodies, Lauren Syndergaard, Brian Poole
Analysis Of Anti-Dengue Antibodies, Lauren Syndergaard, Brian Poole
Journal of Undergraduate Research
Dengue virus is a mosquitoes-borne virus that causes dengue fever. It is found primarily in tropical areas with over a third of the world’s population living in at-risk areas (WHO). The number of infections has grown rapidly in recent years with as many as 50 to 100 million infections occur each year (WHO). Though not widely present in the United States (small outbreaks occur with some regularity in Texas from the Mexican border; Hawaii and Florida relatively recently had cases), many travelers endemic areas contract the virus. Though several are being studied, as yet, there are no vaccines available for …
Effect Of Ebi2 On B Cell Migration, Jeffrey Mella, Brian Poole
Effect Of Ebi2 On B Cell Migration, Jeffrey Mella, Brian Poole
Journal of Undergraduate Research
My mentored research project was a terrific experience. I have been mentored with Dr. Brian Poole for the last three years. As a result of the project that was made possible by the ORCA grant, I was the first author on an abstract submitted and accepted by the International Immunology Summit. This last October I attended the International Immunology Summit in Las Vegas, Nevada. Dr. Poole and I presented our research and I responded to questions from the audience. I am currently an author on a manuscript that in progress that has been submitted for review. I have enjoyed my …