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Microbiology Commons

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Full-Text Articles in Microbiology

Discovery Of Geographical Gene Variants In Related Pseudomonas Aeruginosa Bacteriophages, Emilee Carr, Elise Melhado, Emily Loertscher, Trever Thurgood, Ruchira Sharma, Julianne H. Grose Apr 2018

Discovery Of Geographical Gene Variants In Related Pseudomonas Aeruginosa Bacteriophages, Emilee Carr, Elise Melhado, Emily Loertscher, Trever Thurgood, Ruchira Sharma, Julianne H. Grose

Library/Life Sciences Undergraduate Poster Competition 2019

Antibiotic resistant bacterial strains are a major crisis in the world due to the difficult nature of curing individuals afflicted with them. Phage therapy has been proposed as an alternate treatment for these bacterium. In Dr. Julianne Grose's lab, bacteriophages were against the bacteria, Pseudomonas aeruginosa. To isolate, environmental samples were utilized in enrichment cultures that were ultimately used in serial dilutions, plaque purification, electron microscopy, DNA isolation, sequencing, and genome annotation. The P. aeruginosa phage, TF17, infects a bacterial strain that is highly related to a strain that causes fatalities as an opportunistic infection in patients with cystic fibrosis. …


High Salinity Stabilizes Bacterial Community Composition And Activity Through Time, Tylan Wayne Magnusson Jun 2015

High Salinity Stabilizes Bacterial Community Composition And Activity Through Time, Tylan Wayne Magnusson

Theses and Dissertations

Dormancy is a plausible strategy for bacteria to overcome the effects of temporal fluctuations in resources or stresses and await more “optimal” conditions to resume metabolic activity and growth. Seasonal changes in environmental conditions force microbes to adjust their metabolic activity accordingly, and community composition drastically shifts. In extreme environments, however, the overriding effects of a constant stress may constrain the need or benefit of bacteria entering dormancy. In hypersaline lakes, high metabolic activity is required to maintain adaptations that permit survival. Sampling from six lakes on a salinity gradient (0.05% – 30.3%), we measured seasonal fluctuations in bacterial dormancy …


Hypersaline Lake Environments Exhibit Reduced Microbial Dormancy, Joshua Christopher Vert Jun 2013

Hypersaline Lake Environments Exhibit Reduced Microbial Dormancy, Joshua Christopher Vert

Theses and Dissertations

From acid seeps and deep-sea thermal vents to glacial ice and hypersaline lakes, extreme environments contain relatively simplified communities consisting of extremophiles that have evolved to survive and thrive under adverse abiotic conditions. In more neutral environments, microorganisms use dormancy as a common life history strategy to weather temporal fluctuations of resources or stresses until more 'optimal' conditions are present. It is unclear if dormancy is an essential survival mechanism for microorganisms in extreme environments; however, recent studies suggest that extreme environments may create stable conditions for extremophiles to the extent that dormancy is of less ecological importance. Using lake …