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Full-Text Articles in Biomechanics
Modulation Of Cell-Matrix Interaction For Cryopreservation Of Engineered Tissue, Angela Christine Seawright
Modulation Of Cell-Matrix Interaction For Cryopreservation Of Engineered Tissue, Angela Christine Seawright
Open Access Theses
Long term preservation of functional engineered tissues can significantly advance tissue engineering industry and regenerative medicine. Several preservation techniques have been proposed and investigated for this purpose, and cryopreservation is a leading candidate. While tissues are cryopreserved, ice forms in both the extracellular and intracellular spaces and causes freezing-induced spatiotemporal deformation of the tissue. During this process the cells undergo dehydration by the freezing-induced osmotic pressure difference and mechanical deformation, transmitted through cell-extracellular matrix adhesions. However, the significance and interaction of these cellular level transport and mechanics processes are not well understood. Therefore, this study aims to establish mechanistic understanding …
Modeling Of Legged Locomotion With A Suspended Load In The Sagittal Plane, Karna P. Potwar
Modeling Of Legged Locomotion With A Suspended Load In The Sagittal Plane, Karna P. Potwar
Open Access Theses
Walking or running while carrying loads has always been a tedious task, more so when the loads are heavy. Such a task of carrying loads not only requires extra effort but also leads to physical pain and in some cases injury. Prior studies on human locomotion with a suspended load have used models that are restricted in their DOFs and so are not able to take into account the fore aft movement in human beings. The objective of this thesis is to model the dynamics of sagittal plane center-of-mass locomotion with a suspended load and apply findings to carrying loads …