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Discovering Motor Phenotypes In Autism Spectrum Disorder: A Cross-Syndrome Approach, Daniel Edwin Lidstone
Discovering Motor Phenotypes In Autism Spectrum Disorder: A Cross-Syndrome Approach, Daniel Edwin Lidstone
UNLV Theses, Dissertations, Professional Papers, and Capstones
Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder with a behavioral phenotype characterized by persistent deficits in social communication and social interaction accompanied by restricted, repetitive patterns of behaviors, interests, or activities. Currently in the US, approximately 2.5% of children have a diagnosis of ASD. The etiology of ASD is complex, however the disorder does have a strong genetic basis. Specific genetic mutations can lead to neuroanatomical and neurophysiological changes during development resulting in a behavioral phenotype that falls along the ASD spectrum and may result in a diagnosis of ASD. The severity of ASD-specific behaviors falls on a continuum …