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Biomechanics Commons

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Full-Text Articles in Biomechanics

Ampk Activation: A Therapeutic Target For Type 2 Diabetes?, Kimberly A. Coughlan, Rudy Valentine, Neil B. Ruderman, Asish K. Saha Jun 2014

Ampk Activation: A Therapeutic Target For Type 2 Diabetes?, Kimberly A. Coughlan, Rudy Valentine, Neil B. Ruderman, Asish K. Saha

Rudy Valentine

Type 2 diabetes (T2D) is a metabolic disease characterized by insulin resistance, β-cell dysfunction, and elevated hepatic glucose output. Over 350 million people worldwide have T2D, and the International Diabetes Federation projects that this number will increase to nearly 600 million by 2035. There is a great need for more effective treatments for maintaining glucose homeostasis and improving insulin sensitivity. AMP-activated protein kinase (AMPK) is an evolutionarily conserved serine/threonine kinase whose activation elicits insulin-sensitizing
effects, making it an ideal therapeutic target for T2D. AMPK is an energy-sensing enzyme that is activated when cellular energy levels are low, and it signals …


Gait Initiation Mechanics In Concussed Varsity Athletes, Adam Harper Jan 2014

Gait Initiation Mechanics In Concussed Varsity Athletes, Adam Harper

Theses and Dissertations (Comprehensive)

Concussions are a common and potentially serious injury that affects athletes across multiple sports. More than ever concussions are now at the forefront of sport-related research.

Current research indicates that in a cohort of Canadian junior hockey players examined during the 2009-2010 season showed a rate of concussion at 36.5% of all athletic injuries (Echlin et al., 2010). This rate of concussion injury indicates that proper evaluations and examination tools are key to successful management of concussions. The objective of this study was to determine whether a functional task such as gait initiation is able to quantify stability difference following …


Training Strategies And Movement Assessments In Athletes And Non-Athletes, Matthew David Lewis Jan 2014

Training Strategies And Movement Assessments In Athletes And Non-Athletes, Matthew David Lewis

Theses and Dissertations--Kinesiology and Health Promotion

This dissertation is composed of three manuscripts based on two studies related to training and assessment methods used to evaluate change and overall quality in measures of performance, postural control, and functional movement. Study one evaluated the effect of sand training on athletic performance and postural control. Study two investigated the effect of scoring strata of the deep squat (DS) component of the Functional Movement Screen (FMS) on the weight-bearing lunge test (WBLT), Star Excursion Balance Test (SEBT), and Lateral Flexion Test (LFT) in 101 male and female college students.

Study one results included significant overall improvements of the five …