Open Access. Powered by Scholars. Published by Universities.®
- Institution
- Keyword
-
- Biomechanics (4)
- Daniel Felix Ritchie School of Engineering and Computer Science (3)
- Mechanical and Materials Engineering (3)
- Kinematics (2)
- Musculoskeletal modeling (2)
-
- AGING (1)
- Anti-gravity treadmill (1)
- Arthroplasty (1)
- Augmented feedback (1)
- Axle position (1)
- BIOMECHANICS (1)
- BONE (1)
- Blueberry harvesting (1)
- CT-Scan (1)
- Center of pressure (1)
- Chronotherapy (1)
- Circadian Rhythms (1)
- Contact forces (1)
- Effective force (1)
- Elastic Fibers (1)
- Elastin (1)
- Fall risk (1)
- Finite element (1)
- Fluoroscopy (1)
- Foot contact dynamics (1)
- Foot initial contact (1)
- Footwear (1)
- Gait analysis (1)
- Gait characteristics (1)
- Gene Therapy (1)
- Publication
- Publication Type
Articles 1 - 17 of 17
Full-Text Articles in Biomechanics
Defining The Role Of Elastic Fibers In Tendon Mechanics, Jeremy D. Eekhoff
Defining The Role Of Elastic Fibers In Tendon Mechanics, Jeremy D. Eekhoff
McKelvey School of Engineering Theses & Dissertations
Tendons serve as a linking component of the musculoskeletal system by transferring forces between muscle and bone. As such, the structural proteins of the tendon extracellular matrix are of vital importance for the tissue to function properly and maintain its mechanical integrity. Collagen is the principal constituent of tendon and makes up its aligned hierarchical organization. Other structural proteins, such as elastin, are in comparison understudied and not well understood in relation to tendon function. Elastin, the main component of elastic fibers, has unique mechanical properties including high extensibility, fatigue resistance, and elasticity; these properties are important for elastin-rich tissues …
Effects Of Seat And Axle Position On Pain, Pathology, And Independence In Pediatric Manual Wheelchair Users With Spinal Cord Injury, Hannah Frank
Theses and Dissertations
Manual wheelchair (MWC) users with spinal cord injury (SCI) rely heavily on their upperextremities to complete daily occupations. Due to repetitive shoulder use during wheelchair mobility and propulsion, MWC users are at greater risk of shoulder pain and shoulder pathology, and thus decreased independence, and lower quality of life. The relative fit of the wheelchair and its parameters are critical and can further impact the user’s propulsion biomechanics. Parameters such as seat angle and axle position may put the user in detrimental shoulder positions for longer periods of time, impacting health outcomes even more. Although the effects of wheelchair setup …
Use Of Pressure-Measuring Insoles To Characterize Gait Parameters In Simulated Reduced-Gravity Conditions, Christian Ison, Connor Neilsen, Jessica Deberardinis, Mohamed B. Trabia, Janet S. Dufek
Use Of Pressure-Measuring Insoles To Characterize Gait Parameters In Simulated Reduced-Gravity Conditions, Christian Ison, Connor Neilsen, Jessica Deberardinis, Mohamed B. Trabia, Janet S. Dufek
Mechanical Engineering Faculty Research
Prior researchers have observed the effect of simulated reduced-gravity exercise. However, the extent to which lower-body positive-pressure treadmill (LBPPT) walking alters kinematic gait characteristics is not well understood. The purpose of the study was to investigate the effect of LBPPT walking on selected gait parameters in simulated reduced-gravity conditions. Twenty-nine college-aged volunteers participated in this cross-sectional study. Participants wore pressure-measuring insoles (Medilogic GmBH, Schönefeld, Germany) and completed three 3.5-min walking trials on the LBPPT (AlterG, Inc., Fremont, CA, USA) at 100% (normal gravity) as well as reduced-gravity conditions of 40% and 20% body weight (BW). The resulting insole data were …
Development Of A Novel Haptic Feedback System For Gait Training Applications, Mohsen Alizadeh Noghani
Development Of A Novel Haptic Feedback System For Gait Training Applications, Mohsen Alizadeh Noghani
Electronic Theses and Dissertations
Until recently, study and correction of motor or gait functions required costly sensors and measurement setups (e.g., optical motion capture systems) which were only available in laboratories or clinical environments. However, due to (1) the growing availability and affordability of inertial measurement units (IMUs) with high accuracy, and (2) progress in wireless, high bandwidth, and energy-efficient networking technologies such as Bluetooth Low Energy (BLE), it is now possible to measure and provide feedback in real-time for biomechanical parameters outside of those specialized settings. To enable gait training without an expert who can provide verbal feedback, augmented feedback, which is divided …
A Systematic Review And Meta-Analysis On The Efficacy Of Stem Cell Therapy On Bone Brittleness In Mouse Models Of Osteogenesis Imperfecta, Lauren Battle, Shoshana Yakar, Alessandra Carriero
A Systematic Review And Meta-Analysis On The Efficacy Of Stem Cell Therapy On Bone Brittleness In Mouse Models Of Osteogenesis Imperfecta, Lauren Battle, Shoshana Yakar, Alessandra Carriero
Publications and Research
There is no cure for osteogenesis imperfecta (OI), and current treatments can only partially correct the bone phenotype. Stem cell therapy holds potential to improve bone quality and quantity in OI. Here, we conduct a systematic review and meta-analysis of published studies to investigate the efficacy of stem cell therapy to rescue bone brittleness in mouse models of OI. Identified studies included bone marrow, mesenchymal stem cells, and human fetal stem cells. Effect size of fracture incidence, maximum load, stiffness, cortical thickness, bone volume fraction, and raw engraftment rates were pooled in a random-effects meta-analysis. Cell type, cell number, injection …
Development And Evaluation Of An Attachable Anti-Vibration Handle For Blueberry Hand Shaker, Jashwant Thota
Development And Evaluation Of An Attachable Anti-Vibration Handle For Blueberry Hand Shaker, Jashwant Thota
Electronic Theses and Dissertations
Blueberry production has skyrocketed in the past two decades due to an exponential increase in consumer demand around the world. The harvesting of fresh, high-quality blueberries requires extensive care. Large-scale automatic harvesters damage the fruit and make it unsuitable for storage and transportation, which requires more than two weeks to complete. Therefore, hand harvesters are used, avoiding damage to the fruit, and increasing harvesting efficiency multifold when compared with that of hand-picking. The downside of these hand harvesters is their high Hand Arm Vibration (HAV), which is very dangerous for the worker and can cause hand-arm vibration syndrome (HAVS). This …
Synthetic Gene Circuits For Self-Regulating And Temporal Delivery Of Anti-Inflammatory Biologic Drugs In Engineered Tissues, Lara Pferdehirt
Synthetic Gene Circuits For Self-Regulating And Temporal Delivery Of Anti-Inflammatory Biologic Drugs In Engineered Tissues, Lara Pferdehirt
McKelvey School of Engineering Theses & Dissertations
The recent advances in the fields of synthetic biology and genome engineering open up new possibilities for creating cell-based therapies. We combined these tools to target repair of articular cartilage, a tissue that lacks a natural ability to regenerate, in the presence of arthritic diseases. To this end, we developed cell-based therapies that harness disease pathways and the unique properties of articular cartilage for prescribed, localized, and controlled delivery of biologics, creating the next generation of cell therapies and new classes of synthetic circuits. We created tissue engineered cartilage from murine induced pluripotent stem cells that had the ability to …
Subject-Specific Musculoskeletal Modeling Of Hip Dysplasia Biomechanics, Ke Song
Subject-Specific Musculoskeletal Modeling Of Hip Dysplasia Biomechanics, Ke Song
McKelvey School of Engineering Theses & Dissertations
Developmental dysplasia of the hip (DDH) is characterized by abnormal bony anatomy, causes pain and functional limitations, and is a prominent risk factor for premature hip osteoarthritis. Although the pathology of DDH is believed to be mechanically-induced, little is known about how DDH anatomy alters hip biomechanics during activities of daily living, partly due to the difficulties with measuring hip muscle and joint forces. Musculoskeletal models (MSMs) are useful for dynamic simulations of joint mechanics, but the reliability of MSMs for DDH research is limited by an accurate model representation of the unique hip anatomy. To address such challenges, this …
Patient-Specific Finite Element Analysis For Mandibular Fracture Fixation, Ethan Snyder
Patient-Specific Finite Element Analysis For Mandibular Fracture Fixation, Ethan Snyder
UNLV Theses, Dissertations, Professional Papers, and Capstones
This thesis proposes an approach for Finite Element Analysis (FEA) of mandibular fracture fixation. Using a Computerized Tomography (CT) scan of mandible obtained from a specific person, the material characteristics, density and modulus of elasticity, were determined from a set of discrete points within the mandible that are 1mm spaced based on the Hounsfield Units of these points. The mandible geometry was sectioned to simulate a fracture. Muscle and mastication forces were added to replicate post-surgery loading. Using a standard linear miniplate, this material model was compared with two commonly used mandibular cortical shell bone models: isotropic and orthotropic. A …
Musculoskeletal Modeling Of The Pelvis And Lumbar Spine During Running, Ruth Higgins, Maryam Moeini, Hunter Bennett, Stacie Ringleb
Musculoskeletal Modeling Of The Pelvis And Lumbar Spine During Running, Ruth Higgins, Maryam Moeini, Hunter Bennett, Stacie Ringleb
College of Engineering & Technology (Batten) Posters
Musculoskeletal modeling provides an alternative to in-vivo characteristics that are difficult to directly measure for movements such as running, especially for trunk muscles and joints. The full-body-lumbar-spine (FBLS) model by Raabe and Chaudhari, 2016 is an OpenSim model created for simulations of jogging. The lifting full-body (LFB) model by Beaucage-Gauvreau et al., 2018 is an adaptation of the FBLS created for estimating spinal loads during lifting. PURPOSE: Determine validity of the FBLS and LFB models in simulating pelvis and lumbar spine kinematics during running. METHODS: Inverse Kinematics were executed using experimental data for the FBLS and LFB models. To …
Predictions Of Knee Joint Contact Forces Using Only Kinematic Inputs With A Recurrent Neural Network, Kaileigh Elisabeth Estler
Predictions Of Knee Joint Contact Forces Using Only Kinematic Inputs With A Recurrent Neural Network, Kaileigh Elisabeth Estler
Human Movement Sciences Theses & Dissertations
BACKGROUND: Knee joint contact (bone on bone) forces are commonly estimated using surrogate measures such as external knee adduction moments (with limited success) or musculoskeletal modeling (more successful). Despite its capabilities, modeling is not optimal for clinicians or persons with limited experience and knowledge. Therefore, the purpose of this study was to design a novel prediction method for knee joint contact forces that is equal or more accurate than modeling, yet simplistic in terms of required inputs. METHODS: This study included all six subjects’ (71.3±6.5kg, 1.7±0.1m) data from the opensource “Grand Challenge” datasets (simtk.org) and two subjects from the "CAMS" …
Foot Contact Dynamics And Fall Risk Among Children Diagnosed With Idiopathic Toe Walking, Rahul Soangra, Michael Shiraishi, Richard Beuttler, Michelle Gwerder, Lou Anne Boyd, Venkatesan Muthukumar, Mohamed Trabia, Afshin Aminian, Marybeth Grant-Beuttler
Foot Contact Dynamics And Fall Risk Among Children Diagnosed With Idiopathic Toe Walking, Rahul Soangra, Michael Shiraishi, Richard Beuttler, Michelle Gwerder, Lou Anne Boyd, Venkatesan Muthukumar, Mohamed Trabia, Afshin Aminian, Marybeth Grant-Beuttler
Electrical & Computer Engineering Faculty Research
Children that are diagnosed with Idiopathic Toe walking (cITW) are characterized by persistent toe-to-toe contacts. The objective of this study was to explore whether typical foot contact dynamics during walking predisposes cITW to a higher risk of falling. Twenty cITW and age-matched controls performed typical and toe walking trials. The gait parameters related to foot contact dynamics, vertical force impulses during stance, slip, and trip risk were compared for both groups. We found that cITW manifest less stable gait and produced significantly higher force impulses during push-off. Additionally, we found that cITW had a higher slip-initiation risk that was associated …
Biomechanics Of Trail Running Performance: Quantification Of Spatio-Temporal Parameters By Using Low Cost Sensors In Ecological Conditions, Noé Perrotin, Nicolas Gardan, Arnaud Lesprillier, Clément Le Goff, Jean-Marc Seigneur, Ellie Abdi, Borja Sanudo, Redha Taiar
Biomechanics Of Trail Running Performance: Quantification Of Spatio-Temporal Parameters By Using Low Cost Sensors In Ecological Conditions, Noé Perrotin, Nicolas Gardan, Arnaud Lesprillier, Clément Le Goff, Jean-Marc Seigneur, Ellie Abdi, Borja Sanudo, Redha Taiar
Publications
The recent popularity of trail running and the use of portable sensors capable of measuring many performance results have led to the growth of new fields in sports science experimentation. Trail running is a challenging sport; it usually involves running uphill, which is physically demanding and therefore requires adaptation to the running style. The main objectives of this study were initially to use three “low-cost” sensors. These low-cost sensors can be acquired by most sports practitioners or trainers. In the second step, measurements were taken in ecological conditions orderly to expose the runners to a real trail course. Furthermore, to …
Age And Sex Differences In Load-Induced Tibial Cortical Bone Surface Strain Maps, Alessandra Carriero, Behzad Javaheri, Neda Bassir Kazeruni, Andrew A. Pitsillides, Sandra J. Shefelbine
Age And Sex Differences In Load-Induced Tibial Cortical Bone Surface Strain Maps, Alessandra Carriero, Behzad Javaheri, Neda Bassir Kazeruni, Andrew A. Pitsillides, Sandra J. Shefelbine
Publications and Research
Bone adapts its architecture to the applied load; however, it is still unclear how bone mechano-adaptation is coordinated and why potential for adaptation adjusts during the life course. Previous animal models have suggested strain as the mechanical stimulus for bone adaptation, but yet it is unknown how mouse cortical bone load-related strains vary with age and sex. In this study, full-field strain maps (at 1 N increments up to 12 N) on the bone surface were measured in young, adult, and old (aged 10, 22 weeks, and 20 months, respectively), male and female C57BL/6J mice with load applied using a …
Tibial Strains And Tray-Bone Micromotions After Total Knee Arthroplasty: Computational Studies Evaluating The Tibial Fixation, Huizhou Yang
Tibial Strains And Tray-Bone Micromotions After Total Knee Arthroplasty: Computational Studies Evaluating The Tibial Fixation, Huizhou Yang
Electronic Theses and Dissertations
Cemented and cementless fixation in total knee arthroplasty (TKA) have been successfully used for decades. As the number of younger and more active patients treated with TKA continues to increase, long-term implant survivorship is of increasing importance. One of the most common complications and hence the reason for revision is mechanical loosening (23.1% of all revised TKA). The loosening mechanisms have been proposed for different fixation types. For cemented fixation, bone remodeling after surgery is regulated by the changes in strain energy density (SED). The recruitment of osteoclasts and osteoblasts is controlled by SED-related signals. Insufficient stimuli can promote bone …
Accurate Measurement Of Healthy Joint Kinematics To Inform Diagnosis And Treatment, Vasiliki Kefala
Accurate Measurement Of Healthy Joint Kinematics To Inform Diagnosis And Treatment, Vasiliki Kefala
Electronic Theses and Dissertations
The description of human motion has a primary importance in different scientific areas such as medicine, sports, physical therapy. Kinematics specifically studies pure motion without reference to the causes of motion such as forces. Understanding the kinematics of human movement is of critical importance in medicine and biology. Motion measurement can be used in order to to evaluate functional performance of limbs under normal and abnormal conditions. Kinematic knowledge is also important for diagnosis and surgical treatment of joint disease and the design of implants to rehabilitate function. Accurate joint kinematics is essential to protect articular functionality. An alteration may …
Broadening The Capability Of Kinetics Analysis In Biomechanics, Nicholas Nelson
Broadening The Capability Of Kinetics Analysis In Biomechanics, Nicholas Nelson
Electronic Theses and Dissertations
Two studies are discussed in this manuscript each preceded by a literature review of the topic. The first review and study explore agility movements and the effect that alternative upper designs in shoes might have on ground reaction force measures of performance. The second review and study evaluate methods of predicting ground reaction forces without the use of a force platform. A method of using effective forces and ways of improving its accuracy are evaluated in depth.