Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 1 of 1
Full-Text Articles in Biomechanics
Development Of Functional Interactions Among Cortical And Trabecular Traits During Growth Of The Lumbar Vertebral Body, Melissa Ramcharan
Development Of Functional Interactions Among Cortical And Trabecular Traits During Growth Of The Lumbar Vertebral Body, Melissa Ramcharan
Dissertations, Theses, and Capstone Projects
Variation in bone traits that contribute to increased fracture risk in the elderly is mainly established in adulthood. Previous studies have shown that in adults, cortical and trabecular traits are functionally related. How variations in traits develop to establish mechanical function in adult bone is not well understood. In this study, we examined temporal changes in the development of cortical and trabecular traits during growth in mouse lumbar vertebral body structures that have a wide range of genetic variants. We determined a sequence of events among traits that would suggest how functional bone structures developed. Examining bones in A/J, C57/BL6 …