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Genomics Commons

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Selected Works

2004

Articles 1 - 2 of 2

Full-Text Articles in Genomics

Heterogeneous Evolutionary Processes Affect R Gene Diversity In Natural Populations Of Solanum Pimpinellifolium, Ana Lucia Caicedo, B. A. Schaal Jan 2004

Heterogeneous Evolutionary Processes Affect R Gene Diversity In Natural Populations Of Solanum Pimpinellifolium, Ana Lucia Caicedo, B. A. Schaal

Ana Lucia Caicedo

Resistance (R) genes of plants are responsible for pathogen recognition and encode proteins that trigger a cascade of responses when a pathogen invades a plant. R genes are assumed to be under strong selection, but there is limited knowledge of the processes affecting R gene diversity in the wild. In this study, DNA sequence variation of Cf-2 homologs was surveyed in populations of Solanum pimpinellifolium, a wild relative of the cultivated tomato. The Cf-2 locus is involved in resistance to strains of the fungus Cladosporium fulvum. At least 26 different Cf-2 homologs were detected in natural populations of S. pimpinellifolium. …


Epistatic Interaction Between The Arabidopsis Fri And Flc Flowering Time Genes Generates A Latitudinal Cline In A Life History Trait, Ana Lucia Caicedo, J. R. Stinchcombe, K. M. Olsen, J Schmitt, M. D. Purugganan Jan 2004

Epistatic Interaction Between The Arabidopsis Fri And Flc Flowering Time Genes Generates A Latitudinal Cline In A Life History Trait, Ana Lucia Caicedo, J. R. Stinchcombe, K. M. Olsen, J Schmitt, M. D. Purugganan

Ana Lucia Caicedo

Epistatic gene interactions are believed to be a major factor in the genetic architecture of evolutionary diversification. In Arabidopsis thaliana, the FRI and FLC genes mechanistically interact to control flowering time, and here we show that this epistatic interaction also contributes to a latitudinal cline in this life history trait within the species. Two major FLC haplogroups (FLCA and FLCB ) are associated with flowering time variation in A. thaliana in field conditions, but only in the presence of putatively functional FRI alleles. Significant differences in latitudinal distribution of FLC haplogroups in Eurasia and North Africa also depend on the …