Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Computational Biology (10)
- Bioinformatics (9)
- Microbiology (8)
- Molecular Genetics (6)
- Other Genetics and Genomics (5)
-
- Biology (3)
- Biotechnology (3)
- Entomology (2)
- Genetics (2)
- Medicine and Health Sciences (2)
- Agriculture (1)
- Animal Diseases (1)
- Animal Sciences (1)
- Biochemistry (1)
- Biochemistry, Biophysics, and Structural Biology (1)
- Cell and Developmental Biology (1)
- Developmental Biology (1)
- Diseases (1)
- Ecology and Evolutionary Biology (1)
- Evolution (1)
- Food and Drug Law (1)
- Health Law and Policy (1)
- Law (1)
- Medical Sciences (1)
- Molecular Biology (1)
- Poultry or Avian Science (1)
- Veterinary Infectious Diseases (1)
- Keyword
-
- 3’UTR (1)
- Ephemeroptera (1)
- Food and Drug Law (1)
- Health Law and Policy (1)
- Insect Systematics (1)
-
- Law and Technology (1)
- Medical Jurisprudence (1)
- MicroRNA (1)
- Phylogenetics (1)
- RNA-binding protein (1)
- RNAi (1)
- Science and Technology (1)
- Sequence Alignment and Phylogenetics (1)
- Stau-1 (1)
- [Bayesian; maximum likelihood; maximum parsimony; multiple sequence alignment; neighbor joining; phylogenetics; simulation; tree reconstruction (1)
Articles 1 - 13 of 13
Full-Text Articles in Genomics
Staufen Negatively Modulates Microrna Activity In Caenorhabditis Elegans, Zhiji Ren, Isana Veksler-Lublinsky, David Morrissey, Victor Ambros
Staufen Negatively Modulates Microrna Activity In Caenorhabditis Elegans, Zhiji Ren, Isana Veksler-Lublinsky, David Morrissey, Victor Ambros
Victor R. Ambros
The double-stranded RNA-binding protein Staufen has been implicated in various post-transcriptional gene regulatory processes. Here we demonstrate that the Caenorhabditis elegans homolog of Staufen, STAU-1, functionally interacts with microRNAs. Loss-of-function mutations of stau-1 significantly suppress phenotypes of let-7 family microRNA mutants, a hypomorphic allele of dicer and a lsy-6 microRNA partial loss-of-function mutant. Furthermore, STAU-1 modulates the activity of lin-14, a target of lin-4 and let-7 family microRNAs, and this modulation is abolished when the 3' untranslated region of lin-14 is removed. Deep sequencing of small RNA cDNA libraries reveals no dramatic change in the levels of microRNAs, or other …
Variation In Avian Pathogenic Escherichia Coli Colonization Levels In Chickens, Melissa Monson, Michael Kaiser, Susan Lamont
Variation In Avian Pathogenic Escherichia Coli Colonization Levels In Chickens, Melissa Monson, Michael Kaiser, Susan Lamont
Melissa Monson
Colonization levels in five tissues after avian pathogenic Escherichia coli (APEC) inoculation were investigated in chickens to generate phenotypic data for a genome wide association study (GWAS). Bacterial loads were measured in 370 birds and varied among individuals and tissues. Mean bacterial levels were significantly different between tissues (right lung > spleen > left lung and liver > blood). There were also significant correlations in bacterial load between tissues. These data suggest that colonization levels could be used as phenotypes in GWAS and could help identify markers associated with poultry resistance to APEC infections. After verification, these markers could be used for genetic …
Inhibition Of Herpes Simplex Virus Type 1 With The Modified Green Tea Polyphenol Pamitoyl-Epigallocatechin Gallate., Aline De Oliveira, Sandra Adams, Lee Lee, Sean Murray, Stephen Hsu, Jeffrey Hammond, Douglas Dickinson, Ping Chen, Tin-Chun Chu
Inhibition Of Herpes Simplex Virus Type 1 With The Modified Green Tea Polyphenol Pamitoyl-Epigallocatechin Gallate., Aline De Oliveira, Sandra Adams, Lee Lee, Sean Murray, Stephen Hsu, Jeffrey Hammond, Douglas Dickinson, Ping Chen, Tin-Chun Chu
Tin-Chun Chu, Ph.D.
No abstract provided.
Epigallocatechin-3-Gallate Modulates Oxidative Stress In Exocrine Glands Of A Primary Sjogren’S Syndrome Mouse Model Prior To Disease Onset, Seiji Ohno, Hongfang Yu, Douglas Dickinson, Tin-Chun Chu, Kalu Ogbureke, Scott Derossi, Tetsuya Yamamoto, Stephen Hsu
Epigallocatechin-3-Gallate Modulates Oxidative Stress In Exocrine Glands Of A Primary Sjogren’S Syndrome Mouse Model Prior To Disease Onset, Seiji Ohno, Hongfang Yu, Douglas Dickinson, Tin-Chun Chu, Kalu Ogbureke, Scott Derossi, Tetsuya Yamamoto, Stephen Hsu
Tin-Chun Chu, Ph.D.
No abstract provided.
Protamine-Like Proteins In 12 Sequenced Species Of Drosophila, Zain Alvi, Tin-Chun Chu, Valerie Schawaroch, Angela Klaus
Protamine-Like Proteins In 12 Sequenced Species Of Drosophila, Zain Alvi, Tin-Chun Chu, Valerie Schawaroch, Angela Klaus
Tin-Chun Chu, Ph.D.
No abstract provided.
Identification And Bioinformatic Analyses Of Vanillate Operon In Cyanobacterium Synechococcus Sp. Iu 625, Robert Newby, Tin-Chun Chu
Identification And Bioinformatic Analyses Of Vanillate Operon In Cyanobacterium Synechococcus Sp. Iu 625, Robert Newby, Tin-Chun Chu
Tin-Chun Chu, Ph.D.
No abstract provided.
Bioinformatic Analysis Of Cyanobacterial Mercuric Resistance Genes And Identification Of Synechococcus Sp. Iu 625 Putative Mercuric Resistance Genes, Lee Lee, Chiedozie Okafor, Matthew Rienzo, Tin-Chun Chu
Bioinformatic Analysis Of Cyanobacterial Mercuric Resistance Genes And Identification Of Synechococcus Sp. Iu 625 Putative Mercuric Resistance Genes, Lee Lee, Chiedozie Okafor, Matthew Rienzo, Tin-Chun Chu
Tin-Chun Chu, Ph.D.
No abstract provided.
Molecular Probes For The Detection Of Cyanophage As-1 And Its Cyanobacterial Hosts., Tin-Chun Chu, Jonathan Jimenez, Lauren Strawn, Michelle Reed, Lauren Pohren, Lee Lee
Molecular Probes For The Detection Of Cyanophage As-1 And Its Cyanobacterial Hosts., Tin-Chun Chu, Jonathan Jimenez, Lauren Strawn, Michelle Reed, Lauren Pohren, Lee Lee
Tin-Chun Chu, Ph.D.
No abstract provided.
Identification Of Synechococcus Sp. Iu 625 Phycocyanin Gene And Bioinformatic Analyses Of Cyanobacterial Phycocyanin., Tin-Chun Chu, Aline Oliveira, Arti Rana, Lee Lee
Identification Of Synechococcus Sp. Iu 625 Phycocyanin Gene And Bioinformatic Analyses Of Cyanobacterial Phycocyanin., Tin-Chun Chu, Aline Oliveira, Arti Rana, Lee Lee
Tin-Chun Chu, Ph.D.
No abstract provided.
The Evolution Of Flight In Insects: Insights From Mayflies And Dna, T. Heath Ogden
The Evolution Of Flight In Insects: Insights From Mayflies And Dna, T. Heath Ogden
T. Heath Ogden
No abstract provided.
Biomedical Research And The Law:--Embryonic Stem Cells, Clones And Genes: Science, Law, Politics, And Values, Michael J. Malinowski
Biomedical Research And The Law:--Embryonic Stem Cells, Clones And Genes: Science, Law, Politics, And Values, Michael J. Malinowski
Michael J. Malinowski
This article directly addresses the stem cell controversy, but also the broader history and norms regarding the roles of federal and state government in U.S. science research funding.
Identification Of Synechococcus Sp. Iu 625 Metallothionein Gene And Its Evolutionary Relationship To The Metallothionein Gene Of Other Cyanobacteria, Tin-Chun Chu, Lee Lee, John Gaynor, Quinn Vega, Bonnie Lustigman, Shankar Srinivasan
Identification Of Synechococcus Sp. Iu 625 Metallothionein Gene And Its Evolutionary Relationship To The Metallothionein Gene Of Other Cyanobacteria, Tin-Chun Chu, Lee Lee, John Gaynor, Quinn Vega, Bonnie Lustigman, Shankar Srinivasan
Tin-Chun Chu, Ph.D.
No abstract provided.
Multiple Sequence Alignment Accuracy And Phylogenetic Inference, T. Heath Ogden, Michael S. Rosenberg
Multiple Sequence Alignment Accuracy And Phylogenetic Inference, T. Heath Ogden, Michael S. Rosenberg
T. Heath Ogden
Phylogenies are often thought to be more dependent upon the specifics of the sequence alignment rather than on the method of reconstruction. Simulation of sequences containing insertion and deletion events was performed in order to determine the role that alignment accuracy plays during phylogenetic inference. Data sets were simulated for pectinate, balanced, and random tree shapes under different conditions (ultrametric equal branch length, ultrametric random branch length, nonultrametric random branch length). Comparisons between hypothesized alignments and true alignments enabled determination of two measures of alignment accuracy, that of the total data set and that of individual branches. In general, our …