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Full-Text Articles in Genomics
Phylogenetic History Of The Amy Gene Cluster In Catarrhines, Christian M. Gagnon
Phylogenetic History Of The Amy Gene Cluster In Catarrhines, Christian M. Gagnon
Theses and Dissertations
This study phylogenetically analyzed 30 AMY-related genes from 11 primates. The results show the gradual expansion of the AMY gene family which could have allowed primates to adapt to various ecological landscapes and maximize energy intake from starch-rich foods in periods of food scarcity.
Genome-Wide Systems Genetics Of Alcohol Consumption And Dependence, Kristin Mignogna
Genome-Wide Systems Genetics Of Alcohol Consumption And Dependence, Kristin Mignogna
Theses and Dissertations
Widely effective treatment for alcohol use disorder is not yet available, because the exact biological mechanisms that underlie this disorder are not completely understood. One way to gain a better understanding of these mechanisms is to examine the genetic frameworks that contribute to the risk for developing this disorder. This dissertation examines genetic association data in combination with gene expression networks in the brain to identify functional groups of genes associated with alcohol consumption and dependence.
The first study took advantage of the behavioral complexity of human samples, and experimental capabilities provided by mouse models, by co-analyzing gene expression networks …