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Full-Text Articles in Genomics
Evolution And Epidemiology Of Channel Catfish Virus (Ccv), Arun Venugopalan
Evolution And Epidemiology Of Channel Catfish Virus (Ccv), Arun Venugopalan
Theses and Dissertations
Channel catfish virus disease (CCVD) is the principal viral disease in the United States catfish industry. The CCVD is caused by channel catfish virus (CCV), with mortality reaching up to 100% in fingerlings. CCV is assigned taxonomically to the family Alloherpesviridae, genus Ictalurivirus, species Ictalurid herpesvirus 1 (IcHV-1). To date, virulence, immunogenicity, and genome plasticity of the CCV field isolates have not been investigated. Three genotypes of CCV (IcHV-1A, IcHV-1B, and BCAHV) were identified using restriction fragment length polymorphism (RFLP) analysis. Virulence assessment of three representative isolates of RFLP groups suggests that IcHV-1B (pooled survival [mean ± SE]: 58.3% ± …
Comparative Genome Analyses Reveal Distinct Structure In The Saltwater Crocodile Mhc., Weerachai Jaratlerdsiri, Janine Deakin, Ricardo M. Godinez, Xueyan Shan, Daniel G. Peterson, Sylvain Marthey, Eric Lyons, Fiona M. Mccarthy, Sally R. Isberg, Damien P. Higgins, Amanda Y. Chong, John St. John, Travis C. Glenn, David A. Ray, Jaime Gongora
Comparative Genome Analyses Reveal Distinct Structure In The Saltwater Crocodile Mhc., Weerachai Jaratlerdsiri, Janine Deakin, Ricardo M. Godinez, Xueyan Shan, Daniel G. Peterson, Sylvain Marthey, Eric Lyons, Fiona M. Mccarthy, Sally R. Isberg, Damien P. Higgins, Amanda Y. Chong, John St. John, Travis C. Glenn, David A. Ray, Jaime Gongora
College of Agriculture & Life Sciences Publications and Scholarship
The major histocompatibility complex (MHC) is a dynamic genome region with an essential role in the adaptive immunity of vertebrates, especially antigen presentation. The MHC is generally divided into subregions (classes I, II and III) containing genes of similar function across species, but with different gene number and organisation. Crocodylia (crocodilians) are widely distributed and represent an evolutionary distinct group among higher vertebrates, but the genomic organisation of MHC within this lineage has been largely unexplored. Here, we studied the MHC region of the saltwater crocodile (Crocodylus porosus) and compared it with that of other taxa. We characterised genomic clusters …