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Targeted Germ Cell Knockdown Of Xlr3 In Mus Musculus, Caity Miller
Targeted Germ Cell Knockdown Of Xlr3 In Mus Musculus, Caity Miller
Honors Scholar Theses
The X chromosome is rather distinct from autosomes due to the unique regulatory and functional characteristics it exhibits. Xlr3 is just one gene in a superfamily of highly related, and homologous genes found on the X chromosome in mice. Xlr3 is part of a complex, imprinted locus, of which the function is not well understood, although its protein product can be found in testis and oocyte. However, it is theorized that the region may be implicated in the progression of meiosis, due to localization of XLR3. This study sought to characterize the function of Xlr3 through the use of a …