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Full-Text Articles in Developmental Biology
Effects Of Meiotic Drive On Developing Eye-Stalks In Stalk-Eyed Flies, Christopher Lepore, Olivia Smith, Heather Wood, Josephine Reinhardt Phd
Effects Of Meiotic Drive On Developing Eye-Stalks In Stalk-Eyed Flies, Christopher Lepore, Olivia Smith, Heather Wood, Josephine Reinhardt Phd
McNair Scholars Program
Teleopsis dalmanni, commonly known as Stalk-Eyed flies, are known for their sexually dimorphic eye-stalks which females use to pick mates. Within the Gombak-12 population, some individuals contain meiotic drive which is known to influence eye-stalk length and sex ratios. Our goal was to identify genes in developing eye tissue that play a role in causing meiotic drive. To identify these candidate genes, we determined the sex and meiotic drive status of individuals by dissecting 3rd instar larvae for their carcasses. After finding that Qiagen Puregene and Qiagen DNEasy columns DNA extraction techniques worked best—determined by using gel electrophoresis—we prepared …
Effects Of Bisphenol-S And Estrogen On P53 Expression In Ovarian Tissue Of Zebrafish (Danio Rerio), Jess Fairbanks
Effects Of Bisphenol-S And Estrogen On P53 Expression In Ovarian Tissue Of Zebrafish (Danio Rerio), Jess Fairbanks
Summer Research
Bisphenol A (BPA) is one the most widely used plasticizing compounds. As an endocrine disruptor, BPA could affect ovarian function and embryonic development. Bisphenol S (BPS) has been used in many plastics and resins in lieu of BPA. However, the effects of BPS are not widely known. Apoptosis is a type of genetically programmed cell death that is important in ovarian homeostasis. One of the genes that regulates apoptosis, p53, has been shown to respond to estrogen in maintaining ovarian homeostasis. We have investigated how exposure to estrogen and to BPS affects p53 expression in ovarian tissue in vitro …