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Full-Text Articles in Cell Biology
Staying Hydrated: A Comparative Analysis Of Humectants In Human Skin, Ayden Olsen, Rachel Prince, Craig Reeves, Cassie Peterson, Jason Adams
Staying Hydrated: A Comparative Analysis Of Humectants In Human Skin, Ayden Olsen, Rachel Prince, Craig Reeves, Cassie Peterson, Jason Adams
Library/Life Sciences Undergraduate Poster Competition 2022
Humectants are an important class of compounds that attract and retain water within a cell. When mixed with water to create wetting solutions, humectants can prevent desiccation of cadaveric specimens. Recognizing a relative scarcity of comparative studies analyzing the effects of various wetting solutions on post preservation cadaveric maintenance, we utilized wet-dry analysis in order to compare the effects of four common humectants on water retention in human skin tissue. We created a concentration gradient for each humectant to identify the optimal concentrations of each compound for water retention, after which we compared water retention in tissue at the optimal …
New Treatment For Multiple Sclerosis Could Halt Disease Progression Without Weakening Immune System, Carter Helquist, Dario Mizrachi
New Treatment For Multiple Sclerosis Could Halt Disease Progression Without Weakening Immune System, Carter Helquist, Dario Mizrachi
Library/Life Sciences Undergraduate Poster Competition 2022
- Multiple Sclerosis (MS) is a debilitating neurological and autoimmune disease in which immune cells cause demyelination of axons in nervous tissue.
- Current treatments for the disease are principally aimed at weakening the immune system to therefore weaken the autoimmune attack on the brain. This leaves patients prone to other sicknesses.
- We seek a treatment that prevents the immune cells from entering the central nervous system (CNS) thereby protecting its cells.
- We can prevent immune cells from entering the CNS by strengthening the blood brain barrier through targeting claudin 5 proteins in the tight junctions.
- This new treatment could mean increased …
Protein 14-3-3 (Ywha) Isoforms And Their Roles In Regulating Mouse Oocyte Maturation, Santanu De
Protein 14-3-3 (Ywha) Isoforms And Their Roles In Regulating Mouse Oocyte Maturation, Santanu De
Biology Faculty Books and Book Chapters
The 14-3-3 (YWHA) is a highly conserved, ubiquitously expressed protein family regulating important cellular processes including cell cycle. This work, for the first time, explored the differential expression and roles of 14-3-3 isoforms during mouse oocyte maturation.
All seven mammalian 14-3-3 isoforms were identified in mouse eggs and ovarian follicular cells including oocytes, by Western blotting. Immunocytochemical and immunohistochemical staining confirmed the presence of all 14-3-3 isoforms in oocytes, eggs and ovarian follicles with characteristic similarities and differences in their distributions.
Mammalian oocytes are arrested at meiosis prophase I by an inhibitory phosphorylation on Cyclin-Dependent Kinase I (CDK1), released by …