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Fertilization And Mouse Embryo Development In The Presence Of Midazolam, Maria Leavitt
Fertilization And Mouse Embryo Development In The Presence Of Midazolam, Maria Leavitt
Biological Sciences Theses & Dissertations
The development of mouse embryos in vitro has provided a unique opportunity for the study of cellular differentiation and the influence of various agents on differentiation. Midazolam is administered for conscious sedation in the recovery of human ova. In the Norfolk IVF Program, midazolam is found in varying concentrations in follicular fluid. Mouse embryo formation and development has been used to test midazolam's effect on fertilization and early development as a model of human in vitro fertilization and development. Midazolam' s effects were studied using varying doses of midazolam on (1) in vivo fertilization and subsequent cell division, and (2) …