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Tattletales And T-Bow Update 20141018, George Mcnamara
Tattletales And T-Bow Update 20141018, George Mcnamara
George McNamara
Tattletales and T-Bow Update 20141018
http://works.bepress.com/gmcnamara/63
Tattletales is my concept to multiplex fluorescent protein biosensors ("Tattletales", which is also the overall concept name) and multicolor FP reporters ("T-Bow" for Rainbow T-cells and tumor cells) to study the physiology of live cells.
These are based on:
1. LacI-GFP :: LacO operator synthetic tandem repeat array (Robinett et al 1996 JCB, Fig 4A, http://jcb.rupress.org/content/135/6/1685.full.pdf )
2. the plethora of fluorescent protein biosensors - see page 1 of this "63" download site.
3. the many colors, and combinations of colors (CY11.5, CyPet-YPet 90% FRET, simple color combination fusions, Steven Vogel's "V6" and "V8" …