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Cell Biology Commons

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Cedarville University

2012

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Full-Text Articles in Cell Biology

Acth: The Uninhibitable (Or Is It)?, Anthony Baglio, Jonathan Forsberg, Daniel Mcfarlane, Justin Nichols, Heather G. Kuruvilla Jan 2012

Acth: The Uninhibitable (Or Is It)?, Anthony Baglio, Jonathan Forsberg, Daniel Mcfarlane, Justin Nichols, Heather G. Kuruvilla

Science and Mathematics Faculty Presentations

Adrenal corticotropic hormone, or ACTH, is a peptide hormone secreted by the anterior pituitary gland. The full-length peptide is 39 amino acids long. ACTH signals through a G-protein linked receptor in humans, using the adenylyl cyclase pathway. Potassium and chloride channels have also been implicated in human ACTH signaling.

Tetrahymena thermophila are free-living, ciliated ptotozoans. These organisms exhibit avoidance behavior toward many polycationic peptides, which serve as chemorepellents. The reason for this is unknown; however, it is hypothesized that natural predators of T. thermophila secrete polycationic peptides, and that polycation avoidance allows T. thermophila to escape predation. We obtained a …