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Full-Text Articles in Molecular Biology
Biochemistry Of 1, 2-Dehydro-N-Acetyldopamine Derivatives, Adal T. Abebe
Biochemistry Of 1, 2-Dehydro-N-Acetyldopamine Derivatives, Adal T. Abebe
Graduate Doctoral Dissertations
Dehydrodopa/dopamine derivatives form an important group of biomolecules participating in sclerotization of all arthropod cuticles, gluing and cementing mussels and related organisms to solid surfaces, and defense reactions of countless marine and invertebrate organisms. Yet very little information is available on the biochemistry of these highly reactive and unstable molecules. To understand their physiological role, I conducted a thorough biochemical study on three representative compounds that cover the entire plethora of dehydrodopa/dopamine derivatives. Employing diode array UV-visible spectroscopy, HPLC, liquid chromatography-mass spectrometry, and electrospray ionization tandem mass spectrometry, I investigated the oxidation chemistry of 1,2-dehydro-N-acetyldopamine (dehydro NADA), 1,2-dehydro-N-acetyldopa and 1,2-dehydro-N-acetyldopa …
Elucidating The Role Of Dopamine In The Avoidance Response Of Caenorhabditis Elegans Utilizing Microfluidics, Patricia Frances Turturro
Elucidating The Role Of Dopamine In The Avoidance Response Of Caenorhabditis Elegans Utilizing Microfluidics, Patricia Frances Turturro
Theses Digitization Project
This study looks at dopamine modulation of ASH neurons, which are part of the avoidance circuit of C. elegans, and their response to water soluble stimuli. Because nematodes such as Caenorhabditis elegans utilize dopamine at the molecular and cellular level in much the same way as mammals, they offer researchers a unique opportunity to study the mechanisms of dopamine signaling.
Cell Type Difference In Influenza A Viral Mrna Nuclear Export, Sean William Larsen
Cell Type Difference In Influenza A Viral Mrna Nuclear Export, Sean William Larsen
Theses Digitization Project
The focus of this thesis research was to clarify the role of host Nxf1 in influenza viral mRNA nuclear export. This study aims to define the nuclear mRNA export pathways of influenza viral mRNA. If viral mRNAs are discovered to utilize neither known mRNA nuclear export pathway this would indicate the mRNA exports via undefined mRNA nuclear export pathway. This might be an atypical pathway not utilized by many host mRNAs and thus might reveal novel antiviral target. 293T (Human embryonic kidney cells) and A549 (Human lung epithelial) cells were purchased from ATCC American Tissue Culture Collection.