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Full-Text Articles in Molecular Biology
Bilirubin-Albumin Binding At Varying Conditions Of Hematocrit, Sodium Benzoate Concentration, And Bilirubin/Albumin Molar Ratios, Patrick Ahrens
Life and Environmental Sciences Undergraduate Theses
Hyperbilirubinemia, which causes jaundice, is quite common in newborns. Typically bilirubin is bound to its carrier protein albumin and very little unbound bilirubin is present in the blood. However, in cases of hyperbilirubinemia there is a marked increase in unbound bilirubin, which can be toxic. The two methods traditionally used to treat hyperbilirubinemia are exchange transfusion and phototherapy. Each of these methods have drawbacks. The Department of Chemical, Bio, and Materials Engineering at Arizona State University is currently developing an extra-corporeal hemoperfusion column that will remove the unbound bilirubin fraction from the blood of jaundiced patients. This column utilizes coated ...