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Full-Text Articles in Molecular Biology
Analysis Of The Induction Of Autophagy During Er Stress And The Vesicle Fusion Machinery At The Trans-Golgi Network In Arabidopsis Thaliana, Xiaochen Yang
Graduate Theses and Dissertations
The vacuole in plant cells occupies more than 80% of the cellular volume and is involved in development, detoxification, and degradation of proteins. In this dissertation, I focused on the two vesicle trafficking pathways, autophagy and vacuolar trafficking, which deliver cellular components to the vacuole.
Autophagy is an evolutionarily conserved mechanism in eukaryotic cells for degradation and recycling of cytoplasmic materials and damaged cell components during development or upon encountering stress conditions. Previous studies showed that autophagy is activated by endoplasmic reticulum (ER) stress and delivers ER fragments to the vacuole. ER stress is defined as accumulation of unfolded or ...