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Molecular Biology Commons

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Theses/Dissertations

Wright State University

P53

2020

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Full-Text Articles in Molecular Biology

Alternative Splicing Of Mdm4 In Human Melanomas, Abdullah Salem S. Alatawi Jan 2020

Alternative Splicing Of Mdm4 In Human Melanomas, Abdullah Salem S. Alatawi

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Melanoma is a potentially lethal type of skin cancer and regarded to be the third most common type of skin cancer. Although melanoma is not as common as basal cell carcinoma (BCC) and squamous cell carcinoma (SCC), it is more likely to metastasize than BCC and SCC. Interestingly, the incidence of melanoma continues to go up (expected 2% in 2020), but the deaths continue to decrease (-5.3% in 2020) due to improvements in detection and treatment. The treatment of melanoma depends on several aspects but most importantly the tumor's stage and the location. In the early stages, melanoma can be …