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Investigation Of The Interactions Between The Dream Complex And Hpv16, Kevin Ko
Investigation Of The Interactions Between The Dream Complex And Hpv16, Kevin Ko
Theses and Dissertations
According to the American Cancer Society, it has been estimated that in 2019 alone, there will be approximately 53,000 new cases of oropharyngeal cancers. Oropharyngeal cancers are the largest subset of head and neck squamous cell carcinomas (HNSCCs), which are the sixth most common cancer across worldwide populations. They, along with other HNSCCs, fall under a category of cancers known as Human papillomavirus (HPV)-associated cancers, and it has been found that upwards of 70% of these cancers can be attributed to high-risk HPV infections.
Specifically, the high-risk HPV gene, E7, plays a key role in relieving cell cycle repression by …