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Full-Text Articles in Molecular Biology
Swarna Ramaswamy_Thesis, Swarna S. Ramaswamy
Swarna Ramaswamy_Thesis, Swarna S. Ramaswamy
Dissertations & Theses (Open Access)
STRUCTURAL INVESTIGATIONS OF LIGAND GATED ION CHANNELS
Swarna Ramaswamy, B.S
Advisor: Vasanthi Jayaraman, Ph.D.
Ion channels form an integral part of membrane proteins. In the nervous system including the central and the peripheral nervous system, ligand gated ion channels form a very important part of intercellular communications. They receive chemical signals and convert them to electrical signal, mainly by allowing ion passage across the cell membrane. Ion passage also translates into downstream signaling events. Faithful translation of these signals and transmittance is crucial for several physiological functions, implying that irregular ion channel function could lead to serious consequences.
This thesis …