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Full-Text Articles in Molecular Biology
Host Signaling Response To Adhesion Of Bifidobacterium Infantis, Reed N. Gann
Host Signaling Response To Adhesion Of Bifidobacterium Infantis, Reed N. Gann
All Graduate Theses and Dissertations, Spring 1920 to Summer 2023
Investigations of the molecular binding partners of the probiotic bacterium Bifidobacterium longum subspecies infantis (B. infantis) and the pathogen Salmonella enterica subspecies enterica serovar Typhimurium LT2 (Salmonella ser. Typhimurium) found that these two very different bacteria bind gangliosides. However, these organisms lead to completely different host health outcomes when present in the gut. B. infantis is the founding microbial population in the intestinal tract of breast-fed infants. S. typhimurium is the most important food-borne pathogen that results in humans. This study used an in vitro gut epithelial cell model to examine the host cellular response to adhesion …