Open Access. Powered by Scholars. Published by Universities.®
- Keyword
-
- A. thaliana (1)
- Aequorin (1)
- Aequorin-calcium assay (1)
- Arabidopsis (1)
- Arabidopsis thaliana (1)
-
- Bacteria (1)
- Biology (1)
- Biotechnology (1)
- Burkholderia cepacia complex (1)
- Chemistry (1)
- Cloning; Characterization; Cell; Wall; Enzyme; CD1034; Pathogen; Clostridium difficile; resistance; bacteria; antimicrobial; antibacterial; (1)
- Cum laude (1)
- Cystic fibrosis (1)
- Effectors (1)
- Elicitors (1)
- Host-pathogen interactions (1)
- Immune system (1)
- Innate immune system (1)
- Innate immunity (1)
- MAMP response (1)
- MAMPs (1)
- MPK4 (1)
- Mitogen-activated protein kinase 4 (1)
- P. syringae (1)
- PAMP response (1)
- PAMPs (1)
- PRRs (1)
- Pathogen (1)
- Plants (1)
- Pseudomonas (1)
Articles 1 - 3 of 3
Full-Text Articles in Molecular Biology
Host Pathogen Interactions: Is Arabidopsis Thaliana Remembered By Its Nemesis Pseudomonas Syringae?, Daniel Z. Kreiser
Host Pathogen Interactions: Is Arabidopsis Thaliana Remembered By Its Nemesis Pseudomonas Syringae?, Daniel Z. Kreiser
Lawrence University Honors Projects
Plants contain innate immune systems that deter pathogen infection. Pattern recognition receptors bind microbe-associated molecular patterns (MAMPs), triggering immunity. MAMPs are proteins exclusive to pathogens that are typically indispensable for their survival. For this reason, MAMPs cannot be mutated or removed without causing pathogen death. However, this does not necessitate constitutive expression of MAMPs. In this study, the MAMP response of Arabidopsis thaliana was utilized to determine differential detection of MAMPs expressed by Pseudomonas syringe pv. tomato DC3000 when pretreated with A. thaliana. Results demonstrated that more MAMPs are detected when P. syringae had previously encountered A. thaliana, …
Cloning And Characterization Of The Cell Wall Acting Enzyme Cd1034 From The Pathogen Clostridium Difficile, Zachary Suter
Cloning And Characterization Of The Cell Wall Acting Enzyme Cd1034 From The Pathogen Clostridium Difficile, Zachary Suter
Honors Projects in Science and Technology
The manifestation of multidrug resistance in bacteria over the past several decades has resulted in one of the foremost challenges in the management of infectious diseases. The question arises, “How do we address this growing problem?” One solution to stem the growing rise in antimicrobial resistance is to investigate new targets, while another approach is to re-examine classical antibacterial targets with a fresh perspective. The aim of this paper is to begin the process of antibacterial development for the pathogen Clostridium difficile by characterizing the cell wall acting glucosaminidase CD1034. It is inunderstanding how CD1034 functions biochemically that it can …
Bacterial Host Interactions In Cystic Fibrosis, Máire Callaghan, Siobhan Mcclean
Bacterial Host Interactions In Cystic Fibrosis, Máire Callaghan, Siobhan Mcclean
Articles
Chronic infection is a hallmark of cystic fibrosis (CF) and the main contributor to morbidity. Microbial infection in CF is complex, due to the number of different species that colonise the CF lung. Their colonisation is facilitated by a host response that is impaired or compromised by highly viscous mucous, zones of hypoxia and the lack of the cystic fibrosis transmembrane regulator (CFTR). Successful dominant CF pathogens combine an effective arsenal to establish infection and counter-attack the host response, together with an ability to adapt readily to an unfavourable environment. Hypermutability is common among CF pathogens facilitating adaptation and as …