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Full-Text Articles in Molecular Biology
Peroxiredoxin 6 And Inflammation In Alzheimer's Disease, Jared Ferrell-Penniman
Peroxiredoxin 6 And Inflammation In Alzheimer's Disease, Jared Ferrell-Penniman
Biological Sciences Theses and Dissertations
Alzheimer’s disease (AD) is known for its debilitating symptoms and poor prognosis. However, despite intense research into neurodegenerative diseases, there are few therapies targeted at the underlying mechanisms of the disease. Oxidative stress (OS) and inflammation are cellular phenomena thought to be key to the progression of the disease. Critically, peroxiredoxin 6 (Prx6), an antioxidant protein with multiple functions, has been identified from mammalian studies as a potential regulator of both OS and inflammation that may have a specific effect on AD. This project seeks to elucidate the role of Prx6 in AD as well as the underlying mechanisms. Drosophila …
How A Cell Knows Where To Divide: Oscillation Of Mind In Vivo, Colby Ferreira
How A Cell Knows Where To Divide: Oscillation Of Mind In Vivo, Colby Ferreira
Senior Honors Projects
Over two-million people in the United States are infected by antibiotic resistant bacteria each year. Of this number 23,000 die from these infections and other complications. Due to this, novel antibiotic targets are constantly being investigated. One process in prokaryotes that holds promise is cellular division. Bacterial cells grow and reproduce using a series of proteins known as the cell division machinery. This machinery enables the division of the parental cell into two identical daughter cells. The cell division machinery is similar between bacterial taxa, making it an ideal target for new classes of antibiotics. Therefore, understanding the molecular mechanisms …