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- 20-hydroxyecdysone; Calmodulin; Drosophila melanogaster; Fruit-flies; Nuclear receptors (Biochemistry); Salivary glands; Steroid hormones (1)
- Bacterial transformation; Genetic transcription; IcsP; Microbial genetics; Shigella flexneri; Transcription factors (1)
- Biodiversity; Biogeography; Biogeography — Climatic factors; Birds – Evolution; Birds – Geographical distribution; Evolution (Biology); Molecular genetics; North America; Paleobiogeography; Population genetics; South America (1)
- Chromatin immunoprecipitation (1)
- Golden-mantled ground squirrel (1)
Articles 1 - 4 of 4
Full-Text Articles in Molecular Biology
Global And Specific Controls Of Protein Synthesis In Hibernators, Peipei Pan
Global And Specific Controls Of Protein Synthesis In Hibernators, Peipei Pan
UNLV Theses, Dissertations, Professional Papers, and Capstones
Mammalian hibernation is a highly dynamic physiological process that is composed of a series of torpor bouts, wherein hibernators oscillate between periods of torpor and interbout arousal. Although normally vital to homeostasis, many energetically consumptive processes such as translation or protein synthesis are virtually ceased during hibernation. Earlier studies indicated that protein synthesis had fallen to almost negligible levels. Cap-dependent initiation of translation is well regulated by eukaryotic translation initiation factor 4E (eIF4E) and its binding partner eIF4E-binding protein 1 (4E-BP1) when hibernators cycle in and out the torpor state. Herein, I investigated well-characterized regulatory mechanisms of global and specific …
Molecular Evolution And Historical Biogeography Of New World Birds, Brian T. Smith
Molecular Evolution And Historical Biogeography Of New World Birds, Brian T. Smith
UNLV Theses, Dissertations, Professional Papers, and Capstones
Deciphering the patterns of how biodiversity has evolved across time and space has remained a fundamental objective for biologists for the last 200 years. Researchers are faced with the challenge of interpreting the complexity of evolutionary patterns that have been generated over the deep history of the Earth. The advancement of DNA sequencing technology has yielded a new and powerful genetic toolkit that has allowed biologists to address novel evolutionary questions. For my dissertation research, I used molecular genetics and a statistical framework to study the evolution and historical biogeography of birds distributed in North and South America. My dissertation …
Transcriptional Regulation Of Shigella Virulence Plasmid-Encoded Genes By Virb And Crp, Christopher Thomas Hensley
Transcriptional Regulation Of Shigella Virulence Plasmid-Encoded Genes By Virb And Crp, Christopher Thomas Hensley
UNLV Theses, Dissertations, Professional Papers, and Capstones
Shigella flexneri is a species of Gram-negative intracellular pathogens that causes bacillary dysentery in humans. Shigella relies on the precise transcriptional regulation of virulence genes, encoded by a large virulence plasmid, for invasion and infection of human colonic epithelial cells. The transcription of most identified virulence genes are regulated through a cascade controlled by the primary regulator of virulence genes, VirF, and the global transcriptional regulator, VirB. Currently, few studies have addressed how individual Shigella virulence genes are precisely regulated for optimal expression during specific stages of pathogenesis and within the constraints of the regulatory cascade. This work addresses how …
The Larval Salivary Gland Of Drosophila Melangogaster: A Model System For Temporal And Spatial Steroid Hormone Regulation, Benjamin Constantino
The Larval Salivary Gland Of Drosophila Melangogaster: A Model System For Temporal And Spatial Steroid Hormone Regulation, Benjamin Constantino
UNLV Theses, Dissertations, Professional Papers, and Capstones
Drosophila melanogaster provides an ideal model organism to test genetic and molecular biological mechanisms within the context of a living animal. For over one hundred years Drosophila continues to produce a boundless extent of informative and important scientific data providing crucial insight into development, disease progression and genetic interactions. A century as a model organism allowed for the development of an abundance of unique genetic and molecular tools allowing researchers to tease apart cellular mechanisms with very little limitation. From the whole adult body to tissue function to molecular networks, if a biological question arises it most likely can be …