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Full-Text Articles in Molecular Biology

Understanding The Role Of Rhamm In Tumor Load– Mediated Tumor Invasiveness Of Triple Negative Breast Cancer, Ashwin Sritharan, Britney Messam Aug 2021

Understanding The Role Of Rhamm In Tumor Load– Mediated Tumor Invasiveness Of Triple Negative Breast Cancer, Ashwin Sritharan, Britney Messam

Undergraduate Student Research Internships Conference

1.Compare the levels of proliferation between RHAMM+/+ and RHAMM -/- MDA-MB-231 spheroids as determined by ki67 and Caspase 3 signaling 2.Compare levels of RHAMM, CD44, Has2, and p-ERK activation between RHAMM+/+ and RHAMM -/- MDA-MB-231 spheroids


Detecting A-Series Ganglioside Expression Profile Changes During Microglial Activation, Mona M. Alshaikh Apr 2018

Detecting A-Series Ganglioside Expression Profile Changes During Microglial Activation, Mona M. Alshaikh

Electronic Thesis and Dissertation Repository

With aging, our brains become more susceptible to disease and injury. Different regions of the brain have differing levels of vulnerability to stress and injury, and this brain region-dependent variability to vulnerability could be partly explained by the existence of glycosphingolipids within the cell’s plasma membrane called gangliosides. Gangliosides are expressed predominantly within the brain and play various roles within the central nervous system including neural repair, cell survival, and neurodegeneration. Our laboratory has demonstrated that gangliosides can shift their composition from GM1 back to GM2 and GM3 following stroke in mice and rats indicating a role for simple gangliosides …