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Articles 181 - 182 of 182

Full-Text Articles in Biochemistry, Biophysics, and Structural Biology

Signal Processing In Bacterial Chemotaxis, Jimmie Marquette Smith Sep 1987

Signal Processing In Bacterial Chemotaxis, Jimmie Marquette Smith

Loma Linda University Electronic Theses, Dissertations & Projects

This study localized 1) the site of ATP utilization in the signal transduction pathway of bacterial chemotaxis and 2) the point of convergence of the methylation-independent systems of chemotaxis with the methylation-dependent system. The site of ATP utilization was localized at the CheY protein/switch point. In an Eaeheriehia call strain (BT3077) containing the cheY, motor and switch genes, ATP depletion, accomplished by treating the cells with arsenate, suppressed the CheY protein-induced tumbling. ATP was not required by the switch for directing the clockwise and counterclockwise rotations of the flagellar motor. ATP did not appear to be required for normal steady-state …


Mathematical Model Of Placental Oxygen And Carbon Dioxide Exchange, Ester P. Hill Dec 1971

Mathematical Model Of Placental Oxygen And Carbon Dioxide Exchange, Ester P. Hill

Loma Linda University Electronic Theses, Dissertations & Projects

This model of placental CO2 and O2 exchange calculates the time course of changes in PCO2, [HCO3-], and [H+] in each of four "compartments" of placental exchange vessels: maternal erythrocytes, maternal plasma, fetal plasma and fetal erythrocytes. The changes in hemoglobin-bound CO2 (carbamate) and oxyhemoglobin contents within the erythrocytes are also calculated, permitting consideration of the Haldane and Bohr effects. Equations were written to represent one-dimensional steady state CO2 and O2 diffusion between concurrent maternal and fetal capillaries and the subsequent hydration, carbamino and oxyhemoglobin reactions. The equations …