Biochemistry, Biophysics, and Structural Biology Commons^™

Do Bha And Bht Induce Morphological Changes And Dna Double-Strand Breaks In Schizosaccharomyces Pombe?, Amy V. Tran

Scripps Senior Theses

Butylated Hydroxyanisole, BHA, and Butylated Hydroxytoluene, BHT, are commonly used as preservatives for our food as well as additives in many products such as cosmetics, petroleum, and medicine. Although their use has been approved by the Food and Drug Administration (FDA), there have been controversies and debates on whether these phenol derivatives or antioxidants are safe to use. Their accumulative toxicology and side effects need to be thoroughly investigated as we continue to consume them on a daily basis. Data obtained by genomic analysis in Tang lab suggested the involvement of DNA damage checkpoint/repair pathways in the response network to …