Open Access. Powered by Scholars. Published by Universities.®
Biochemistry, Biophysics, and Structural Biology Commons™
Open Access. Powered by Scholars. Published by Universities.®
- Institution
-
- Selected Works (17)
- City University of New York (CUNY) (5)
- Georgia Southern University (5)
- University of South Florida (5)
- University of Massachusetts Amherst (4)
-
- Purdue University (3)
- The Texas Medical Center Library (3)
- University at Albany, State University of New York (3)
- Washington University in St. Louis (3)
- Wayne State University (3)
- Florida International University (2)
- Himmelfarb Health Sciences Library, The George Washington University (2)
- Old Dominion University (2)
- University of Missouri, St. Louis (2)
- University of Northern Iowa (2)
- University of South Carolina (2)
- University of Tennessee, Knoxville (2)
- Virginia Commonwealth University (2)
- Western Michigan University (2)
- Andrews University (1)
- Boise State University (1)
- Bowling Green State University (1)
- Butler University (1)
- California Polytechnic State University, San Luis Obispo (1)
- DePaul University (1)
- DePauw University (1)
- East Tennessee State University (1)
- Fordham University (1)
- Illinois State University (1)
- Missouri University of Science and Technology (1)
- Keyword
-
- Apoptosis (4)
- RNA (4)
- Biology (3)
- Drosophila (3)
- Aging (2)
-
- Aptamer (2)
- Biomass (2)
- C. elegans (2)
- Chaperone (2)
- Collagen (2)
- Heat shock proteins (2)
- Molecular chaperones (2)
- Stress (2)
- Transcription (2)
- Transport (2)
- 1.6 BIOLOGICAL SCIENCES (1)
- 20q (1)
- <p>G proteins -- Receptors -- Research<br />Cell receptors<br />Cellular signal transduction</p> (1)
- ABCG2 (1)
- ATP (1)
- AURKA (1)
- Acer rubrum (1)
- Activation induced cytidine deaminase (1)
- Algae (1)
- Allele (1)
- Allene oxide cyclase gene (1)
- Allied health (1)
- Allosteric regulation (1)
- American (1)
- Amino acid substitution (1)
- Publication
-
- Joan Slonczewski (12)
- Department of Biology Faculty Publications (5)
- Masters Theses (5)
- USF Tampa Graduate Theses and Dissertations (5)
- Biology Faculty Publications & Presentations (3)
-
- Dissertations & Theses (Open Access) (3)
- Legacy Theses & Dissertations (2009 - 2024) (3)
- Theses and Dissertations (3)
- Wayne State University Dissertations (3)
- Dissertations, Theses, and Capstone Projects (2)
- Doctoral Dissertations (2)
- Electronic Theses and Dissertations (2)
- Honors Program Theses (2)
- Master's Theses (2)
- Publications and Research (2)
- The Summer Undergraduate Research Fellowship (SURF) Symposium (2)
- Amit Singh (1)
- Biochemistry and Molecular Medicine Faculty Publications (1)
- Bioelectrics Publications (1)
- Biological Sciences Faculty Publications (1)
- Biology Department Faculty Works (1)
- Biology Faculty publications (1)
- Biomolecular Research Center Publications and Presentations (1)
- Brian S Dorr (1)
- Chemistry & Biochemistry Faculty Works (1)
- DePaul Discoveries (1)
- Department of Biological Sciences Publications (1)
- Dissertations (1)
- Electronic Thesis and Dissertation Repository (1)
- FIU Electronic Theses and Dissertations (1)
- Publication Type
- File Type
Articles 91 - 98 of 98
Full-Text Articles in Biochemistry, Biophysics, and Structural Biology
Constitutive Activity In Orphan G Protein Coupled Receptors, Adam Lee Martin
Constitutive Activity In Orphan G Protein Coupled Receptors, Adam Lee Martin
Doctoral Dissertations
"The goal of this research was to use a distal signaling pathway analysis to evaluate the extent of agonist independent constitutive signaling among orphan class-A G protein coupled receptors (GPCRs). These receptors translate extracellular signals via conformational change into intracellular activation of different G proteins and subsequent second messenger synthesis. These small molecules regulate cellular biochemistry, eventually leading to nuclear signaling that results in changes in gene expression. Some GPCRs are capable of signaling in the absence of an activating ligand, a phenomenon called constitutive activity that is inhibited via an "inverse-agonist". The use of cAMP dependent Luciferase expression is …
Purification And Characterization Of Bcsc; An Integral Component Of Bacterial Cellulose Export, Emily D. Wilson Ms
Purification And Characterization Of Bcsc; An Integral Component Of Bacterial Cellulose Export, Emily D. Wilson Ms
Theses and Dissertations (Comprehensive)
Biofilms are a growing concern in the medical field due to their increased resistance to antibiotics. When found in a biofilm, bacteria can have antibiotic resistance 10-1000 times that of their planktonic counterparts. Therefore, it is important to study the formation of biofilms. Cellulose biofilms are formed by Enterobacteriaceae, such as many Escherichia coli and Salmonella spp. strains. Biofilms provide these species with benefits including antimicrobial protection, development of bacterial communities, promotion of DNA exchange, uptake of nutrients, and, in the case of cellulose biofilms, immune system evasion. Cellulose biofilms are controlled by the Bacterial cellulose synthesis (Bcs) complex located …
Editors' Note, Laura B. Regassa, Delena Gatch
Editors' Note, Laura B. Regassa, Delena Gatch
Department of Biology Faculty Publications
Dear colleagues,
The International Journal for the Scholarship of Teaching & Learning is undergoing some major changes.
- The layout of the journal has been overhauled, giving it a look that better aligns with the quality of the content. As we continue to struggle with SoTL “counting” as scholarship at some institutions, it is important to package our work in a way that reinforces its value. We hope you enjoy the new look!
- Articles are being assigned DOI (digital object identifier) numbers. All articles, past and present, will be tagged and linked to metadata as indexing is completed over the next …
Functional Analysis Of The Ovarian Cancer Susceptibility Locus At 9p22.2 Reveals A Transcription Regulatory Network Mediated By Bnc2 In Ovarian Cells, Melissa Buckley
Functional Analysis Of The Ovarian Cancer Susceptibility Locus At 9p22.2 Reveals A Transcription Regulatory Network Mediated By Bnc2 In Ovarian Cells, Melissa Buckley
USF Tampa Graduate Theses and Dissertations
GWAS have identified several chromosomal loci associated with ovarian cancer risk. However, the mechanism underlying these associations remains elusive. We identify candidate functional Single Nucleotide Polymorphisms (SNPs) at the 9p22.2 ovarian cancer susceptibility locus, several of which map to transcriptional regulatory elements active in ovarian cells identified by FAIRE-seq (Formaldehyde assisted isolation of regulatory elements followed by sequencing) and ChIP-seq (Chromatin Immunoprecipitation followed by sequencing) in relevant cell types. Reporter and electrophoretic mobility shift assays (EMSA) determined the extent to which candidate SNPs had allele specific effects. Chromosome conformation capture (3C) reveals a physical association between Basonuclin 2 (BNC2) and …
High-Throughput Screening Of Age-Related Changes In Caenorhabditis Elegans, Neil Copes
High-Throughput Screening Of Age-Related Changes In Caenorhabditis Elegans, Neil Copes
USF Tampa Graduate Theses and Dissertations
This project was developed to identify novel methods for high-throughput culturing and screening of C. elegans to investigate age-related metabolic changes and to survey the proteomic and metabolomic factors associated with age-related changes. To accomplish these goals we developed a novel way to grow C. elegans in liquid culture in 96-well microplates for several weeks without suffering significant fluid loss due to evaporation and without needing to shake or unseal the plates for aeration. We also developed methods for assaying the total volume of live C. elegans in microplate cultures using a fluorescence microplate reader and for performing RNAi experiments …
The Effects Of Supplemented Metabolites On Lifespan And Stress Response Pathways In Caenorhabditis Elegans, Clare B. Edwards
The Effects Of Supplemented Metabolites On Lifespan And Stress Response Pathways In Caenorhabditis Elegans, Clare B. Edwards
USF Tampa Graduate Theses and Dissertations
Understanding how metabolites contribute to anaplerosis, antioxidant effects, and hormetic pathways during aging is fundamental to creating supplements and dietary habits that may decrease age-associated disease and decline, thus improving the quality of life in old age. In order to uncover metabolic pathways that delay aging, the effects of large sets of metabolites associated with mitochondrial function on lifespan were investigated.
Malate, the tricarboxylic acid (TCA) cycle metabolite, increased lifespan and thermotolerance in C. elegans. Addition of fumarate and succinate also extended lifespan and all three metabolites activated nuclear translocation of the cytoprotective DAF-16/FOXO transcription factor and protected from paraquat-induced …
Shifting The Stress Curve: Using "Stress Inoculation" And Exercise To Promote Resilience, Mikyung Kim
Shifting The Stress Curve: Using "Stress Inoculation" And Exercise To Promote Resilience, Mikyung Kim
Master's Theses
Problem
Stress influences an organism’s physiological systems via an inverted u-shaped curve: An optimum amount of stress will optimize body functions, but too little stress or too much stress for long periods of time can impair body functions. Researchers have been very interested in exploring the mechanisms that may “delay the tipping point” between the positive and negative effects of stress. A rightward shift in the stress curve would allow one to maintain optimal performance even at higher or more prolonged stress levels. The molecular and cellular mechanisms that underlie this rightward shift could result in resilience, clinically defined as …
Non-Destructive Dna Extraction Methods That Yield Dna Barcodes In Spiders, Reva Ann Bork
Non-Destructive Dna Extraction Methods That Yield Dna Barcodes In Spiders, Reva Ann Bork
Honors Program Theses
DNA barcodes are short sequences of nucleotides that differ from species to species (Hebert et al., 2003; Hebert & Gregory, 2005). DNA barcoding is very important in helping to reconstruct phylogenetic trees and to confirm the identity of threatened or endangered species in the wild. Additionally, it has become increasingly popular in the food industry to test the accuracy of the food being sold in fast food chains (Wong and Hanner, 2008). For scientific purposes, nondestructive DNA extraction techniques need to be explored because they allow for preservation of the voucher specimen, which is particularly important for rare or extinct …