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Full-Text Articles in Other Animal Sciences
Physiological And Behavioural Evaluation Of Common Anaesthesia Practices In The Rainbow Trout, Kieran C. Pounder, Jennifer L. Mitchell, Jack S. Thomson, Tom G. Pottinger, Lynne U. Sneddon
Physiological And Behavioural Evaluation Of Common Anaesthesia Practices In The Rainbow Trout, Kieran C. Pounder, Jennifer L. Mitchell, Jack S. Thomson, Tom G. Pottinger, Lynne U. Sneddon
Lynne Sneddon, PhD
Anaesthetic drugs are commonly administered to fish in aquaculture, research and veterinary contexts. Anaesthesia causes temporary absence of consciousness and may reduce the stress and/or pain associated with handling and certain invasive procedures. The rainbow trout (Oncorhynchus mykiss) is a widely-used model species with relevance to both aquaculture and natural ecosystems. This study sought to establish the relative acute impact of commonly used anaesthetics on rainbow trout when used for anaesthesia or euthanasia by exploring their effects on aversion behaviour and stress physiology. Five widely used anaesthetics were investigated at two concentrations reflective of common laboratory practises: MS-222, benzocaine, 2-phenoxyethanol, …
Reduction In Activity By Noxious Chemical Stimulation Is Ameliorated By Immersion In Analgesic Drugs In Zebrafish, Javier Lopez-Luna, Qussay Al-Jubouri, Waleed Al-Nuaimy, Lynne U. Sneddon
Reduction In Activity By Noxious Chemical Stimulation Is Ameliorated By Immersion In Analgesic Drugs In Zebrafish, Javier Lopez-Luna, Qussay Al-Jubouri, Waleed Al-Nuaimy, Lynne U. Sneddon
Lynne Sneddon, PhD
Research has recently demonstrated that larval zebrafish show similar molecular responses to nociception to those of adults. Our study explored whether unprotected larval zebrafish exhibited altered behaviour after exposure to noxious chemicals and screened a range of analgesic drugs to determine their efficacy to reduce these responses. This approach aimed to validate larval zebrafish as a reliable replacement for adults as well as providing a high-throughput means of analysing behavioural responses. Zebrafish at 5 days postfertilization were exposed to known noxious stimuli: acetic acid (0.01%, 0.1% and 0.25%) and citric acid (0.1%, 1% and 5%). The behavioural response of each …
Impact Of Stress, Fear And Anxiety On The Nociceptive Responses Of Larval Zebrafish, Javier Lopez-Luna, Qussay Al-Jubouri, Lynne U. Sneddon
Impact Of Stress, Fear And Anxiety On The Nociceptive Responses Of Larval Zebrafish, Javier Lopez-Luna, Qussay Al-Jubouri, Lynne U. Sneddon
Lynne Sneddon, PhD
Both adult and larval zebrafish have been demonstrated to show behavioural responses to noxious stimulation but also to potentially stress- and fear or anxiety- eliciting situations. The pain or nociceptive response can be altered and modulated by these situations in adult fish through a mechanism called stress-induced analgesia. However, this phenomenon has not been described in larval fish yet. Therefore, this study explores the behavioural changes in larval zebrafish after noxious stimulation and exposure to challenges that can trigger a stress, fear or anxiety reaction. Five-day post fertilization zebrafish were exposed to either a stressor (air emersion), a predatory fear …
Do Painful Sensations And Fear Exist In Fish?, Lynne U. Sneddon
Do Painful Sensations And Fear Exist In Fish?, Lynne U. Sneddon
Lynne Sneddon, PhD
The detection of pain and fear in fi sh has been subject to much debate and, since fi sh are a popular experimental model and commercially important in both angling and aquaculture, many procedures that fi sh are subjected to cause injury, fear and stress. These injuries would give rise to the sensation of pain in humans but whether fi sh have the capacity for pain is relatively under explored. Recent evidence has shown that fi sh have the same neural apparatus to detect pain that mammals and humans do, that their brain is active during a potentially painful experience, …