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Articles 1 - 5 of 5
Full-Text Articles in Other Animal Sciences
Transgenesis In Animal Agriculture: Addressing Animal Health And Welfare Concerns, Michael Greger
Transgenesis In Animal Agriculture: Addressing Animal Health And Welfare Concerns, Michael Greger
Michael Greger, MD, FACLM
The US Food and Drug Administration’s final Guidance for Industry on the regulation of transgenesis in animal agriculture has paved the way for the commercialization of genetically engineered (GE) farm animals. The production-related diseases associated with extant breeding technologies are reviewed, as well as the predictable welfare consequences of continued emphasis on prolificacy at the potential expense of physical fitness. Areas in which biotechnology could be used to improve the welfare of animals while maintaining profitability are explored along with regulatory schema to improve agency integration in GE animal oversight.
The Human/Animal Interface: Emergence And Resurgence Of Zoonotic Infectious Diseases, Michael Greger
The Human/Animal Interface: Emergence And Resurgence Of Zoonotic Infectious Diseases, Michael Greger
Michael Greger, MD, FACLM
Emerging infectious diseases, most of which are considered zoonotic in origin, continue to exact a significant toll on society. The origins of major human infectious diseases are reviewed and the factors underlying disease emergence explored. Anthropogenic changes, largely in land use and agriculture, are implicated in the apparent increased frequency of emergence and reemergence of zoonoses in recent decades. Special emphasis is placed on the pathogen with likely the greatest zoonotic potential, influenzavirus A.
Amyloid Fibrils: Potential Food Safety Implications, Michael Greger
Amyloid Fibrils: Potential Food Safety Implications, Michael Greger
Michael Greger, MD, FACLM
The demonstration of oral Amyloid-A (AA) fibril transmissibility has raised food safety questions about the consumption of amyloidotic viscera. In a presumed prion-like mechanism, amyloid fibrils have been shown to trigger and accelerate the development of AA amyloidosis in rodent models. The finding of amyloid fibrils in edible avian and mammalian food animal tissues, combined with the inability of cooking temperatures to eliminate their amyloidogenic potential, has led to concerns that products such as pâté de foie gras may activate a reactive systemic amyloidosis in susceptible consumers. Given the ability of amyloid fibrils to cross-seed the formation of chemically heterologous …
Their Bugs Are Worse Than Their Bite: Emerging Infectious Disease And The Human-Animal Interface, Michael Greger
Their Bugs Are Worse Than Their Bite: Emerging Infectious Disease And The Human-Animal Interface, Michael Greger
Michael Greger, MD, FACLM
In the twenty-five years since that announcement, what we now know as AIDS has killed 20 million people (National AIDS Trust 2005). Where did the AIDS virus— and other emerging diseases, such as severe acute respiratory syndrome (SARS), Ebola, mad cow— come from?
Trait Selection And Welfare Of Genetically Engineered Animals In Agriculture, Michael Greger
Trait Selection And Welfare Of Genetically Engineered Animals In Agriculture, Michael Greger
Michael Greger, MD, FACLM
The release of the Final Guidance from the US Food and Drug Administration on the commercialization of genetically engineered animals has sparked renewed discussion over the ethical, consumer, and regulatory implications of transgenesis in animal agriculture. Animal welfare critiques have focused on unexpected phenotypic effects in animals used in transgenic research, rather than on the health and welfare implications of the intended productivity enhancement. Unless breeding goals are redefined to reflect social concerns, the occurrence and magnitude of undesirable side effects may increase and consumer confidence in the nascent technology may be undermined.