Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 1 of 1
Full-Text Articles in Dairy Science
Bovine Mammary Interleukin-8 Receptor Expression And Genetic Association With Streptococcus Uberis Based Mastitis., Lydia Jean Siebert
Bovine Mammary Interleukin-8 Receptor Expression And Genetic Association With Streptococcus Uberis Based Mastitis., Lydia Jean Siebert
Masters Theses
Mastitis is an economically distressing disease in the dairy industry. Bacterial pathogens enter the gland and encounter cell types that release immune mediators including interleukin (IL)-8. IL-8 has two membrane bound receptors: CXCR1 and CXCR2. CXCR1 and CXCR2 are expressed on neutrophils and other cell types in other species but their expression is unknown in the bovine mammary gland. To test this, mammary tissue samples from six Holstein dairy cows were subject to dual immunofluorescence with bovine specific CXCR1 and CXCR2 antibodies and cell type markers. CXCR1 was expressed on alveolar epithelial cells, fibroblasts, and leukocytes. CXCR2 expression was identified …