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Life Sciences Commons

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2020

Virginia Commonwealth University

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Articles 31 - 60 of 108

Full-Text Articles in Life Sciences

A Mathematical Model To Explore The Potential Of Combinations Of Adt And Immunotherapies, Johnna Barnaby May 2020

A Mathematical Model To Explore The Potential Of Combinations Of Adt And Immunotherapies, Johnna Barnaby

Biology and Medicine Through Mathematics Conference

No abstract provided.


Modelling The Evolution Of Barrier Islands, Greg Robson May 2020

Modelling The Evolution Of Barrier Islands, Greg Robson

Biology and Medicine Through Mathematics Conference

No abstract provided.


The Role Of Repeat Infection In The Dynamics Of A Simple Model Of Waning And Boosting Immunity, Laura F. Strube, Maya Walton, Lauren M. Childs May 2020

The Role Of Repeat Infection In The Dynamics Of A Simple Model Of Waning And Boosting Immunity, Laura F. Strube, Maya Walton, Lauren M. Childs

Biology and Medicine Through Mathematics Conference

No abstract provided.


A Mathematical Framework To Augment Metrics Of Small Intestinal Health, Cara J. Sulyok, Judy Day, Suzanne Lenhart May 2020

A Mathematical Framework To Augment Metrics Of Small Intestinal Health, Cara J. Sulyok, Judy Day, Suzanne Lenhart

Biology and Medicine Through Mathematics Conference

No abstract provided.


Eco-Evolutionary Dynamics Of Microbial Communities, Lihong Zhao May 2020

Eco-Evolutionary Dynamics Of Microbial Communities, Lihong Zhao

Biology and Medicine Through Mathematics Conference

No abstract provided.


Parameter Identifiability And Estimation In A 1d Cardiovascular Fluid Dynamics Model, Mitchel J. Colebank May 2020

Parameter Identifiability And Estimation In A 1d Cardiovascular Fluid Dynamics Model, Mitchel J. Colebank

Biology and Medicine Through Mathematics Conference

No abstract provided.


Effects Of Slip On Highly Viscous Thin-Film Flows Inside A Vertical Tube, Mark S. Schwitzerlett May 2020

Effects Of Slip On Highly Viscous Thin-Film Flows Inside A Vertical Tube, Mark S. Schwitzerlett

Biology and Medicine Through Mathematics Conference

No abstract provided.


Emergence, Mechanics, And Development: How Behavior And Geometry Underlie Cowrie Seashell Form, Michael G. Levy, Michael R. Deweese May 2020

Emergence, Mechanics, And Development: How Behavior And Geometry Underlie Cowrie Seashell Form, Michael G. Levy, Michael R. Deweese

Biology and Medicine Through Mathematics Conference

No abstract provided.


Mathematical Modeling Of The Car T-Cell Therapy, Emek Kose, Elizabeth Zollinger, Samantha Elliott May 2020

Mathematical Modeling Of The Car T-Cell Therapy, Emek Kose, Elizabeth Zollinger, Samantha Elliott

Biology and Medicine Through Mathematics Conference

No abstract provided.


In Silico Mouse Model Of Infection And Immunity, Daniel Jonas, Michael Kirby, Alan R. Schenkel May 2020

In Silico Mouse Model Of Infection And Immunity, Daniel Jonas, Michael Kirby, Alan R. Schenkel

Biology and Medicine Through Mathematics Conference

No abstract provided.


Tympanal Asymmetry In A Parasitoid Fly: Small Asymmetries Produce Big Gains, Max Mikel-Stites, Anne E. Staples May 2020

Tympanal Asymmetry In A Parasitoid Fly: Small Asymmetries Produce Big Gains, Max Mikel-Stites, Anne E. Staples

Biology and Medicine Through Mathematics Conference

No abstract provided.


Estimation Of Insulin Sensitivity From Continuous Glucose Monitoring Data During An Intravenous Glucose Tolerance Test, Rachel Jennings, Jonathan Rolfs, Joseph Roxas, James Okusa, Jacqueline Virtudes May 2020

Estimation Of Insulin Sensitivity From Continuous Glucose Monitoring Data During An Intravenous Glucose Tolerance Test, Rachel Jennings, Jonathan Rolfs, Joseph Roxas, James Okusa, Jacqueline Virtudes

Biology and Medicine Through Mathematics Conference

No abstract provided.


Modeling Angiogenesis In Cutaneous Wound Healing, Ephraim Agyingi May 2020

Modeling Angiogenesis In Cutaneous Wound Healing, Ephraim Agyingi

Biology and Medicine Through Mathematics Conference

No abstract provided.


Performance Of Phenomenological Models For Real-Time Forecasting The Covid-19 Epidemic, Kimberlyn Roosa, Gerardo Chowell May 2020

Performance Of Phenomenological Models For Real-Time Forecasting The Covid-19 Epidemic, Kimberlyn Roosa, Gerardo Chowell

Biology and Medicine Through Mathematics Conference

No abstract provided.


Explicit Probability Of Fixation Formula For Mutual Competitors In A Stochastic Population Model Under Competitive Trade-Offs, Glenn Steven Young, Andrew Belmonte May 2020

Explicit Probability Of Fixation Formula For Mutual Competitors In A Stochastic Population Model Under Competitive Trade-Offs, Glenn Steven Young, Andrew Belmonte

Biology and Medicine Through Mathematics Conference

No abstract provided.


A Phosphoinositide-Based Model Of Actin Waves In Frustrated Phagocytosis, Marco A. Avila Ponce De Leon May 2020

A Phosphoinositide-Based Model Of Actin Waves In Frustrated Phagocytosis, Marco A. Avila Ponce De Leon

Biology and Medicine Through Mathematics Conference

No abstract provided.


Parameter Estimation For Tear Film Thinning, Rayanne Luke May 2020

Parameter Estimation For Tear Film Thinning, Rayanne Luke

Biology and Medicine Through Mathematics Conference

No abstract provided.


Geometry-Based Estimates Of Glutamate Transporter Density In Astrocytes, Anca R. Radulescu, Cassandra Williams, Annalisa Scimemi May 2020

Geometry-Based Estimates Of Glutamate Transporter Density In Astrocytes, Anca R. Radulescu, Cassandra Williams, Annalisa Scimemi

Biology and Medicine Through Mathematics Conference

No abstract provided.


Effects Of Local Mutations In Quadratic Iterations, Abraham Longbotham, Anca R. Radulescu May 2020

Effects Of Local Mutations In Quadratic Iterations, Abraham Longbotham, Anca R. Radulescu

Biology and Medicine Through Mathematics Conference

No abstract provided.


The Role Of Variation In Mate Choice And Wolbachia Infection On Aedes Aegypti Population Dynamics, Bernardo Ameneyro May 2020

The Role Of Variation In Mate Choice And Wolbachia Infection On Aedes Aegypti Population Dynamics, Bernardo Ameneyro

Biology and Medicine Through Mathematics Conference

No abstract provided.


Using Network Modeling To Understand The Relationship Between Sars-Cov-1 And Sars-Cov-2, Elizabeth Brooke Haywood, Nicole A. Bruce May 2020

Using Network Modeling To Understand The Relationship Between Sars-Cov-1 And Sars-Cov-2, Elizabeth Brooke Haywood, Nicole A. Bruce

Biology and Medicine Through Mathematics Conference

No abstract provided.


Exploring The Effect Of The Nestling Recruitment Curve On Enzootic West Nile Virus Transmission, Emily B. Horton May 2020

Exploring The Effect Of The Nestling Recruitment Curve On Enzootic West Nile Virus Transmission, Emily B. Horton

Biology and Medicine Through Mathematics Conference

No abstract provided.


An Identification Of Tgf-B'S Role In Ischemic Cholangiopathy, Courtney Chmielewski Jan 2020

An Identification Of Tgf-B'S Role In Ischemic Cholangiopathy, Courtney Chmielewski

Theses and Dissertations

Organ transplants are a necessary intervention for many diseases that result in end stage organ failure. The donation pool cannot match the demands of the transplant list, so expanding the pool to include donation after cardiac death (DCD) is desired. However, there are increased odds of graft failure and ischemic cholangiopathy leading to inferior outcomes when DCD livers are used. Ischemic cholangiopathy consists of multiple diffuse strictures and fibrosis of the bile ducts leading to a loss of epithelialization and fibrosis. The cellular mechanism is proposed to be epithelial-to-mesenchymal transition (EMT). TGF-�� is seen as a key initiator of EMT, …


Senescent Trees Stabilize Aboveground Wood Net Primary Production Immediately After Disturbance, Maxim S. Grigri Jan 2020

Senescent Trees Stabilize Aboveground Wood Net Primary Production Immediately After Disturbance, Maxim S. Grigri

Theses and Dissertations

In the United States, forests sequester 17% of national carbon (C) emissions annually (UGCRP, 2018), however shifting forest disturbances threaten the stability of this essential C sink. Unlike the high severity, stand-replacing disturbances that were widespread a century ago, today’s eastern temperate forests experience frequent low-to-moderate severity disturbances from invasive pests and pathogens with mixed effects on net primary production (NPP). Carbon cycling stability after disturbance has been reported, however, the mechanisms underlying immediate NPP stability or decline are not well understood. Through weekly measurements of production in a landscape scale experiment, we show that the sustained growth of senescent …


Role Of Clic4 And The Synaptic Transcriptome In The Behavioral And Molecular Neurobiology Of Ethanol, Rory M. Weston Jan 2020

Role Of Clic4 And The Synaptic Transcriptome In The Behavioral And Molecular Neurobiology Of Ethanol, Rory M. Weston

Theses and Dissertations

Alcohol use disorder (AUD) is a prevalent neuropsychiatric disease with profound health, social, and economic consequences. With an estimated 50% heritability, identifying genes that engender risk and contribute to the underlying neurobiological mechanisms represents an important first step in developing effective treatments. Gene expression studies are an important source of candidate genes for studying AUD, providing windows into the molecular machinery engaged by the brain in response to ethanol. Published studies have identified chloride intracellular channel 4 (Clic4) as an ethanol-regulated gene in brain capable of modulating sensitivity to sedation in multiple species. The functions of Clic4 are …


Decreased Temperature Variance Associated With Biotic Composition Enhances Coastal Shrub Encroachment, Lauren K. Wood, Spencer Hays, Julie C. Zinnert Jan 2020

Decreased Temperature Variance Associated With Biotic Composition Enhances Coastal Shrub Encroachment, Lauren K. Wood, Spencer Hays, Julie C. Zinnert

Biology Publications

Regime shift from grasslands to shrub-dominated landscapes occur worldwide driven by altered land-use and climate change, affecting landscape function, biodiversity, and productivity. Warming winter temperatures are a main driver of expansion of the native, evergreen shrub, Morella cerifera, in coastal landscapes. Shrub establishment in these habitats alters microclimate, but little is known about seasonal differences and microclimate variance. We assessed influence of shrubs on microclimate variance, community composition, and community physiological functioning across three vegetation zones: grass, transitional, and shrub in a coastal grassland. Using a novel application of a time-series analysis, we interpret microclimatic variance modification and elucidate …


Topography And Disturbance Influence Trait‐Based Composition And Productivity Of Adjacent Habitats In A Coastal System, Joseph K. Brown, Julie C. Zinnert Jan 2020

Topography And Disturbance Influence Trait‐Based Composition And Productivity Of Adjacent Habitats In A Coastal System, Joseph K. Brown, Julie C. Zinnert

Biology Publications

Coastal systems experience frequent disturbance and multiple environmental stressors over short spatial and temporal scales. Investigating functional traits in coastal systems has the potential to inform how variation in disturbance frequency and environmental variables influence differences in trait‐based community composition and ecosystem function. Our goals were to (1) quantify trait‐based communities on two barrier islands divergent in topography and long‐term disturbance response and (2) determine relationships between community trait‐based composition and ecosystem productivity. We hypothesized that locations documented with high disturbance would have habitats with similar environmental conditions and trait‐based communities, with the opposite relationship in low‐disturbance locations. Furthermore, we …


Ovarian Transcriptomic Analyses In The Urban Human Health Pest, The Western Black Widow Spider, Lindsay S. Miles, Nadia A. Ayoub, Jessica E. Garb, Robert A. Haney, Brian C. Verrelli Jan 2020

Ovarian Transcriptomic Analyses In The Urban Human Health Pest, The Western Black Widow Spider, Lindsay S. Miles, Nadia A. Ayoub, Jessica E. Garb, Robert A. Haney, Brian C. Verrelli

Center for Integrative Life Sciences Education Publications

Due to their abundance and ability to invade diverse environments, many arthropods have become pests of economic and health concern, especially in urban areas. Transcriptomic analyses of arthropod ovaries have provided insight into life history variation and fecundity, yet there are few studies in spiders despite their diversity within arthropods. Here, we generated a de novo ovarian transcriptome from 10 individuals of the western black widow spider (Latrodectus hesperus), a human health pest of high abundance in urban areas, to conduct comparative ovarian transcriptomic analyses. Biological processes enriched for metabolism—specifically purine, and thiamine metabolic pathways linked to oocyte …


Non-Destructive, Rapid Differentiation Of Cell Types Relevant To Sexual Assault Investigations Utilizing Morphological And Autofluorescence Signatures, Taylor R. Moldenhauer Jan 2020

Non-Destructive, Rapid Differentiation Of Cell Types Relevant To Sexual Assault Investigations Utilizing Morphological And Autofluorescence Signatures, Taylor R. Moldenhauer

Theses and Dissertations

Current methods for confirming the presence of spermatozoa in sexual assault samples can be time-consuming and often lack sensitivity; however, this remains the most definitive test for the presence of semen. Additionally, male DNA can be deposited without the presence of intact sperm as may be the case with seminal fluid from vasectomized individuals or sexual activity where seminal fluid is not recovered (e.g., perpetrator wears a condom, penetration without ejaculation, etc.). The ability to detect bodily fluids, as well as quantify their presence in a sample, could aid in forensic DNA analysis by limiting the amount of time performing …


The Process And A Pitfall In Developing Biology And Chemistry Problems For Mathematics Courses, Mary Beisiegel, Lori Kayes, Devon Quick, Richard Nafshun, Michael Lopez, Steve Dobrioglo, Michael Dickens Jan 2020

The Process And A Pitfall In Developing Biology And Chemistry Problems For Mathematics Courses, Mary Beisiegel, Lori Kayes, Devon Quick, Richard Nafshun, Michael Lopez, Steve Dobrioglo, Michael Dickens

Journal of Mathematics and Science: Collaborative Explorations

In this paper, we describe our process for developing applied problems from biology and chemistry for use in a differential calculus course. We describe our conversations and curricular analyses that led us to change from our initial focus on college algebra to calculus. We provide results that allowed us to see the overlaps between biology and mathematics and chemistry and mathematics and led to a specific focus on problems related to rates of change. Finally, we investigate the problems that were developed by the partner disciplines for use on recitation activities in calculus and how those problems were modified by …