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2020

Virginia Commonwealth University

Graduate Research Posters

Articles 1 - 5 of 5

Full-Text Articles in Life Sciences

Comparative Morphological Study On The Shape Variance Of The Scapula In Extant Cercopithecidae, Marie Vergamini, Lisa Day Jan 2020

Comparative Morphological Study On The Shape Variance Of The Scapula In Extant Cercopithecidae, Marie Vergamini, Lisa Day

Graduate Research Posters

Morphological variation in forelimb bones has been tied to substrate use in Cercopithecidae. Studies of the distal humerus and proximal ulna (Rector et al., 2018) suggest that African and Asian monkeys’ locomotor repertoires can be distinguished through analysis of variation of the elbow joint. Given that the scapula may be directly involved in weight-bearing during locomotion - similar to the elbow - the relationship between morphological variation and arboreality in the glenoid cavity, acromion, and coracoid process may be analogous. Using a Microscribe, 25 landmarks were collected to capture the shape of the scapula from a sample of 50+ extant …


Characterization Of Cardiovascular Risk Factors People Living With Hiv In A Veteran Population, Veronica Taylor, Joe Castillo, Daniel Tassone Pharmd, Bcps Jan 2020

Characterization Of Cardiovascular Risk Factors People Living With Hiv In A Veteran Population, Veronica Taylor, Joe Castillo, Daniel Tassone Pharmd, Bcps

Graduate Research Posters

Background: CVD is the leading cause of death in PLWH. HIV positive individuals have a 1.5-2-fold greater risk of CVD compared to uninfected individuals, even if complete viral load suppression is achieved. HIV-associated CVD has tripled over the past 20 years, yet scant data is available describing this population. We have characterized CVD risk factors and treatment in PLWH in order to assess and improve cardioprotective treatment.

Methods: A retrospective EMR review was conducted for HIV positive patients enrolled at the McGuire VAMC between 12/2018 and 12/2019. Patients were excluded if labs were older than one year from follow-up. …


Metal-Oxide Nanostructures Fabricated From Laser-Assisted Synthesis Technique, Mallory John, Katharine M. Tibbetts Jan 2020

Metal-Oxide Nanostructures Fabricated From Laser-Assisted Synthesis Technique, Mallory John, Katharine M. Tibbetts

Graduate Research Posters

Background

Rising levels of greenhouse gases in our atmosphere such as CO 2 are contributing to global rises in temperature, acidification of the oceans, and more extreme weather conditions. Hydrogenation of CO 2 to form carbon-based products is of great importance to reduce CO 2 levels and generate carbon-based compounds that can be used for industrial purposes. Copper- and nickel- based nanocatalysts have promising catalytic activity toward CO 2 hydrogenation, and have great interest to replace expensive and rare Pt- and Pd-based catalysts.

Methods

Focusing high powered laser pulses onto the surface of a silicon wafer immersed in liquid solutions …


Multilevel Variance Components And Brain Volume Mediation Of Life Stress On Post-Traumatic Stress Disorder Symptoms In Children Via Regularization, Daniel Bustamante, Michael C. Neale Jan 2020

Multilevel Variance Components And Brain Volume Mediation Of Life Stress On Post-Traumatic Stress Disorder Symptoms In Children Via Regularization, Daniel Bustamante, Michael C. Neale

Graduate Research Posters

Alterations of volume in brain regions of interest (ROIs) are associated with post-traumatic stress disorder (PTSD). Most of the extant neuroimaging research in PTSD has studied adults. The present study extends this research by using data from children (N=11,869, M age =9.92) from the ABCD study, a multisite longitudinal long-term study of brain development and childhood health in the U.S. Traumatic events (TEs) and PTSD symptoms were measured through the K- SADS for DSM-5. Values of brain ROIs were assessed using structural MRI measures. The unidirectional model was able to detect the small differences from site variance in sMRI mediators …


Zebrafish Model Of Mll-Rearranged Acute Myeloid Leukemia, Alex Belt, Seth J. Corey, Steven Grant, Robert M. Tombes, Sarah C. Rothschild Jan 2020

Zebrafish Model Of Mll-Rearranged Acute Myeloid Leukemia, Alex Belt, Seth J. Corey, Steven Grant, Robert M. Tombes, Sarah C. Rothschild

Graduate Research Posters

Background: Acute myeloid leukemia (AML) is the second most common type of leukemia. Standard treatment includes chemotherapy as well as stem cell transplantation, but for aging patients and those with impaired immune function these rigorous therapies are not always possible. Furthermore, AML patients harboring a chromosomal rearrangement involving Multiple Lineage Leukemia (MLL) exhibit far worse prognoses than patients without. Given these circumstances new therapies must be developed.

Methods: Danio rerio (zebrafish) has emerged as a powerful model organism for investigating human blood malignancies due to the conservation of hematopoiesis between humans and zebrafish. We developed a transient transgenic model exhibiting …