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Full-Text Articles in Life Sciences
Distant Metastasis Of Locally Controlled Supraglottic Laryngeal Carcinoma: A Report Of Two Cases, Charles N. Ford, William W. Finch, Roger W. Kwong
Distant Metastasis Of Locally Controlled Supraglottic Laryngeal Carcinoma: A Report Of Two Cases, Charles N. Ford, William W. Finch, Roger W. Kwong
Henry Ford Hospital Medical Journal
Two cases of supraglottic laryngeal carcinoma are presented in which distant metastasis occurred after adequate local control had been established. The metastasizing tendency of this lesion is discussed, and the efficacy of combined therapeutic approaches in treating these cases is questioned. Submitted
Refractory Hypercalcemia In Sarcoidosis: Exacerbation By Thiazide Diuretics, Differentiation From Primary Hyperparathyroidism, And Possible Role Of Prolactin, A. M. Parfitt
Henry Ford Hospital Medical Journal
Hypercalcemia in a patient with sarcoidosis was made worse by a thiazide diuretic initially given to control hypercalciuria alone. The hypercalcemia was unusually resistant to corticosteroid treatment during the summer even after the thiazide diuretic had been discontinued. Lack of response to corticosteroid together with decreased tubular reabsorption of phosphate and increased tubular reabsorption of calcium suggested associated primary hyperparathyroidism, but PTH was undetectable by immunoassay, and nephrogenous cyclic AMP excretion was zero. Amenorrhea, galactorrhea and hyperprolactinemia were found to be due to a pituitary tumor which was removed. The experience with this patient suggests that: 1) exacerbation of hypercalcemia …
Intracardiac Phonocardiography In Subaortic Stenosis, Paul D. Stein, Hani N. Sabbah, Daniel T. Anbe, Fareed Khaja, Gordon M. Folger Jr.
Intracardiac Phonocardiography In Subaortic Stenosis, Paul D. Stein, Hani N. Sabbah, Daniel T. Anbe, Fareed Khaja, Gordon M. Folger Jr.
Henry Ford Hospital Medical Journal
The purpose of this study is to explore the value of intracardiac sound recordings for the verification of subaortic stenosis. Intracardiac sound was measured in ten patients with subaortic obstructions. Seven had idiopathic hypertrophic subaortic stenosis, two had a subvalvular membrane, and one had a subvalvular tunnel. In each patient, a systolic murmur was recorded within the left ventricle distal to the obstruction. The murmur was of lower amplitude distal to the aortic valve, and it was of even lower amplitude or absent proximal to the obstruction. In the presence of entrapment, no intraventricular murmur occurred although an apparent subvalvular …
Clinical Notes: Bacteremia Associated With Colonoscopy, A. Suarez, B. Schuman, E. Quinn, T. Neblett
Clinical Notes: Bacteremia Associated With Colonoscopy, A. Suarez, B. Schuman, E. Quinn, T. Neblett
Henry Ford Hospital Medical Journal
Twenty-eight patients had a total of 168 blood cultures before and at regular intervals during colonoscopy. No bacteremia was found. Based on our results and other reports, we recommend antibiotic prophylaxis during colonoscopy only for those patients with prosthetic heart valves and for those with valvular heart disease who also have advanced liver disease.
Effect Of Glucagon And Methylprednisolone On Pancreatectomized Recipients Of Whole Pancreas Allografts, Luis H. Toledo-Pereyra, Michael Zammit, Krishna D. Valjee
Effect Of Glucagon And Methylprednisolone On Pancreatectomized Recipients Of Whole Pancreas Allografts, Luis H. Toledo-Pereyra, Michael Zammit, Krishna D. Valjee
Henry Ford Hospital Medical Journal
Glucagon alone or in combination with methylprednisolone was an adequate therapeutic adjuvant for pancreatectomized recipients of whole pancreas allografts. All recipients were minimally immunosuppressed with azathioprine, 5.0 mg/K/day for three days, then 2.5 mg/K/day. The morphological, functional, and survival response after whole pancreas transplantation indicated a trend of improvement in the treated groups. Only the groups of dogs receiving glucagon alone or in combination with methylprednisolone survived more than two weeks after transplantation. This therapy has proven to be effective for whole pancreas transplantation.
Length Of Perfusion Time In Cadaver Kidney Transplantation, Krishna D. Valjee, Luis H. Toledo-Pereyra, Stanley G. Dienst, Cosme Cruz, Pedro Cortes, Godofredo Santiago, Nathan W. Levin, Riad Farah, Joseph C. Cerny
Length Of Perfusion Time In Cadaver Kidney Transplantation, Krishna D. Valjee, Luis H. Toledo-Pereyra, Stanley G. Dienst, Cosme Cruz, Pedro Cortes, Godofredo Santiago, Nathan W. Levin, Riad Farah, Joseph C. Cerny
Henry Ford Hospital Medical Journal
The results of transplantation survival for 70 consecutive cadaver kidneys preserved under hypothermic pulsatile perfusion at Henry Ford Hospital are reviewed. Pulsatile perfusion for up to 30 hours did not adversely alter the survival rate following transplantation. Thus, kidneys perfused for prolonged periods of time (> 20 hours) can be used for transplantation, if the basic rules for organ retrieval and preservation have been followed. Hypothermic pulsatile perfusion of cadaver kidneys has been demonstrated to be an adequate system for ex-vivo preservation for transplantation.
1977 Publications Of The Staff Of Henry Ford Hospital
1977 Publications Of The Staff Of Henry Ford Hospital
Henry Ford Hospital Medical Journal
No abstract provided.
The Quantitative Determination Of 3-Oxo-Bile Acids, W. T. Beher, G. J. Lin, J. Sanfield, S. Stradnieks
The Quantitative Determination Of 3-Oxo-Bile Acids, W. T. Beher, G. J. Lin, J. Sanfield, S. Stradnieks
Henry Ford Hospital Medical Journal
A new method for the rapid quantification of 3-oxo-bile acids has been developed. From 5 to 120 μg of oxo-acid in aqueous or ethanolic media are reduced with sodium borohydride. The resulting 3α- and 3β-hydroxy acids are then oxidized in a reaction catalyzed by 3-hydroxysteroid dehydrogenase, during which nicotinamide adenine dinucleotide (NAD) is reduced to NADH. The absorbance of the reaction mixture is determined at 340 nm and is directly proportional to the amount of 3-oxo-acid in the original sample. The method is fully compatible with that used in determining 3α-hydroxy-bile acids.
Effect Of Perfusate Osmolarity On Hearts Preserved Under Hypothermic Pulsatile Perfusion For 24 Hours, Luis H. Toledo-Pereya, Manuel Chee, Richard C. Lillehei
Effect Of Perfusate Osmolarity On Hearts Preserved Under Hypothermic Pulsatile Perfusion For 24 Hours, Luis H. Toledo-Pereya, Manuel Chee, Richard C. Lillehei
Henry Ford Hospital Medical Journal
Canine hearts preserved under hypothermic pulsatile perfusion (24 hours) with an osmolarity of 340 mOsm/L had better preservation and transplantation response than hearts perfused at an osmolarity of 310 and 270 mOsm/L. The hearts perfused at 340 mOsm /L survived an average of 22.6 days after transplantation. This survival was significantly (p>0.05) better than that observed after fresh transplantation (13.4 days average). Hearts perfused at 270 mOsm /L had a significantly (p>0.05) lower survival after transplantation (5.8 days average) than the fresh allografts or the hearts perfused at 310 or 340 mOsm / L. Similar survival times were …
Chondrosarcoma: A Report Of 65 Cases, Kent K. Wu, Edwin R. Guise, Harold M. Frost, C. Leslie Mitchell
Chondrosarcoma: A Report Of 65 Cases, Kent K. Wu, Edwin R. Guise, Harold M. Frost, C. Leslie Mitchell
Henry Ford Hospital Medical Journal
A statistical analysis is presented of 65 cases of chondrosarcoma treated at Henry Ford Hospital from 1916 to 1976, with adequate follow-up data.
Retroperitoneal Ganglioneuroma: A Case Report And Review Of Literature, Mohammed R. Ansari, Vellore Ramakrishnan, K. S. Rajan
Retroperitoneal Ganglioneuroma: A Case Report And Review Of Literature, Mohammed R. Ansari, Vellore Ramakrishnan, K. S. Rajan
Henry Ford Hospital Medical Journal
Ganglioneuroma, a tumor of neural crest origin, is a rare neoplasm; to encounter it in an adult over 50 years of age is very rare. This report describes the case of a 56-year-old man who was seen at Henry Ford Hospital with an abdominal mass confirmed as ganglioneuroma on histopathology. Experience at Henry Ford Hospital and the available literature on the subject are reviewed.
Studies On Uveitis Part Ii: Hypotheses With Case Reports, Philip C. Hessburg
Studies On Uveitis Part Ii: Hypotheses With Case Reports, Philip C. Hessburg
Henry Ford Hospital Medical Journal
A number of patients with and without uveitis are used to show that this study of aqueous microbiology suggests the following hypotheses: 1. Routine techniques currently used in most microbiology laboratories overlook classical and variant bacteria which might be isolated from clinical specimens with improved microbiological techniques. 2. Bacterial forms may be present in other ocular tissue when not present in the aqueous. 3. Polymicrobial infections probably occur rather frequently, especially in chronic or subacute inflammatory states. 4. Alterations in various host factors may subject some persons to a greater incidence of inflammatory episodes including uveitis. 5. Antibiotics used in …