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Articles 1 - 30 of 142
Full-Text Articles in Life Sciences
"23 And Plea": Limiting Police Use Of Genealogy Sites After Carpenter V. United States, Antony Barone Kolenc
"23 And Plea": Limiting Police Use Of Genealogy Sites After Carpenter V. United States, Antony Barone Kolenc
West Virginia Law Review
No abstract provided.
Associations Of Adiposity And Diet Quality With Serum Ceramides In Middle-Aged Adults With Cardiovascular Risk Factors, Margaret A. Drazba, Ida Holaskova, Nadine R. Sahyoun, Melissa Ventura Marra
Associations Of Adiposity And Diet Quality With Serum Ceramides In Middle-Aged Adults With Cardiovascular Risk Factors, Margaret A. Drazba, Ida Holaskova, Nadine R. Sahyoun, Melissa Ventura Marra
Faculty & Staff Scholarship
Rates of adverse cardiovascular events have increased among middle-aged adults. Elevated ceramides have been proposed as a risk factor for cardiovascular events. Diet quality and weight status are inversely associated with several traditional risk factors; however, the relationship to ceramides is less clear. This study aimed to determine associations of adiposity and diet quality with circulating ceramides in middle-aged adults (n = 96). Diet quality was estimated using the Healthy Eating Index 2015 (HEI-2015). Serum ceramide concentrations were determined by liquid chromatography–mass spectrometry. A ceramide risk score was determined based on ceramides C16:0, C18:0, and C24:1 and their ratios to …
Cooking And Meal Planning As Predictors Of Fruit And Vegetable Intake And Bmi In First-Year College Students, Andrea J. Hanson, Kendra K. Kattleman, Lacey A. Mccormack, Wenjun Zhou, Onikia N. Brown, Tanya M. Horacek, Karla P. Shelnutt, Tandalayo Kidd, Audrey Opoku-Acheampong, Lisa D. Franzen-Castle, Melissa D. Olfert, Sarah E. Colby
Cooking And Meal Planning As Predictors Of Fruit And Vegetable Intake And Bmi In First-Year College Students, Andrea J. Hanson, Kendra K. Kattleman, Lacey A. Mccormack, Wenjun Zhou, Onikia N. Brown, Tanya M. Horacek, Karla P. Shelnutt, Tandalayo Kidd, Audrey Opoku-Acheampong, Lisa D. Franzen-Castle, Melissa D. Olfert, Sarah E. Colby
Faculty & Staff Scholarship
The objective was to determine if cooking skills and meal planning behaviors are associated with greater fruit and vegetable intake and lower body mass index (BMI) in first-year college students who are at risk for excessive weight gain. A cross-sectional analysis was conducted using baseline data from a multi-state research project aimed at preventing weight gain in first-year college students. Cooking type, frequency and confidence, self-instruction for healthful mealtime behavior intention, self-regulation of healthful mealtime behavior, and cup equivalents of fruits and vegetables (FV) were measured using validated surveys. BMI was calculated from measured height and weight. First-year students (n …
Neural Processing Of Communication Signals: The Extent Of Sender–Receiver Matching Varies Across Species Of Apteronotus, Kathryne M. Allen, Gary Marsat
Neural Processing Of Communication Signals: The Extent Of Sender–Receiver Matching Varies Across Species Of Apteronotus, Kathryne M. Allen, Gary Marsat
Faculty & Staff Scholarship
As communication signal properties change, through genetic drift or selective pressure, the sensory systems that receive these signals must also adapt to maintain sensitivity and adaptability in an array of contexts. Shedding light on this process helps us to understand how sensory codes are tailored to specific tasks. In a species of weakly electric fish, Apteronotus albifrons, we examined the unique neurophysiological properties that support the encoding of electrosensory communication signals that the animal encounters in social exchanges. We compare our findings to the known coding properties of the closely related species Apteronotus leptorhynchus to establish how these animals …
Choice Architecture In Appalachian High Schools: Evaluating And Improving Cafeteria Environments, Melissa D. Olfert, Rebecca L. Hagedorn, Emily N. Clegg, Shannon Ackerman, Cheryl Brown
Choice Architecture In Appalachian High Schools: Evaluating And Improving Cafeteria Environments, Melissa D. Olfert, Rebecca L. Hagedorn, Emily N. Clegg, Shannon Ackerman, Cheryl Brown
Faculty & Staff Scholarship
School meals are a primary source of nutrition for many adolescents. Determining factors that influence the selection of various foods can provide insight on strategies to improve students’ cafeteria choices. This evaluation and observation was conducted at three Appalachian high schools to assess the cafeteria environment. The study developed and implemented an assessment tool created using principles of choice architecture and behavioral economics building on the work of the Cornell Center for Behavioral Economics in Child Nutrition Programs (BEN Center). The assessment tool scored eight components of the lunchroom—the exterior, hot serving area, cold serving area, salad bar, beverage area, …
The Nac Family Transcription Factor Gmnac42–1 Regulates Biosynthesis Of The Anticancer And Neuroprotective Glyceollins In Soybean, Md Asraful Jahan, Brianna Harris, Matthew Lowery, Katie Coburn, Aniello M. Infante, Ryan J. Percifield, Amanda G. Ammer, Nik Kovinich
The Nac Family Transcription Factor Gmnac42–1 Regulates Biosynthesis Of The Anticancer And Neuroprotective Glyceollins In Soybean, Md Asraful Jahan, Brianna Harris, Matthew Lowery, Katie Coburn, Aniello M. Infante, Ryan J. Percifield, Amanda G. Ammer, Nik Kovinich
Faculty & Staff Scholarship
Background
Glyceollins are isoflavonoid-derived pathogen-inducible defense metabolites (phytoalexins) from soybean (Glycine max L. Merr) that have important roles in providing defense against pathogens. They also have impressive anticancer and neuroprotective activities in mammals. Despite their potential usefulness as therapeutics, glyceollins are not economical to synthesize and are biosynthesized only transiently and in low amounts in response to specific stresses. Engineering the regulation of glyceollin biosynthesis may be a promising approach to enhance their bioproduction, yet the transcription factors (TFs) that regulate their biosynthesis have remained elusive. To address this, we first aimed to identify novel abiotic stresses that enhance …
Educational Intervention Improves Fruit And Vegetable Intake In Young Adults With Metabolic Syndrome Components, Rashel L. Clark, Oluremi A. Famodu, Ida Holásková, Aniello M. Infante, Pamela J. Murray, I. Mark Olfert, Joseeph W. Mcfadden, Marianne T. Downes, Paul D. Chantler, Matthew W. Duespohl, Christopher F. Cuff, Melissa D. Olfert
Educational Intervention Improves Fruit And Vegetable Intake In Young Adults With Metabolic Syndrome Components, Rashel L. Clark, Oluremi A. Famodu, Ida Holásková, Aniello M. Infante, Pamela J. Murray, I. Mark Olfert, Joseeph W. Mcfadden, Marianne T. Downes, Paul D. Chantler, Matthew W. Duespohl, Christopher F. Cuff, Melissa D. Olfert
Faculty & Staff Scholarship
The FRUVEDomics study investigates the effect of a diet intervention focused on increasing fruit and vegetable intake on the gut microbiome and cardiovascular health of young adults with/at risk for metabolic syndrome(MetS). It was hypothesized that the recommended diet would result in metabolic and gut microbiome changes. The 9-week dietary intervention adhered to the US Department of Agriculture Dietary Guidelines for Americansand focused on increasing fruit and vegetable intake to equal half of the diet. Seventeen eligible young adults with/or at high risk of MetS consented and completed preintervention and postintervention measurements, including anthropometric, body composition, cardiovascular, …
Development Of The Icook 4-H Curriculum For Youth And Adults: Cooking, Eating, And Playing Together For Childhood Obesity Prevention, Lisa Franzen-Castle, Sarah E. Colby, Kendra K. Kattelmann, Melissa D. Olfert, Douglas R. Mathews, Kathryn Yerxa, Barbara Baker, Michelle Krehbiel, Tracey Lehrke, Kimberly Wilson, Sue M. Flanagan, Amber Ford, Trina Aguirre, Adrienne A. White
Development Of The Icook 4-H Curriculum For Youth And Adults: Cooking, Eating, And Playing Together For Childhood Obesity Prevention, Lisa Franzen-Castle, Sarah E. Colby, Kendra K. Kattelmann, Melissa D. Olfert, Douglas R. Mathews, Kathryn Yerxa, Barbara Baker, Michelle Krehbiel, Tracey Lehrke, Kimberly Wilson, Sue M. Flanagan, Amber Ford, Trina Aguirre, Adrienne A. White
Faculty & Staff Scholarship
The objective was to describe the development process of a curriculum (iCook 4-H) targeted to low-income, rural, and/or diverse youths and their adult primary meal preparer to promote cooking, eating, and playing together. Lessons learned highlighted the importance of grounding the curriculum in Social Cognitive Theory and applying the experiential 4-H learning model using a multiphased, community-based participatory approach with cyclical development and evaluation, and key modifications made for dissemination and distribution. Findings across 4 testing phases over 6 years and 5 states demonstrated the time-intensive, cyclical process that required flexibility with fidelity to form a hands-on, interactive …
The Icook 4-H Study: Report On Physical Activity And Sedentary Time In Youth Participating In A Multicomponent Program Promoting Family Cooking, Eating, And Playing Together, Kendra K. Kattelmann, Jessica R. Meendering, Emily J. Hofer, Chase M. Merfeld, Melissa D. Olfert, Rebeca L. Hagedorn, Sarah E. Colby, Lisa Franzen-Castle, Jonathan Moyer, Douglas R. Mathews, Adrienne A. White
The Icook 4-H Study: Report On Physical Activity And Sedentary Time In Youth Participating In A Multicomponent Program Promoting Family Cooking, Eating, And Playing Together, Kendra K. Kattelmann, Jessica R. Meendering, Emily J. Hofer, Chase M. Merfeld, Melissa D. Olfert, Rebeca L. Hagedorn, Sarah E. Colby, Lisa Franzen-Castle, Jonathan Moyer, Douglas R. Mathews, Adrienne A. White
Faculty & Staff Scholarship
Objective
To report physical activity and sedentary time outcomes of youth in iCook 4-H.
Study Design and Setting
iCook 4-Hwas a 5-state, randomized, control–treatment, family-based childhood obesity prevention intervention promoting cooking, eating, and playing together.
Participants and Intervention
Youth aged 9–10 years and the main preparer of their meals participated in the 12-week program followed by monthly newsletters and biyearly booster sessions until 24 months.
Main Outcome Measure(s)
A total of 155 youth were fitted with an Actigraph GT3X+ accelerometer, which they wore for 7 days at baseline and 4, 12, and 24 months to measure mean daily …
Dissemination Using Infographic Reports Depicting Program Impact Of A Community-Based Research Program: Eb4cast In Icook 4-H, Melissa D. Olfert, Rebecca L. Hagedorn, Makenzie L. Barr, Sarah E. Colby, Kendra K. Kattelmann, Lisa Franzen-Castle, Adrienne A. White
Dissemination Using Infographic Reports Depicting Program Impact Of A Community-Based Research Program: Eb4cast In Icook 4-H, Melissa D. Olfert, Rebecca L. Hagedorn, Makenzie L. Barr, Sarah E. Colby, Kendra K. Kattelmann, Lisa Franzen-Castle, Adrienne A. White
Faculty & Staff Scholarship
Objective
To evaluate barriers to dissemination and implementation and perceptions of the Evidence-Based Forecast Capture, Assemble, Sustain, Timelessness (eB4CAST) dissemination infographic tool as part of iCook 4-Hdissemination.
Design
Online surveys and phone interviews.
Participants
Experts (n = 35) in community research completed the survey; 13 completed the interview.
Main Outcomes Measure
Experts’ perceptions of eB4CAST reports used for iCook 4-Hdissemination.
Analysis
Frequency and thematic analysis.
Results
Survey respondents agreed (85%) that the eB4CAST infographic provided a clear understanding of iCook 4-Hand relevant information (83%). Statistics included in the infographic were reported as easily understood (66%). Respondents (83%) …
The Icook 4-H Study: An Intervention And Dissemination Test Of A Youth/Adult Out-Of-School Program, Adrienne A. White, Sarah E. Colby, Lisa Franzen-Castle, Kendra K. Kattelmann, Melissa D. Olfert, Tara A. Gould, Rebecca L. Hagedorn, Douglas R. Mathews, Jonathan Moyer, Kimberly Wilson, Kathryn Yerxa
The Icook 4-H Study: An Intervention And Dissemination Test Of A Youth/Adult Out-Of-School Program, Adrienne A. White, Sarah E. Colby, Lisa Franzen-Castle, Kendra K. Kattelmann, Melissa D. Olfert, Tara A. Gould, Rebecca L. Hagedorn, Douglas R. Mathews, Jonathan Moyer, Kimberly Wilson, Kathryn Yerxa
Faculty & Staff Scholarship
Objective
To describe outcomes from intervention and dissemination of iCook 4-H.
Design
Five-state, community-based participatory research and a randomized, controlled trial followed by a 5-state, nonrandomized dissemination test of the iCook 4-H curriculum with control and treatment groups.
Setting
Community and university sites.
Participants
Youths aged 9–10 years and their adult food preparer; 228 dyads in the intervention and 74 dyads in dissemination.
Intervention(s)
Theoretical frameworks were Social Cognitive Theory and the experiential 4-H learning model. Six 2-hour, biweekly sessions on cooking, eating, and playing together followed by monthly newsletters and boosters until 24 months, expanded to 8 sessions …
Development And Testing Of Program Evaluation Instruments For The Icook 4-H Curriculum, Douglas R. Mathews, Zachary J. Kunicki, Sarah E. Colby, Lisa Franzen-Castle, Kendra K. Kattelmann, Melissa D. Olfert, Adrienne A. White
Development And Testing Of Program Evaluation Instruments For The Icook 4-H Curriculum, Douglas R. Mathews, Zachary J. Kunicki, Sarah E. Colby, Lisa Franzen-Castle, Kendra K. Kattelmann, Melissa D. Olfert, Adrienne A. White
Faculty & Staff Scholarship
Objective
To develop and test the validity of program outcome evaluation instruments for cooking, eating, and playing together for obesity prevention during iCook 4-H.
Design
Instrument development for both youth and adults through pre-post testing of items newly constructed and compiled to address key curriculum constructs. Testing occurred throughout program intervention and dissemination to determine dimensionality, internal consistency and test-retest reliability, and validity.
Setting
A 5-state out-of-school program in cooperative extension and other community sites.
Participants
Youths aged 9–10 years; adults were main food preparers; the first phase involved 214 dyads and the second phase, 74 dyads.
Main Outcome …
Ripple Effect Mapping Outcomes Of A Childhood Obesity Prevention Program From Youth And Adult Dyads Using A Qualitative Approach: Icook 4-H, Melissa D. Olfert, Sina J. King, Rebecca L. Hagedorn, Makenzie L. Barr, Barbara A. Baker, Sarah E. Colby, Kendra K. Kattelmann, Lisa Franzen-Castle, Adrienne A. White
Ripple Effect Mapping Outcomes Of A Childhood Obesity Prevention Program From Youth And Adult Dyads Using A Qualitative Approach: Icook 4-H, Melissa D. Olfert, Sina J. King, Rebecca L. Hagedorn, Makenzie L. Barr, Barbara A. Baker, Sarah E. Colby, Kendra K. Kattelmann, Lisa Franzen-Castle, Adrienne A. White
Faculty & Staff Scholarship
Objective
To describe the impact of the iCook 4-H intervention study based on data gathered through ripple effect mapping focus groups through an explorative approach.Design
Youth–adult dyads responded about ways in which iCook had affected the individual, family, and community. Three questions were asked: (1) What were people doing differently as a result of iCook? (2) Who benefited from iCook and how? (3) Were there changes in the way community groups and institutions did things as a result of iCook?Setting
Ripple effect mapping sessions took place across 5 states (Maine, Nebraska, South Dakota, Tennessee, and West Virginia).Participants …
Enhancement Of Immune Response Against Bordetella Spp. By Disrupting Immunomodulation, Monica C. Gestal, Laura K. Howard, Kalyan Dewan, Hannah M. Johnson, Mariette Barbier, Clare Bryant, Illiassou Hamidou Soumana, Israel Rivera, Bodo Lina, Uriel Blas-Machado, Eric T. Harvill
Enhancement Of Immune Response Against Bordetella Spp. By Disrupting Immunomodulation, Monica C. Gestal, Laura K. Howard, Kalyan Dewan, Hannah M. Johnson, Mariette Barbier, Clare Bryant, Illiassou Hamidou Soumana, Israel Rivera, Bodo Lina, Uriel Blas-Machado, Eric T. Harvill
Faculty & Staff Scholarship
Well-adapted pathogens must evade clearance by the host immune system and the study of how they do this has revealed myriad complex strategies and mechanisms. Classical bordetellae are very closely related subspecies that are known to modulate adaptive immunity in a variety of ways, permitting them to either persist for life or repeatedly infect the same host. Exploring the hypothesis that exposure to immune cells would cause bordetellae to induce expression of important immunomodulatory mechanisms, we identified a putative regulator of an immunomodulatory pathway. The deletion of btrS in B. bronchiseptica did not affect colonization or initial growth in the …
Fourteen Polymorphic Microsatellite Markers For The Widespread Labrador Tea (Rhododendron Groenlandicum), Mathew L. Sheik, Kitty L. Labounty, Erika Mitchell, Emily L. Gillespie
Fourteen Polymorphic Microsatellite Markers For The Widespread Labrador Tea (Rhododendron Groenlandicum), Mathew L. Sheik, Kitty L. Labounty, Erika Mitchell, Emily L. Gillespie
Faculty & Staff Scholarship
PREMISE: Microsatellite markers were developed for Labrador tea (Rhododendron groenlandicum, Ericaceae) to facilitate downstream genetic investigation of this species and the extremely closely related, circumboreal Rhododendron subsect. Ledum. METHODS AND RESULTS: Forty-eight primer pairs were designed using Illumina data and screened for excellent amplification. Sixteen successful pairs were developed as microsatellite markers using fluorescently labeled amplification to generate chromatogram data. These data were evaluated for intrapopulation and interpopulation variability in three populations from Alaska and Maine, USA, and the Northwest Territories, Canada. Fourteen polymorphic markers genotyped reliably, each with one to eight alleles. Cluster analysis indicates that across the range, …
Systemic Inhibition Of Tissue-Nonspecific Alkaline Phosphatase Alters The Brain-Immune Axis In Experimental Sepsis, Allison L. Brichacek, Stanely A. Benkovic, Sreeparna Chakraborty, Divine C. Nwafor, Wei Wang, Sujung Jun, Duaa Dakhlallah, Werner Geldenhuys, Anthony B. Pinkerton, José Luis Millán, Candice M. Brown
Systemic Inhibition Of Tissue-Nonspecific Alkaline Phosphatase Alters The Brain-Immune Axis In Experimental Sepsis, Allison L. Brichacek, Stanely A. Benkovic, Sreeparna Chakraborty, Divine C. Nwafor, Wei Wang, Sujung Jun, Duaa Dakhlallah, Werner Geldenhuys, Anthony B. Pinkerton, José Luis Millán, Candice M. Brown
Faculty & Staff Scholarship
Tissue-nonspecific alkaline phosphatase (TNAP) is a ubiquitous enzyme present in many cells and tissues, including the central nervous system. Yet its functions at the brain-immune axis remain unclear. The goal of this study was to use a novel small molecular inhibitor of TNAP, SBI-425, to interrogate the function of TNAP in neuroimmune disorders. Following intraperitoneal (IP) administration of SBI-425, mass spectrometry analysis revealed that the SBI-425 does not cross the blood-brain barrier (BBB) in healthy mice. To elucidate the role of TNAP at the brain-immune axis, mice were subjected to experimental sepsis and received either vehicle or SBI-425 (25 mg/kg, …
Dna Methylation And Mirna-1296 Act In Concert To Mediate Spatiotemporal Expression Of Kpna7 During Bovine Oocyte And Early Embryonic Development, Lei Wang, Jacqelyn M. Hand, Liyuan Fu, George W. Smith, Jianbo Yao
Dna Methylation And Mirna-1296 Act In Concert To Mediate Spatiotemporal Expression Of Kpna7 During Bovine Oocyte And Early Embryonic Development, Lei Wang, Jacqelyn M. Hand, Liyuan Fu, George W. Smith, Jianbo Yao
Faculty & Staff Scholarship
Abstract
Background: Epigenetic regulation of oocyte-specific maternal factors is essential for oocyte and early embryonic development. KPNA7 is an oocyte-specific maternal factor, which controls transportation of nuclear proteins important for early embryonic development. To elucidate the epigenetic mechanisms involved in the controlled expression of KPNA7, both DNA methylation associated transcriptional silencing and microRNA (miRNA)-mediated mRNA degradation of KPNA7 were examined.
Results: Comparison of DNA methylation profiles at the proximal promoter of KPNA7 gene between oocyte and 6 different somatic tissues identified 3 oocyte-specific differentially methylated CpG sites. Expression of KPNA7 mRNA was reintroduced in bovine kidney-derived CCL2 cells after treatment …
Feasibility Of A Mhealth Approach To Nutrition Counseling In An Appalachian State, Melissa D. Olfert, Makenzie L. Barr, Rebecca L. Hagedorn, Dustin M. Long, Treah S. Haggerty, Mathew Weimer, Joseph Golden, Mary Ann Maurer, Jill D. Cochran, Tracy Hendershot, Stacey L. Whanger, Jay D. Mason, Sally L. Hodder
Feasibility Of A Mhealth Approach To Nutrition Counseling In An Appalachian State, Melissa D. Olfert, Makenzie L. Barr, Rebecca L. Hagedorn, Dustin M. Long, Treah S. Haggerty, Mathew Weimer, Joseph Golden, Mary Ann Maurer, Jill D. Cochran, Tracy Hendershot, Stacey L. Whanger, Jay D. Mason, Sally L. Hodder
Faculty & Staff Scholarship
Abstract: West Virginia is a rural state with an aging population that may experience barriers to accessing nutritional and lifestyle counseling. This study examined feasibility of an online personalized nutrition tracking application, Good Measures (GM), with patients at seven health care clinics throughout the state. Fourteen healthcare providers and 64 patients 18 years or older with a Body Mass Index (BMI) greater than or equal to 30 and access to the Internet were recruited for this 12-week feasibility study. Patient participants logged meals and exercise into the GM application via smart phone, tablet, or computer and virtually engaged with a …
The Influence Of Location On Water Quality Perceptions Across A Geographic And Socioeconomic Gradient In Appalachia, Ross G. Andrew, Robert C. Burns, Mary E. Allen
The Influence Of Location On Water Quality Perceptions Across A Geographic And Socioeconomic Gradient In Appalachia, Ross G. Andrew, Robert C. Burns, Mary E. Allen
Faculty & Staff Scholarship
Abstract: Understanding perceptions of water quality held by residents is critical to address gaps in public awareness and knowledge and may provide insight into what defines communities that are more/less resilient to changing water conditions locally. We sought to identify spatial patterns of water quality perceptions gathered in a survey of Southern West Virginia (WV) residents during spring/summer 2018. Using over 500 survey responses across 15 counties, we calculated spatial autocorrelation metrics and modeled the relationships between overall water quality perceptions and county-level socioeconomic endpoints, such as poverty rate, per capita income, and education level. We identified significant differences across …
A Case-Study Application Of The Experimental Watershed Study Design To Advance Adaptive Management Of Contemporary Watersheds, Jason A. Hubbart, Elliott Kellner, Sean J. Zeiger
A Case-Study Application Of The Experimental Watershed Study Design To Advance Adaptive Management Of Contemporary Watersheds, Jason A. Hubbart, Elliott Kellner, Sean J. Zeiger
Faculty & Staff Scholarship
settings Open AccessFeature PaperArticle
A Case-Study Application of the Experimental Watershed Study Design to Advance Adaptive Management of Contemporary Watersheds
by Jason A. Hubbart 1,*,Elliott Kellner 2 andSean J. Zeiger 3 1 West Virginia University, Institute of Water Security and Science, Davis College of Agriculture, Natural Resources and Design, Schools of Agriculture and Food, and Natural Resources, 3109 Agricultural Sciences Building, Morgantown, WV 26506, USA 2 West Virginia University, Institute of Water Security and Science, Davis College of Agriculture Natural Resources and Design, Division of Plant and Soil Sciences, 3011 Agricultural Sciences Building, Morgantown, WV 26506, USA 3 …
Increased Dementia Mortality In West Virginia Counties With Mountaintop Removal Mining?, A. K. Salm, Michael J. Benson
Increased Dementia Mortality In West Virginia Counties With Mountaintop Removal Mining?, A. K. Salm, Michael J. Benson
Faculty & Staff Scholarship
(MTM), a practice that has been ongoing in some counties of West Virginia (WV) USA since the 1970s. PM inhalation has been linked to central nervous system pathophysiology, including cognitive decline and dementia. Here we compared county dementia mortality statistics in MTM vs. non-MTM WV counties over a period spanning 2001–2015. We found significantly elevated age-adjusted vascular or unspecified dementia mortality/100,000 population in WV MTM counties where, after adjusting for socioeconomic variables, dementia mortality was 15.60 (±3.14 Standard Error of the Mean (S.E.M.)) times higher than that of non-MTM counties. Further analyses with satellite imaging data revealed a highly significant …
Finding New Cell Wall Regulatory Genes In Populus Trichocarpa Using Multiple Lines Of Evidence, Anna Furches, David Kainer, Deborah Weighill, Annabel Large, Piet Jones, Angelica M. Walker, Jonathon Romero, Joao Gabriel Felipe Machado Gazolla, Wayne Joubert, Manesh Shah, Jared Streich, Priya Ranjan, Jeremy Schmutz, Avinash Sreedasayam, David Macaya-Sanz, Nan Zhao, Madhavi Z. Martin, Xiaolan Rao, Richard A. Dixon, Stephen Difazio, Timothy J. Tschaplinski, Jin-Giu Chen, Gerald A. Tuskan, Daniel Jacobson
Finding New Cell Wall Regulatory Genes In Populus Trichocarpa Using Multiple Lines Of Evidence, Anna Furches, David Kainer, Deborah Weighill, Annabel Large, Piet Jones, Angelica M. Walker, Jonathon Romero, Joao Gabriel Felipe Machado Gazolla, Wayne Joubert, Manesh Shah, Jared Streich, Priya Ranjan, Jeremy Schmutz, Avinash Sreedasayam, David Macaya-Sanz, Nan Zhao, Madhavi Z. Martin, Xiaolan Rao, Richard A. Dixon, Stephen Difazio, Timothy J. Tschaplinski, Jin-Giu Chen, Gerald A. Tuskan, Daniel Jacobson
Faculty & Staff Scholarship
Understanding the regulatory network controlling cell wall biosynthesis is of great interest in Populus trichocarpa, both because of its status as a model woody perennial and its importance for lignocellulosic products. We searched for genes with putatively unknown roles in regulating cell wall biosynthesis using an extended network-based Lines of Evidence (LOE) pipeline to combine multiple omics data sets in P. trichocarpa, including gene coexpression, gene comethylation, population level pairwise SNP correlations, and two distinct SNP-metabolite Genome Wide Association Study (GWAS) layers. By incorporating validation, ranking, and filtering approaches we produced a list of nine high priority gene candidates for …
Prepontine Non-Giant Neurons Drive Flexible Escape Behavior In Zebrafish, Gregory D. Marquart, Kathryn M. Tabor, Sadie A. Bergeron, Kevin L. Briggman, Harold A. Burgess
Prepontine Non-Giant Neurons Drive Flexible Escape Behavior In Zebrafish, Gregory D. Marquart, Kathryn M. Tabor, Sadie A. Bergeron, Kevin L. Briggman, Harold A. Burgess
Faculty & Staff Scholarship
Many species execute ballistic escape reactions to avoid imminent danger. Despite fast reaction times, responses are often highly regulated, reflecting a trade-off between costly motor actions and perceived threat level. However, how sensory cues are integrated within premotor escape circuits remains poorly understood. Here, we show that in zebrafish, less precipitous threats elicit a delayed escape, characterized by flexible trajectories, which are driven by a cluster of 38 prepontine neurons that are completely separate from the fast escape pathway. Whereas neurons that initiate rapid escapes receive direct auditory input and drive motor neurons, input and output pathways for delayed escapes …
The “Motor Of The Day”: Parent And School-Age Children’S Cognitions, Barriers, And Supports For Breakfast, Kaitlyn M. Eck, Colleen L. Delaney, Rashel L. Clark, Miriam P. Leary, Karla Pagan Shelnutt, Melissa D. Olfert, Carol Byrd-Bredbenner
The “Motor Of The Day”: Parent And School-Age Children’S Cognitions, Barriers, And Supports For Breakfast, Kaitlyn M. Eck, Colleen L. Delaney, Rashel L. Clark, Miriam P. Leary, Karla Pagan Shelnutt, Melissa D. Olfert, Carol Byrd-Bredbenner
Faculty & Staff Scholarship
Despite the many benefits of regular breakfast consumption few parents and children consume this meal every day and research examining the determinants of breakfast consumption is limited. Thus, the purpose of this study was to examine breakfast-related cognitions (i.e., beliefs, attitudes, facilitators, barriers) of parents and school-age children (ages 6–11 years) using the constructs of Social Cognitive Theory as a guide. Parents (n = 37) and children (n = 41) participated in focus group discussions held in community settings in 3 states (FL, NJ, WV). Data were qualitatively content analyzed to detect trends. Parents felt breakfast was important for numerous …
Early Tree Growth In Reclaimed Mine Soils In Appalachia Usa, Kara Dallaire, Jefferey Skousen
Early Tree Growth In Reclaimed Mine Soils In Appalachia Usa, Kara Dallaire, Jefferey Skousen
Faculty & Staff Scholarship
Abstract: Surface mining disturbs hundreds of hectares of land every year in many areas of the world, thereby altering valuable, ecologically-diverse forests. Reforestation of these areas after mining helps to restore ecosystem functions and land value. In Appalachia, native topsoil is normally replaced on the surface during reclamation, but waivers allow for brown and gray sandstone materials to be used as topsoil substitutes. Numerous studies report the growth of trees in these substitute mine soil materials, but few studies have compared the height of trees grown in reclaimed mine soils to the heights of trees grown in native soils. This …
The Economics And Politics Of Carbon Taxes And Regulations: Evidence From Voting On Washington State’S Initiative 732, Michael Reed, Patrick O'Reilly, Joshua Hall
The Economics And Politics Of Carbon Taxes And Regulations: Evidence From Voting On Washington State’S Initiative 732, Michael Reed, Patrick O'Reilly, Joshua Hall
Faculty & Staff Scholarship
n November 2016, Washington State voters were presented with a ballot initiative (Initiative 732) advancing the first carbon tax on production and use of fossil fuels in the United States. Initiative 732 promised to reduce fossil fuel consumption by taxing carbon emissions, while remaining revenue-neutral by lowering taxes on businesses, consumers, and working families. In promising revenue-neutrality, Initiative 732 sought support beyond environmentalists and similarly sympathetic voters. It failed to pass, achieving 41.2 percent of votes cast. To investigate this initiative’s failure at the ballot, we analyzed zip code-level voting patterns and demographic data. Relying on a two-step LASSO (Least …
Time-Activity Budgets Of Stiff-Tailed Ducks In Puerto Rico, Nickolas S. Goodman, Jack C. Eitniear, James T. Anderson
Time-Activity Budgets Of Stiff-Tailed Ducks In Puerto Rico, Nickolas S. Goodman, Jack C. Eitniear, James T. Anderson
Faculty & Staff Scholarship
Habitat loss and degradation have contributed to declining populations of stiff-tailed ducks including the migratory northern ruddy duck (Oxyura jamaicensis rubida), and non-migratory masked duck (Nomonyx dominicus) and West Indian ruddy duck (Oxyura j. jamaicensis). Studies collecting time-activity budgets on waterfowl can provide important insight into habitat use, behavior, and niche partitioning. Even though the northern ruddy duck and West Indian ruddy duck are recognized as the same species, we treated them separately to appraise possible ecological differences. We recorded 24-h time-activity budgets for masked ducks (n = 142), northern ruddy ducks ( …
Nutritional Condition And Physiological Stress Levels Of Elk In The Black Hills, South Dakota, Chadwick P. Lehman, Christopher T. Rota, Joshua J. Millspaugh
Nutritional Condition And Physiological Stress Levels Of Elk In The Black Hills, South Dakota, Chadwick P. Lehman, Christopher T. Rota, Joshua J. Millspaugh
Faculty & Staff Scholarship
Percent of body fat and physiological stress are important correlates to wildlife demographics. We studied winter percent of body fat and physiological stress levels for a declining elk (Cervus canadensis nelsoni) population in South Dakota, 2011–2013. We obtained percent of winter body fat, pregnancy status, lactation status, and physiological stress data from 58 adult females (2+ years old). We compared physiological stress level data from 2011 with data collected from this same herd when elk densities were much higher (1995–1997). Our objectives were to determine percent of body fat during winter, examine if winter body fat was correlated with pregnancy …
Machine-Learning To Stratify Diabetic Patients Using Novel Cardiac Biomarkers And Integrative Genomics, Quincy A. Hathaway, Skyler M. Roth, Mark V. Pinti, Daniel C. Sprando, Amina Kunovac, Andrya J. Durr, Chris C. Cook, Garret K. Fink, Tristen B. Cheuvront, Jasmine H. Grossman, Ghadah A. Aljahli, Andrew D. Taylor, Andrew P. Giromini, Jessica L. Allen, John M. Hollander
Machine-Learning To Stratify Diabetic Patients Using Novel Cardiac Biomarkers And Integrative Genomics, Quincy A. Hathaway, Skyler M. Roth, Mark V. Pinti, Daniel C. Sprando, Amina Kunovac, Andrya J. Durr, Chris C. Cook, Garret K. Fink, Tristen B. Cheuvront, Jasmine H. Grossman, Ghadah A. Aljahli, Andrew D. Taylor, Andrew P. Giromini, Jessica L. Allen, John M. Hollander
Faculty & Staff Scholarship
Background: Diabetes mellitus is a chronic disease that impacts an increasing percentage of people each year. Among its comorbidities, diabetics are two to four times more likely to develop cardiovascular diseases. While HbA1c remains the primary diagnostic for diabetics, its ability to predict long-term, health outcomes across diverse demographics, ethnic groups, and at a personalized level are limited. The purpose of this study was to provide a model for precision medicine through the implementation of machine-learning algorithms using multiple cardiac biomarkers as a means for predicting diabetes mellitus development. Methods: Right atrial appendages from 50 patients, 30 non-diabetic and 20 …
Integrated Pest Management Of Longan (Sapindales: Sapindaceae) In Vietnam, Hanh Tran, Hoa Nguyen Van, Rangaswamy Muniappan, James Amrine, Rayapati Naidu, Robert Cilbertson, Jaspreet Sidhu
Integrated Pest Management Of Longan (Sapindales: Sapindaceae) In Vietnam, Hanh Tran, Hoa Nguyen Van, Rangaswamy Muniappan, James Amrine, Rayapati Naidu, Robert Cilbertson, Jaspreet Sidhu
Faculty & Staff Scholarship
This paper describes the current state of pests and diseases of longan (Dimocarpus longan Lour.) and their management in Vietnam. Longan is the third most cultivated fruit crop and second major fruit crop exported from Vietnam. Brief descriptions of arthropod pests Eriophyes dimocarpi Kuang (Acari: Eriophyidae), Conogethes punctiferalis Guenée (Lepidoptera: Crambidae), Conopomorpha sinensis Bradley (Lepidoptera: Gracillariidae), Conopomorpha litchiella Bradley (Lepidoptera: Gracillariidae), Tessaratoma papillosa Drury (Hemiptera: Tessaratomidae), Eudocima phalonia L. comb. (Lepidoptera: Erebidae), oriental fruit fly Bactrocera dorsalis Hendel (Diptera: Tephretidae), Planococcus lilacinus Cockerell (Hemiptera: Pseudococcidae), Drepanococcus chiton Green (Hemiptera: Coccidae), and Cornegenapsylla sinica Yang & Li (Hemiptera: Psyllidae) and fungal …