Life Sciences Commons^™

The Maine Chance: Private-Public Partnership And The Katahdin Woods And Waters National Monument, Char Miller

Pomona Faculty Publications and Research

The claim of a federal “land grab” in response to the creation of Katahdin Woods and Waters National Monument in Maine revealed a lack of historical awareness by critics of how two other cherished parks were established there: through private-public partnerships and the donation of land by private citizens.

Paul Faulstich’S Reflective Review Of Susan A. Phillips’ Essay, Paul Faulstich

Pitzer Faculty Publications and Research

Paul Faulstich's review of Susan A. Phillips' essay titled, "Huerta del Valle: A New Nonprofit in a Neglected Landscape".

A Revision Of The Octocoral Genus Ovabunda Alderslade, 2001 (Anthozoa, Octocorallia, Xeniidae), Catherine S. Mcfadden, Yehuda Benayahu, Anna Halász, Dafna Aharonovich, Robert Toonen

All HMC Faculty Publications and Research

The family Xeniidae (Octocorallia) constitutes an abundant benthic component on many Indo-West Pacific coral reefs and is ecologically important in the Red Sea. The genus Ovabunda Alderslade, 2001 was recently established to accommodate previous Xenia species with sclerites comprised of a mass of minute corpuscle-shaped microscleres. The aim of the present study was to examine type material of Xenia species in order to verify their generic affiliation. We present here a comprehensive account of the genus Ovabunda, using scanning electron microscopy to depict sclerite microstructure. We assign three Xenia species to the genus: O. ainex comb. n., O. …

A New Species Of Ovabunda (Octocorallia, Xeniidae) From The Andaman Sea, Thailand With Notes On The Biogeography Of This Genus, Catherine S. Mcfadden, Michael P. Janes, Thanongsak Chanmethakul

All HMC Faculty Publications and Research

A survey of xeniid octocorals was carried out in the waters off Southwestern Thailand in September, 2007. Microscopic investigation of the colonies revealed that three specimens belonged to the genus Ovabunda. Gross morphological examination is presented here accompanied by scanning electron micrographs of the sclerites. Molecular phylogenetic analysis showed identical genotypes at mtMutS, COI, and 28S rDNA for all three specimens and supports their generic assignment. Colony size and shape, sclerite size, and pinnule arrangement differ from nominal species of Ovabunda and thus a new species, O. andamanensis is introduced here. This work also presents a new …

Uncle Sam’S Badge: Identity And Representation In The Usda Forest Service, 1905–2013, Char Miller

Pomona Faculty Publications and Research

Howard Abbey could recall the exact moment when he learned that he had passed the forest ranger’s examination for the newly established USDA Forest Service (USFS). In the early morning of Aug. 1, 1905, while he was managing a team of horses pulling a mowing machine on the McIntosh Ranch in the northern Sierra Nevada Mountains, Allen Ray Powers, a Forest Assistant on the Plumas Forest Reserve, rode up and “informed me that I was wanted at the Forest Supervisor’s office in Quincy.” Abbey handed over the reins to his boss and walked the 2 miles to town where he …

Social Aggregation In Pea Aphids: Experiment And Random Walk Modeling, Christa Nilsen, John Paige, Olivia Warner, Benjamin Mayhew, Ryan Sutley, Matthew Lam '15, Andrew J. Bernoff, Chad M. Topaz

All HMC Faculty Publications and Research

From bird flocks to fish schools and ungulate herds to insect swarms, social biological aggregations are found across the natural world. An ongoing challenge in the mathematical modeling of aggregations is to strengthen the connection between models and biological data by quantifying the rules that individuals follow. We model aggregation of the pea aphid, Acyrthosiphon pisum. Specifically, we conduct experiments to track the motion of aphids walking in a featureless circular arena in order to deduce individual-level rules. We observe that each aphid transitions stochastically between a moving and a stationary state. Moving aphids follow a correlated random walk. …

Sinularia Leptoclados (Ehrenberg, 1834) (Cnidaria: Octocorallia) Re-Examined, Catherine S. Mcfadden, Leen P. Van Ofwegen, Yehuda Benayahu

All HMC Faculty Publications and Research

Sinularia leptoclados (Ehrenberg, 1834) is re-described. Sinularia leptoclados var. gonatodes Kolonko, 1926 is synonymized with S. maxima Verseveldt, 1977. Two new species of Sinularia with digitiform lobules, leptoclados-type surface clubs and unbranched interior spindles, are described. An updated maximum likelihood tree of Sinularia species with leptoclados-type clubs (clade 5C) based on two mitochondrial genes (mtMutS, COI) and a nuclear gene (28S rDNA) is presented.

Molecular Phylogenetic Evidence Supports A New Family Of Octocorals And A New Genus Of Alcyoniidae (Octocorallia: Alcyonacea), Catherine S. Mcfadden, Leen P. Van Ofwegen

All HMC Faculty Publications and Research

Molecular phylogenetic evidence indicates that the octocoral family Alcyoniidae is highly polyphyletic, with genera distributed across Octocorallia in more than 10 separate clades. Most alcyoniid taxa belong to the large and poorly resolved Holaxonia–Alcyoniina clade of octocorals, but members of at least four genera of Alcyoniidae fall outside of that group. As a first step towards revision of the family, we describe a new genus, Parasphaerasclera gen. n., and family, Parasphaerascleridae fam. n., of Alcyonacea to accommodate species of Eleutherobia Pütter, 1900 and Alcyonium Linnaeus, 1758 that have digitiform to digitate or lobate growth forms, completely lack sclerites …

Serum 25-Hydroxyvitamin D Levels And C-Reactive Protein In Persons With Human Immunodeficiency Virus Infection, C. Anderson Johnson, Kalpana Poudel-Tandukar, Krishna C. Poudel, Masamine Jimba, Jun Kobayashi, Paula Palmer

CGU Faculty Publications and Research

Human immunodeficiency virus (HIV) infection has frequently been associated with vitamin D deficiency as well as chronic inflammatory response. We tested the hypothesis of an independent relationship between serum concentrations of 25-hydroxyvitamin D [25(OH)D] and high-sensitivity C-reactive protein (CRP) in a cohort of HIV-positive people. A cross-sectional survey was conducted among 316 HIV-positive people (181 men and 135 women) aged 16 to 60 years residing in the Kathmandu Valley, Nepal. Serum high-sensitivity CRP concentrations and serum 25(OH)D levels were measured by the latex agglutination nephelometry method and the competitive protein-binding assay, respectively. The relationship between serum CRP concentrations and 25(OH)D …

Making Common Cause For Conservation: The Pinchot Institute And Grey Towers National Historic Site, 1963-2013, Char Miller

Pomona Faculty Publications and Research

This year marks the 50th anniversary of the establishment of the Pinchot Institute for Conservation and the donation of the Pinchot family home Grey Towers to the U.S. Forest Service. In the following essay, historian and Pinchot biographer Char Miller discusses how the Institute is applying Gifford Pinchot’s principles to contemporary environmental issues. It is adapted from Seeking the Greatest Good: The Conservation Legacy of Gifford Pinchot, his new history of the Institute, and is published with kind permission of the University of Pittsburgh Press.

Trace Element Soil Contamination At Urban Community Gardens In Washington, Dc, Adam J. Long

Environmental Analysis Program Mellon Student Summer Research Reports

In recent years, urban gardening has become a popular form of environmental, food, and social justice. Urban community gardens such as those in Washington, DC can reduce the environmental footprint of food production, provide access to healthy produce in “food deserts,” and provide other social, educational, and even financial benefits. However, the rising popularity of urban gardening has put many people in close contact with urban soils, which are likely to contain various contaminants due to concentrated human activity over extended periods of time. This study investigates heavy metal soil contaminants found in community gardens located in Washington, DC. 45 …

Post-Speleogenetic Biogenic Modification Of Gomantong Caves, Sabah, Borneo, Joyce Lundberg, Donald A. Mcfarlane

WM Keck Science Faculty Papers

The Gomantong cave system of eastern Sabah, Malaysia, is well-known as an important site for harvesting edible bird-nests and, more recently, as a tourist attraction. Although the biology of the Gomantong system has been repeatedly studied, very little attention has been given to the geomorphology. Here, we report on the impact of geobiological modification in the development of the modern aspect of the cave, an important but little recognized feature of tropical caves. Basic modeling of the metabolic outputs from bats and birds (CO₂, H₂O, heat) reveals that post-speleogenetic biogenic corrosion can erode bedrock by between …

Deep-Sea Origin And In-Situ Diversification Of Chrysogorgiid Octocorals, Catherine S. Mcfadden, Eric Pante, Scott C. France, Arnaud Couloux, Corinne Cruaud, Sarah Samadi, Les Watling

All HMC Faculty Publications and Research

The diversity, ubiquity and prevalence in deep waters of the octocoral family Chrysogorgiidae Verrill, 1883 make it noteworthy as a model system to study radiation and diversification in the deep sea. Here we provide the first comprehensive phylogenetic analysis of the Chrysogorgiidae, and compare phylogeny and depth distribution. Phylogenetic relationships among 10 of 14 currently-described Chrysogorgiidae genera were inferred based on mitochondrial (mtMutS, cox1) and nuclear (18S) markers. Bathymetric distribution was estimated from multiple sources, including museum records, a literature review, and our own sampling records (985 stations, 2345 specimens). Genetic analyses suggest that the Chrysogorgiidae as currently described is …

How Muscles Function - The Work Loop Technique, Anna N. Ahn

All HMC Faculty Publications and Research

Anna Ahn discusses Bob Josephson’s 1985 paper entitled: ‘Mechanical power output from striated muscle during cyclic contraction’.

Escherichia Coli Lacking Rpos Are Rare In Natural Populations Of Non-Pathogens, Emily Snyder '11, David M. Gordon, Daniel M. Stoebel

All HMC Faculty Publications and Research

The alternative sigma factor RpoS controls a large regulon that allows E. coli to respond to a variety of stresses. Mutations in rpoS can increase rates of nutrient acquisition at the cost of a decrease in stress resistance. These kinds of mutations evolve rapidly under certain laboratory conditions where nutrient acquisition is especially challenging. The frequency of strains lacking RpoS in natural populations of E. coli is less clear. Such strains have been found at frequencies over 20% in some collections of wild isolates. However, laboratory handling can select for RpoS-null strains and may have affected some of these strain …

Evolution Of Spur-Length Diversity In Aquilegia Petals Is Achieved Solely Through Cell-Shape Anisotropy, Joshua R. Puzey, Sharon J. Gerbode, Scott A. Hodges, Elena M. Kramer, L. Mahadevan

All HMC Faculty Publications and Research

The role of petal spurs and specialized pollinator interactions has been studied since Darwin. Aquilegia petal spurs exhibit striking size and shape diversity, correlated with specialized pollinators ranging from bees to hawkmoths in a textbook example of adaptive radiation. Despite the evolutionary significance of spur length, remarkably little is known about Aquilegia spur morphogenesis and its evolution. Using experimental measurements, both at tissue and cellular levels, combined with numerical modelling, we have investigated the relative roles of cell divisions and cell shape in determining the morphology of the Aquilegia petal spur. Contrary to decades-old hypotheses implicating a discrete meristematic zone …

Subaerial Freshwater Stromatolites In Deer Cave, Sarawak – A Unique Geobiological Cave Formation, Joyce Lundberg, Donald A. Mcfarlane

WM Keck Science Faculty Papers

A suite of distinctive freshwater subaerial phosphatic stromatolites is developed close to the northeastern entrance of Deer Cave, Gunung Mulu National Park, Sarawak, Borneo, in conditions of very low light but ample supply of nutrients from guano. These stromatolites are not particulate; they are composed of alternating layers of more porous and more dense amorphous hydroxylapatite. This biomineralization occurs as moulds of coccoid (the majority) and filamentous (less abundant) cyanobacteria. Mineralization occurs at a pH of ~ 7.0 in the extracellular sheaths and in micro-domains of varying carbonate content in the surrounding mucus of the biofilm. The most recent surfaces …

Effect Of Substrate Composition And Alignment On Corneal Cell Phenotype, Donna Phu '09, Lindsay S. Wray '08, Robert V. Warren '10, Richard C. Haskell, Elizabeth J. Orwin

All HMC Faculty Publications and Research

Corneal blindness is a significant problem treated primarily by corneal transplants. Donor tissue supply is low, creating a growing need for an alternative. A tissue-engineered cornea made from patient-derived cells and biopolymer scaffold materials would be widely accessible to all patients and would alleviate the need for donor sources. Previous work in this lab led to a method for electrospinning type I collagen scaffolds for culturing corneal fibroblasts ex vivo that mimics the microenvironment in the native cornea. This electrospun scaffold is composed of small-diameter, aligned collagen fibers. In this study, we investigate the effect of scaffold nanostructure and composition …

A New Genus Of Soft Coral Of The Family Alcyoniidae (Cnidaria, Octocorallia) With Re-Description Of A New Combination And Description Of A New Species, Catherine S. Mcfadden, Yehuda Benayahu

All HMC Faculty Publications and Research

A new genus, Aldersladum (family Alcyoniidae), is established to accommodate a previously described species, Effl atounaria sodwanae Benayahu, 1993 (family Xeniidae) from Sodwana Bay, South Africa that was wrongly assigned to the latter genus. Th is species is redescribed and a second new species, A. jengi from Penghu Is., Taiwan, is described. Th e diagnostic features of the new genus include the presence of only figure-eight shaped platelets in all parts of the colony, thus differentiating it from all known genera of the Alcyoniidae. Based on examination of additional material from other localities, the zoogeographical distribution of the genus is …

Do Longer Delays Matter? The Effect Of Prolonging Delay In Ctl Activation, Angela Gallegos, Ami E. Radunskaya

Pomona Faculty Publications and Research

The activation of a specific immune response takes place in the lymphoid organs such as the spleen. We present here a simplified model of the proliferation of specific immune cells in the form of a single delay equation. We show that the system can undergo switches in stability as the delay is increased, and we interpret these results in the context of sustaining an effective immune response to a dendritic cell vaccine.

Inter-Colony Comparison Of Diving Behavior Of An Arctic Top Predator: Implications For Warming In The Greenland Sea, Nina J. Karnovsky, Zachary W. Brown '07, Jorg Welcker, Ann M.A. Harding, Wojciech Walkusz, André Cavalcanti, Johanna S. Hardin, Alexander Kitaysky, Geir Gabrielsen, David Grémillet

Pomona Faculty Publications and Research

The goal of this study was to assess how diverse oceanographic conditions and prey communities affect the foraging behavior of little auks Alle alle. The Greenland Sea is characterized by 3 distinct water masses: (1) the East Greenland Current (EGC), which carries Arctic waters southward; (2) the Sørkapp Current (SC), which originates in the Arctic Ocean but flows north along the west coast of Spitsbergen; and (3) the West Spitsbergen Current (WSC), which carries warm Atlantic-derived water north. Each of these 3 water masses is characterized by a distinct mesozooplankton community. Little auks breeding adjacent to the EGC have …

"Toward Integration: From Quantitative Biology To Mathbio-Biomath?", Pat Marsteller, Lisette G. De Pillis, Ann Findley, Karl Joplin, John Pelesko, Karen Nelson, Katerina Thompson, David Usher, Joseph Watkins

All HMC Faculty Publications and Research

In response to the call of BIO2010 for integrating quantitative skills into undergraduate biology education, 30 Howard Hughes Medical Institute (HHMI) Program Directors at the 2006 HHMI Program Directors Meeting established a consortium to investigate, implement, develop, and disseminate best practices resulting from the integration of math and biology. With the assistance of an HHMI-funded mini-grant, led by Karl Joplin of East Tennessee State University, and support in institutional HHMI grants at Emory and University of Delaware, these institutions held a series of summer institutes and workshops to document progress toward and address the challenges of implementing a more quantitative …

Neural Reuse As A Source Of Developmental Homology, David S. Moore, Chris Moore

Pitzer Faculty Publications and Research

Neural reuse theories should interest developmental psychologists because these theories can potentially illuminate the developmental relations among psychological characteristics observed across the lifespan. Characteristics that develop by exploiting pre-existing neural circuits can be thought of as developmental homologues. And, understood in this way, the homology concept that has proven valuable for evolutionary biologists can be used productively to study psychological/behavioral development.

Kinematic Evidence For Superfast Locomotory Muscle In Two Species Of Teneriffiid Mites, Grace C. Wu, Jonathan C. Wright, Dwight L. Whitaker, Anna N. Ahn

All HMC Faculty Publications and Research

Locomotory muscles typically operate over a narrow range of contraction frequencies, characterized by the predominant fiber types and functional roles. The highest documented frequencies in the synchronous sound-producing muscles of insects (550 Hz) and toadfish (200 Hz) far exceed the contraction frequencies observed in weight-bearing locomotory muscles, which have maximum documented frequencies below 15-30 Hz. Laws of scaling, however, predict that smaller arthropods may employ stride frequencies exceeding this range. In this study we measured running speed and stride frequency in two undescribed species of teneriffiid mites from the coastal sage scrub of southern California. Relative speeds of both species …

An Extraordinary Example Of Photokarren In A Sandstone Cave, Cueva Charles Brewer, Chimantá Plateau, Venezuela: Biogeomorphology On A Small Scale, Joyce Lundberg, Donald A. Mcfarlane, Charles Brewer-Carias

WM Keck Science Faculty Papers

A distinctive suite of small-scale erosional forms that are oriented towards the light occur close to the entrance of Cueva Charles Brewer, a large cave in a sandstone tepui, in SE Venezuela. These are the third example of photokarren ever studied in the world, the other two being from Borneo and Ireland. They are the only photokarren ever described from sandstone, and the only example from a non-carbonate environment. The host rock is a poorly-lithified unit of the Precambrian quartz arenite of the Roraima Supergroup. The forms are all oriented towards the light at 30° regardless of rock surface orientation. …

A Unique Population Of Cave Bears (Carnivora: Ursidae) From The Middle Pleistocene Of Kents Cavern, England, Based On Dental Morphometrics, Donald A. Mcfarlane, Martin Sabol, Joyce Lundberg

WM Keck Science Faculty Papers

The ‘breccia’ stratum from Kents (we follow local tradition in using the form ‘Kents’, without an apostrophe) Cavern, England, has been well known for its rich yield of cave-bear material since excavations began in the mid-19th century. Recent work has established that the bears are of latest MIS 12 or earliest MIS 11 age. A life table based on a collection of 67 molariform teeth is consistent with the use of the cave as a hibernaculum. Univariate and morphological assessment of the teeth shows an unusual range of primitive and more derived characters. Multivariate morphometric analysis of cave-bear teeth from …

Jane: A New Tool For The Cophylogeny Reconstruction Problem, Chris Conow, Daniel Fielder '11, Yaniv J. Ovadia '10, Ran Libeskind-Hadas

All HMC Faculty Publications and Research

Background

This paper describes the theory and implementation of a new software tool, called Jane, for the study of historical associations. This problem arises in parasitology (associations of hosts and parasites), molecular systematics (associations of orderings and genes), and biogeography (associations of regions and orderings). The underlying problem is that of reconciling pairs of trees subject to biologically plausible events and costs associated with these events. Existing software tools for this problem have strengths and limitations, and the new Jane tool described here provides functionality that complements existing tools.

Results

The Jane software tool uses a polynomial time dynamic …

Sex, Mixability, And Modularity, Adi Livnat, Christos Papadimitriou, Nicholas Pippenger, Marcus W. Feldman

All HMC Faculty Publications and Research

The assumption that different genetic elements can make separate contributions to the same quantitative trait was originally made in order to reconcile biometry and Mendelism and ever since has been used in population genetics, specifically for the trait of fitness. Here we show that sex is responsible for the existence of separate genetic effects on fitness and, more generally, for the existence of a hierarchy of genetic evolutionary modules. Using the tools developed in the process, we also demonstrate that in terms of their fitness effects, separation and fusion of genes are associated with the increase and decrease of the …

Figs, Wasps, Gophers, And Lice: A Computational Exploration Of Coevolution, Ran Libeskind-Hadas

All HMC Faculty Publications and Research

This chapter explores the topic of coevolution: the genetic change in one species in response to the change in another. For example, in some cases, a parasite species might evolve to specialize with its host species. In other cases, the relationship between two species may be mutually beneficial and coevolution may serve to strengthen the benefits of that relationship.

Mathematical Biology At An Undergraduate Liberal Arts College, Stephen C. Adolph, Lisette G. De Pillis

All HMC Faculty Publications and Research

Since 2002 we have offered an undergraduate major in Mathematical Biology at Harvey Mudd College. The major was developed and is administered jointly by the mathematics and biology faculty. In this paper we describe the major, courses, and faculty and student research and discuss some of the challenges and opportunities we have experienced.