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Full-Text Articles in Life Sciences

Messy Eating, Samantha King, R Scott Carey, Isabel Macquarie, Victoria Millious, Elaine Power Jun 2019

Messy Eating, Samantha King, R Scott Carey, Isabel Macquarie, Victoria Millious, Elaine Power

Environmental Studies

Literature on the ethics and politics of food and that on animal-human relationships have infrequently converged. Representing an initial step towards bridging this divide, Messy Eating features interviews with thirteen prominent and emerging scholars about the connections between their academic work and their approach to consuming animals as food. The collection explores how authors working across a range of perspectives—postcolonial, Indigenous, Black, queer, trans, feminist, disability, poststructuralist, posthumanist, and multispecies—weave their theoretical and political orientations with daily, intimate, and visceral practices of food consumption, preparation, and ingestion.

Contributors: Neel Ahuja, Billy Ray Belcourt, Matthew Calarco, Lauren Corman, Naisargi ...


Reoccupy Earth [Table Of Contents], David Wood Apr 2019

Reoccupy Earth [Table Of Contents], David Wood

Philosophy

Habit rules our lives. And yet climate change and the catastrophic future it portends, makes it clear that we cannot go on like this.

Our habits are integral to narratives of the good life, to social norms and expectations, as well as to economic reality. Such shared shapes are vital. Yet while many of our individual habits seem perfectly reasonable, when aggregated together they spell disaster. Beyond consumerism, other forms of life and patterns of dwelling are clearly possible. But how can we get there from here?

Philosophy is about emancipation—from illusions, myths, and oppression. In Reoccupy Earth, the ...


Study Guides And Videos For Openstax Biology, Chapters 5-7 (Egsc), Martiana Sega, David Chevalier Apr 2019

Study Guides And Videos For Openstax Biology, Chapters 5-7 (Egsc), Martiana Sega, David Chevalier

Biological Sciences Ancillary Materials

This set of videos and study guides for OpenStax Biology was created under an ALG Mini-Grant for Ancillary Materials Creation and Revision. Two videos on energy coupling and osmosis are include, along with study guides for chapters 5-8:

  • Plasma Membrane
  • Metabolism
  • Cellular Respiration

All files are included in one .zip folder.


Exterranean [Table Of Contents], Phillip John Usher Mar 2019

Exterranean [Table Of Contents], Phillip John Usher

Literature

“For anyone who might be suffering from Anthropocene fatigue, this is a book to jolt you from your slumbers. What happens to the globe when we shift attention from the outward projection of emissions to extraction ? The Earth we thought we knew, and were already mourning, takes on a stunning new critical light.”—Claire Colebrook, Pennsylvania State University

Exterranean concerns the extraction of stuff from the Earth, a process in which matter goes from being sub- to exterranean. By bringing a rich archive of nonmodern texts and images from across Europe, into conversation with the contemporary work of Bruno Latour ...


Farmer Attitudes Toward Cooperative Approaches To Herbicide Resistance Management: A Common Pool Ecosystem Service Challenge, David E. Ervin, Elise H. Breshears, George B. Frisvold, Terrance M. Hurley, Katherine E. Dentzman, Jeffrey L. Gunsolus, Raymond A. Jussaume, Micheal D. K. Owen, Jason Norsworthy, Mustofa Mahmud Al Mamun, Wesley Everman Mar 2019

Farmer Attitudes Toward Cooperative Approaches To Herbicide Resistance Management: A Common Pool Ecosystem Service Challenge, David E. Ervin, Elise H. Breshears, George B. Frisvold, Terrance M. Hurley, Katherine E. Dentzman, Jeffrey L. Gunsolus, Raymond A. Jussaume, Micheal D. K. Owen, Jason Norsworthy, Mustofa Mahmud Al Mamun, Wesley Everman

Environmental Science and Management Faculty Publications and Presentations

Dramatic growth in herbicide-resistant (HR) weeds in the United States threatens farm profitability and may undercut environmentally beneficial farming practices. When HR weeds move across farm boundaries due to ecological processes or human action, a common pool resource challenge emerges, requiring farmer cooperation to manage such weeds effectively. We investigate the scope for cooperative management using responses to a national survey on HR weed issues to test a recursive model of three preconditions for collective action: (1) concern about HR weeds migrating from nearby lands; (2) communication with neighbors about HR weeds; and (3) belief that cooperation is necessary for ...


Estimating Relative Abundance Of Young-Of-The-Year American Eel, Anguilla Rostrata, In The Virginia Tributaries Of Chesapeake Bay, Spring 2018, Troy D. Tuckey, Mary C. Fabrizio Mar 2019

Estimating Relative Abundance Of Young-Of-The-Year American Eel, Anguilla Rostrata, In The Virginia Tributaries Of Chesapeake Bay, Spring 2018, Troy D. Tuckey, Mary C. Fabrizio

Reports

American Eel (Anguilla rostrata) is a valuable commercial species along the Atlantic coast of North America from New Brunswick to Florida. In the U.S., harvests have declined, with similar patterns occurring in the Canadian Maritime Provinces (Meister and Flagg 1997). An average of 62% of the annual landings of U.S. commercial harvest since 1993 have come from the Chesapeake Bay (personal communication from the National Marine Fisheries Service, Fisheries Statistics Division, 9 February 2015). In 2013, Virginia commercial landings were approximately 100,298 lbs; since mandatory reporting began in 1993, average annual landings in Virginia have been 193 ...


Stability Analysis Of Kernel Quality Traits In Exotic-Derived Doubled Haploid Maize Lines, Adam Vanous, Candice Gardner, Michael Blanco, Adam Martin-Schwarze, Jinyu Wang, Xianran Li, Alexander E. Lipka, Sherry Flint-Garcia, Martin Bohn, Jode Edwards, Thomas Lubberstedt Mar 2019

Stability Analysis Of Kernel Quality Traits In Exotic-Derived Doubled Haploid Maize Lines, Adam Vanous, Candice Gardner, Michael Blanco, Adam Martin-Schwarze, Jinyu Wang, Xianran Li, Alexander E. Lipka, Sherry Flint-Garcia, Martin Bohn, Jode Edwards, Thomas Lubberstedt

Agronomy Publications

Variation in kernel composition across maize (Zea mays L.) germplasm is affected by a combination of the plant’s genotype, the environment in which it is grown, and the interaction between these two elements. Adapting exotic germplasm to the US Corn Belt is highly dependent on the plant’s genotype, the environment where it is grown, and the interaction between these components. Phenotypic plasticity is ill-defined when specific exotic germplasm is moved over large latitudinal distances and for the adapted variants being created. Reduced plasticity (or stability) is desired for the adapted variants, as it allows for a more rapid ...


Effects Of An Unregistered Insecticide On Adult Spotted Wing Drosophila Mortality And Field Infestation Rates, 2015, Katharine A. Swoboda-Bhattarai, Hannah Burrack Feb 2019

Effects Of An Unregistered Insecticide On Adult Spotted Wing Drosophila Mortality And Field Infestation Rates, 2015, Katharine A. Swoboda-Bhattarai, Hannah Burrack

Faculty Publications: Department of Entomology

The effectiveness of an unregistered material at reducing Drosophila suzukii (SWD) infestation rates in blackberry field plots and its toxicity to adult SWD in laboratory bioassays was tested during the 2015 growing season. Field trials were conducted at the Sandhills Research Station near Jackson Springs, NC, in a 0.11-acre planting consisting of two rows of ‘Ouachita’ blackberries. Six treatments, including an untreated check (UTC), were applied to 5-plant plots and were arranged in an RCB design with four replicates per treatment, blocked by row, with two blocks per row. Delegate was the standard material. Some of the treatments were ...


Predation On Stink Bugs (Hemiptera: Pentatomidae) In Cotton And Soybean Agroecosystems [Predator Gut Contents], Kacie J. Athey, John R. Ruberson, Dawn Olson, James D. Harwood Feb 2019

Predation On Stink Bugs (Hemiptera: Pentatomidae) In Cotton And Soybean Agroecosystems [Predator Gut Contents], Kacie J. Athey, John R. Ruberson, Dawn Olson, James D. Harwood

Entomology Research Data

Stink bugs (Hemiptera: Pentatomidae) are significant pests of cotton and soybeans in the southeastern United States with annual control costs exceeding $14 million in these crops. Three of the most prominent stink bug pests are the southern green (Nezara viridula), brown (Euschistus servus) and green (Chinavia hilaris) stink bugs. To determine trophic linkages between generalist arthropod predators and these pests, species-specific 16S molecular markers were designed and used to detect the presence of prey DNA in predator gut-contents. Over 2700 predators were collected over two growing seasons in cotton and soybean in southern Georgia in 2011 and 2012 and screened ...


Predation On Stink Bugs (Hemiptera: Pentatomidae) In Cotton And Soybean Agroecosystems [Predator Capture Numbers], Kacie J. Athey, John R. Ruberson, Dawn Olson, James D. Harwood Feb 2019

Predation On Stink Bugs (Hemiptera: Pentatomidae) In Cotton And Soybean Agroecosystems [Predator Capture Numbers], Kacie J. Athey, John R. Ruberson, Dawn Olson, James D. Harwood

Entomology Research Data

Stink bugs (Hemiptera: Pentatomidae) are significant pests of cotton and soybeans in the southeastern United States with annual control costs exceeding $14 million in these crops. Three of the most prominent stink bug pests are the southern green (Nezara viridula), brown (Euschistus servus) and green (Chinavia hilaris) stink bugs. To determine trophic linkages between generalist arthropod predators and these pests, species-specific 16S molecular markers were designed and used to detect the presence of prey DNA in predator gut-contents. Over 2700 predators were collected over two growing seasons in cotton and soybean in southern Georgia in 2011 and 2012 and screened ...


Update On The Human And Mouse Lipocalin (Lcn) Gene Family, Including Evidence The Mouse Mup Cluster Is Result Of An "Evolutionary Bloom"., Georgia Charkoftaki, Yewei Wang, Monica Mcandrews, Elspeth A Bruford, David C Thompson, Vasilis Vasiliou, Daniel W Nebert Feb 2019

Update On The Human And Mouse Lipocalin (Lcn) Gene Family, Including Evidence The Mouse Mup Cluster Is Result Of An "Evolutionary Bloom"., Georgia Charkoftaki, Yewei Wang, Monica Mcandrews, Elspeth A Bruford, David C Thompson, Vasilis Vasiliou, Daniel W Nebert

Faculty Research 2019

Lipocalins (LCNs) are members of a family of evolutionarily conserved genes present in all kingdoms of life. There are 19 LCN-like genes in the human genome, and 45 Lcn-like genes in the mouse genome, which include 22 major urinary protein (Mup) genes. The Mup genes, plus 29 of 30 Mup-ps pseudogenes, are all located together on chromosome (Chr) 4; evidence points to an "evolutionary bloom" that resulted in this Mup cluster in mouse, syntenic to the human Chr 9q32 locus at which a single MUPP pseudogene is located. LCNs play important roles in physiological processes by binding and transporting small ...


Using Publicly Available Genbank Data To Teach Plant Phylogeny In High School Classrooms, Madhav P. Nepal, Ethan J. Andersen Feb 2019

Using Publicly Available Genbank Data To Teach Plant Phylogeny In High School Classrooms, Madhav P. Nepal, Ethan J. Andersen

iLEARN Teaching Resources

In this teaching module, students will learn about NCBI GenBank, search for DNA/protein sequences from multiple plant species of a gene that encodes Rubisco enzyme, construct and interpret a phylogenetic tree, and discuss traits that allowed plants to adapt their life on land.


The Legacy Of Natural Species And Substantial Form For Thomistic Evolution, James R. Hofmann Feb 2019

The Legacy Of Natural Species And Substantial Form For Thomistic Evolution, James R. Hofmann

Forum Lectures

Exploration of theistic evolution within a Thomistic framework has taken on the label of Thomistic evolution. Although the conceptual boundaries of this approach are not precise, a historical trajectory of its scholastic methodology can be traced back to the views of Aquinas himself. An enduring central concept in this tradition has been the idea of substantial form. For Aquinas, distinct substantial forms were associated with the kinds of animals and plants that have no prior ancestry and are ascribed to God's production during the Genesis days of adornment. Later in the tradition, the early twentieth century Jesuit Erich Wasmann ...


Evaluating Motivational Interviewing And Habit Formation To Enhance The Effect Of Activity Trackers On Healthy Adults’ Activity Levels: Randomized Intervention, Laura D. Ellingson, Jeni E. Lansing, Kathryn J. Deshaw, Karissa L. Peyer, Yang Bai, Maria Perez, L. Alison Phillips, Gregory Welk Feb 2019

Evaluating Motivational Interviewing And Habit Formation To Enhance The Effect Of Activity Trackers On Healthy Adults’ Activity Levels: Randomized Intervention, Laura D. Ellingson, Jeni E. Lansing, Kathryn J. Deshaw, Karissa L. Peyer, Yang Bai, Maria Perez, L. Alison Phillips, Gregory Welk

Psychology Publications

Background: While widely used and endorsed, there is limited evidence supporting the benefits of activity trackers for increasing physical activity; these devices may be more effective when combined with additional strategies that promote sustained behavior change like motivational interviewing (MI) and habit development. Objective: This study aims to determine the utility of wearable activity trackers alone or in combination with these behavior change strategies for promoting improvements in active and sedentary behaviors. Methods: A sample of 91 adults (48/91 female, 53%) was randomized to receive a Fitbit Charge alone or in combination with MI and habit education for 12 ...


Mrub_3018 Is Orthologous To E. Coli B2759 (Casb), Kyle Parker, Dr. Lori Scott Feb 2019

Mrub_3018 Is Orthologous To E. Coli B2759 (Casb), Kyle Parker, Dr. Lori Scott

Meiothermus ruber Genome Analysis Project

This project is part of the Meiothermus ruber genome analysis project, which uses a collection of online bioinformatics tools to predict gene function. We studied the biological activity of the Mrub_3018 gene, which we hypothesize is orthologous to E. coli gene B2759. We predicted that Mrub_3018(DNA coordinates 3057916… 3058524) encodes the protein CasB. CasB is a protein in the CRISPR CASCADE that will function as a structural protein. When the rest of the proteins form an “S” formation CasB will connect the front and back of the “S” creating a back bone for the structure. It will help bind ...


Mrub_3019 Casa Gene Is An Ortholog To E. Coli B2760, Kelsey Heiland, Dr. Lori Scott Feb 2019

Mrub_3019 Casa Gene Is An Ortholog To E. Coli B2760, Kelsey Heiland, Dr. Lori Scott

Meiothermus ruber Genome Analysis Project

This research is part of the Meiothermus ruber genome annotation project which aims to predict gene function with various bioinformatics tools. We investigated the function of Mrub_3019, which encodes the CasA protein involved in the multi-subunit effector complex for the CRISPR-Cas immunity system and predicted it to be an ortholog of E. coli K12 MG1655 b2760 (casA). We predicted that Mrub_3019 encodes the protein CasA, which is involved in PAM recognition of CRISPR interference pathway. Foreign DNA will bind to CasA, which signals Cas3 for helicase-mediated DNA degradation. Our hypothesis is supported by low E-values for pairwise alignment in NCBI ...


Mrub_3015 Is Orthologous To The B2757 Gene Found In Escherichia Coli Coding For Casd, Ramona Collins, Dr. Lori Scott Feb 2019

Mrub_3015 Is Orthologous To The B2757 Gene Found In Escherichia Coli Coding For Casd, Ramona Collins, Dr. Lori Scott

Meiothermus ruber Genome Analysis Project

This project is part of the Meiothermus ruber genome analysis project, which uses a collection of online bioinformatics tools to predict gene function. We investigated the biological function of the gene Mrub_3015, which we hypothesize is a component of the CRISPR-Cas prokaryotic defense system. We predict that Mrub_3015 (DNA coordinates 3055550...3056245) encodes the the CRISPR-associated protein cas5, which is integral in maintaining the crRNA-DNA structure, keeping the complex from base pairing with the target phage DNA. Our hypothesis is supported by identical hits for Mrub_3015 and b2527 to the KEGG, Pfam, TIGRfam, CDD and PDB databases as well as ...


The Ethics Of Human-Animal Relationships And Public Discourse: A Case Study Of Lions Bred For Their Bones, Peter Coals, Dawn Burnham, Andrew Loveridge, David W. Macdonald, Michael 'T Sas-Rolfes, Vivvienne Williams, John A. Vucetich Feb 2019

The Ethics Of Human-Animal Relationships And Public Discourse: A Case Study Of Lions Bred For Their Bones, Peter Coals, Dawn Burnham, Andrew Loveridge, David W. Macdonald, Michael 'T Sas-Rolfes, Vivvienne Williams, John A. Vucetich

School of Forest Resources and Environmental Science Publications

Conservation and natural resource management are increasingly attending the ethical elements of public decisions. Ethical considerations are challenging, in part, because they typically require accounting for the moral consideration of various human and nonhuman forms of life, whose interests sometimes conflict (or seem to conflict). A valuable tool for such evaluations is the formal analysis of ethical arguments. An ethical argument is a collection of premises, logically interrelated, to yield a conclusion that can be expressed in the form, “We ought to…” According to the rules of logic, a conclusion is supported by an argument if all its premises are ...


Adaptation Strategies And Approaches For Forested Watersheds, P. Danielle Shannon, Christopher Swanston, Maria Janowiak, Stephen D. Handler, Kristen M. Schmitt, Leslie A. Brandt, Patricia Butler-Leopold Feb 2019

Adaptation Strategies And Approaches For Forested Watersheds, P. Danielle Shannon, Christopher Swanston, Maria Janowiak, Stephen D. Handler, Kristen M. Schmitt, Leslie A. Brandt, Patricia Butler-Leopold

School of Forest Resources and Environmental Science Publications

Intentional climate adaptation planning for ecosystems has become a necessary part of the job for natural resource managers and natural resource professionals in this era of non-stationarity. One of the major challenges in adapting ecosystems to climate change is in the translation of broad adaptation concepts to specific, tangible actions. Addressing management goals and values while considering the long-term risks associated with local climate change can make forested watershed management plans more robust to uncertainty and changing conditions. We provide a menu of tiered adaptation strategies, which we developed with a focus on forests of the Midwest and Northeastern U ...


Wildfire Activity And Land Use Drove 20th‐Century Changes In Forest Cover In The Colorado Front Range, Kyle Rodman, Thomas T. Veblen, Sara Saraceni, Teresa B. Chapman Feb 2019

Wildfire Activity And Land Use Drove 20th‐Century Changes In Forest Cover In The Colorado Front Range, Kyle Rodman, Thomas T. Veblen, Sara Saraceni, Teresa B. Chapman

Geography Graduate Contributions

Recent shifts in global forest area highlight the importance of understanding the causes and consequences of forest change. To examine the influence of several potential drivers of forest cover change, we used supervised classifications of historical (1938–1940) and contemporary (2015) aerial imagery covering a 2932‐km2study area in the northern Front Range (NFR) of Colorado and we linked observed changes in forest cover with abiotic factors, land use, and fire history. Forest cover in the NFR demonstrated broad‐scale changes 1938–2015 and overall cover increased 7.8%, but there was notable spatial variability and many sites also experienced ...


Analyzing Drug Release Kinetics From Water-Soluble Polymers, Sean M. Kelly, Arun K. Upadhyay, Akash Mitra, Balaji Narasimhan Feb 2019

Analyzing Drug Release Kinetics From Water-Soluble Polymers, Sean M. Kelly, Arun K. Upadhyay, Akash Mitra, Balaji Narasimhan

Chemical and Biological Engineering Publications

The ability to develop predictive mathematical models of therapeutic release from pharmaceutical formulations has enormous potential to enhance our understanding of such systems and improve the controlled release of the payload. The current work describes the development and testing of a one-dimensional model of drug transport from amorphous, swelling/dissolving polymers. Model parameters such as the diffusivities of water and drug, the initial loading of the drug, the polymer dissolution rate, drug-polymer interactions, and the tablet thickness were varied, demonstrating the ability to tune the release to be controlled by either drug diffusion or polymer chain disentanglement. In addition, predictions ...


Sex And Limb Impact Biomechanics Associated With Risk Of Injury During Drop Landing With Body Borne Load, Kayla D. Seymore, Auralea C. Fain, Nicholas J. Lobb, Tyler N. Brown Feb 2019

Sex And Limb Impact Biomechanics Associated With Risk Of Injury During Drop Landing With Body Borne Load, Kayla D. Seymore, Auralea C. Fain, Nicholas J. Lobb, Tyler N. Brown

Kinesiology Faculty Publications and Presentations

Increasing lower limb flexion may reduce risk of musculoskeletal injury for military personnel during landing. This study compared lower limb biomechanics between sexes and limbs when using normal and greater lower limb flexion to land with body borne load. Thirty-three participants (21 male, 12 female, age: 21.6±2.5 years, height: 1.7±0.1 m, weight: 74.5±9.0 kg) performed normal and flexed lower limb landings with four body borne loads: 20, 25, 30 and 35 kg. Hip and knee biomechanics, peak vertical ground reaction force (GRF), and the magnitude and direction of the GRF vector ...


Interacting Stressors Matter: Diet Quality And Virus Infection In Honeybee Health, Adam G. Dolezal, Jimena Carrillo-Tripp, Timothy M. Judd, W. Allen Miller, Bryony C. Bonning, Amy L. Toth Feb 2019

Interacting Stressors Matter: Diet Quality And Virus Infection In Honeybee Health, Adam G. Dolezal, Jimena Carrillo-Tripp, Timothy M. Judd, W. Allen Miller, Bryony C. Bonning, Amy L. Toth

Ecology, Evolution and Organismal Biology Publications

Honeybee population declines have been linked to multiple stressors, including reduced diet diversity and increased exposure to understudied viral pathogens. Despite interest in these factors, few experimental studies have explored the interaction between diet diversity and viral infection in honeybees. Here, we used a mixture of laboratory cage and small semi-field nucleus hive experiments to determine how these factors interact. In laboratory experiments, we found that high-quality diets (polyfloral pollen and high-quality single-source pollen) have the potential to reduce mortality in the face of infection with Israeli acute paralysis virus (IAPV). There was a significant interaction between diet and virus ...


Comparison Of Microbial Communities In The Sediments And Water Columns Of Frozen Cryoconite Holes In The Mcmurdo Dry Valleys, Antarctica, Pacifica Sommers, John Lawrence Darcy, Dorota L. Porazinska, Eli M.S. Gendron, Andrew G. Fountain, Felix Zamora, Kim Vincent, Kaelin M. Cawley, Adam J. Solon, Lara Vimercati, Jenna Ryder, Steven K. Schmidt Feb 2019

Comparison Of Microbial Communities In The Sediments And Water Columns Of Frozen Cryoconite Holes In The Mcmurdo Dry Valleys, Antarctica, Pacifica Sommers, John Lawrence Darcy, Dorota L. Porazinska, Eli M.S. Gendron, Andrew G. Fountain, Felix Zamora, Kim Vincent, Kaelin M. Cawley, Adam J. Solon, Lara Vimercati, Jenna Ryder, Steven K. Schmidt

University Libraries Open Access Fund Supported Publications

Although cryoconite holes, sediment-filled melt holes on glacier surfaces, appear small and homogenous, their microbial inhabitants may be spatially partitioned. This partitioning could be particularly important for maintaining biodiversity in holes that remain isolated for many years, such as in Antarctica. We hypothesized that cryoconite holes with greater species richness and biomass should exhibit greater partitioning between the sediments and water, promoting greater biodiversity through spatial niche partitioning. We tested this hypothesis by sampling frozen cryoconite holes along a gradient of biomass and biodiversity in the Taylor Valley, Antarctica, where ice-lidded cryoconite holes are a ubiquitous feature of glaciers. We ...


Heterodera Glycines Utilizes Promiscuous Spliced Leaders And Demonstrates A Unique Preference For A Species-Specifc Spliced Leader Over C. Elegans Sl1, Stacey N. Barnes, Rick E. Masonbrink, Tom R. Maier, Arun S. Seetharam, Anoop S. Sindhu, Andrew J. Severin, Thomas J. Baum Feb 2019

Heterodera Glycines Utilizes Promiscuous Spliced Leaders And Demonstrates A Unique Preference For A Species-Specifc Spliced Leader Over C. Elegans Sl1, Stacey N. Barnes, Rick E. Masonbrink, Tom R. Maier, Arun S. Seetharam, Anoop S. Sindhu, Andrew J. Severin, Thomas J. Baum

Office of Biotechnology Publications

Spliced leader trans-splicing (SLTS) plays a part in the maturation of pre-mRNAs in select species across multiple phyla but is particularly prevalent in Nematoda. The role of spliced leaders (SL) within the cell is unclear and an accurate assessment of SL occurrence within an organism is possible only after extensive sequencing data are available, which is not currently the case for many nematode species. SL discovery is further complicated by an absence of SL sequences from high-throughput sequencing results due to incomplete sequencing of the 5'-ends of transcripts during RNA-seq library preparation, known as 5'-bias. Existing datasets and ...


Towards Large Scale Automated Cage Monitoring - Diurnal Rhythm And Impact Of Interventions On In-Cage Activity Of C57bl/6j Mice Recorded 24/7 With A Non-Disrupting Capacitive-Based Technique., Karin Pernold, F Iannello, Benjamin E. Low, M Rigamonti, G Rosati, F Scavizzi, J Wang, M Raspa, Michael V. Wiles, B Ulfhake Feb 2019

Towards Large Scale Automated Cage Monitoring - Diurnal Rhythm And Impact Of Interventions On In-Cage Activity Of C57bl/6j Mice Recorded 24/7 With A Non-Disrupting Capacitive-Based Technique., Karin Pernold, F Iannello, Benjamin E. Low, M Rigamonti, G Rosati, F Scavizzi, J Wang, M Raspa, Michael V. Wiles, B Ulfhake

Faculty Research 2019

BACKGROUND AND AIMS: Automated recording of laboratory animal's home cage behavior is receiving increasing attention since such non-intruding surveillance will aid in the unbiased understanding of animal cage behavior potentially improving animal experimental reproducibility.

MATERIAL AND METHODS: Here we investigate activity of group held female C57BL/6J mice (mus musculus) housed in standard Individually Ventilated Cages across three test-sites: Consiglio Nazionale delle Ricerche (CNR, Rome, Italy), The Jackson Laboratory (JAX, Bar Harbor, USA) and Karolinska Insititutet (KI, Stockholm, Sweden). Additionally, comparison of female and male C57BL/6J mice was done at KI. Activity was recorded using a capacitive-based sensor ...


Fishing Technologies: Specification And Estimation, Quinn Weninger, Larry Perruso, Helle Bunzel Feb 2019

Fishing Technologies: Specification And Estimation, Quinn Weninger, Larry Perruso, Helle Bunzel

Economics Working Papers

This paper consistently estimates the structural properties of a multiple-species fishing technology. Our approach overcomes two ubiquitous features of fisheries data generating processes that invalidate classical estimators: (1) unobservability, by the researcher, of the in situ fish stock, and (2) endogenous production decisions that vary with fishermen’s private information about stock abundance and other economic vari- ables. Our estimations obtain consistency by exploiting the timing of production de- cisions and the information available to fishermen when endogenous production scale and scope, i.e., targeting of individual species’, decisions are made. Our estimator adopts methods used in fisheries stock assessment ...


Question Answering For Suicide Risk Assessment Using Reddit, Amanuel Alambo, Usha Lokala, Ugur Kursuncu, Krishnaprasad Thirunarayan, Amelia Gyrard, Randon S. Welton, Jyotishman Pathak, Amit P. Sheth Feb 2019

Question Answering For Suicide Risk Assessment Using Reddit, Amanuel Alambo, Usha Lokala, Ugur Kursuncu, Krishnaprasad Thirunarayan, Amelia Gyrard, Randon S. Welton, Jyotishman Pathak, Amit P. Sheth

Kno.e.sis Publications

Mental Health America designed ten questionnaires that are used to determine the risk of mental disorders. They are also commonly used by Mental Health Professionals (MHPs) to assess suicidality. Specifically, the Columbia Suicide Severity Rating Scale (C-SSRS), a widely used suicide assessment questionnaire, helps MHPs determine the severity of suicide risk and offer an appropriate treatment. A major challenge in suicide treatment is the social stigma wherein the patient feels reluctance in discussing his/her conditions with an MHP, which leads to inaccurate assessment and treatment of patients. On the other hand, the same patient is comfortable freely discussing his ...


Enhancing The Efficacy Of Glycolytic Blockade In Cancer Cells Via Rad51 Inhibition., John J Wilson, Kin-Hoe Chow, Nathan J Labrie, Jane Branca, Thomas J. Sproule, Bryant R A Perkins, Elise E Wolf, Mauro W Costa, Grace Stafford, Christine Rosales, Kevin D Mills, Derry C. Roopenian, Muneer G. Hasham Feb 2019

Enhancing The Efficacy Of Glycolytic Blockade In Cancer Cells Via Rad51 Inhibition., John J Wilson, Kin-Hoe Chow, Nathan J Labrie, Jane Branca, Thomas J. Sproule, Bryant R A Perkins, Elise E Wolf, Mauro W Costa, Grace Stafford, Christine Rosales, Kevin D Mills, Derry C. Roopenian, Muneer G. Hasham

Faculty Research 2019

Targeting the early steps of the glycolysis pathway in cancers is a well-established therapeutic strategy; however, the doses required to elicit a therapeutic effect on the cancer can be toxic to the patient. Consequently, numerous preclinical and clinical studies have combined glycolytic blockade with other therapies. However, most of these other therapies do not specifically target cancer cells, and thus adversely affect normal tissue. Here we first show that a diverse number of cancer models - spontaneous, patient-derived xenografted tumor samples, and xenografted human cancer cells - can be efficiently targeted by 2-deoxy-D-Glucose (2DG), a well-known glycolytic inhibitor. Next, we tested the ...


The Global State Of The Genetic Counseling Profession., Maryann Abacan, Lamia Alsubaie, Kristine Barlow-Stewart, Beppy Caanen, Christophe Cordier, Eliza Courtney, Emeline Davoine, Janice Edwards, Niby J Elackatt, Kate Gardiner, Yue Guan, Lian-Hua Huang, Charlotta Ingvoldstad Malmgren, Sahil Kejriwal, Hyon J Kim, Deborah Lambert, Paulina Araceli Lantigua-Cruz, Juliana M H Lee, Marianne Lodahl, Åshild Lunde, Shelley Macaulay, Ivan Macciocca, Sonia Margarit, Anna Middleton, Ramona Moldovan, Joanne Ngeow, Alexandra J Obregon-Tito, Kelly E Ormond, Milena Paneque, Karen Powell, Kunal Sanghavi, Diana Scotcher, Jenna Scott, Clara Serra Juhé, Shiri Shkedi-Rafid, Tina-Marié Wessels, Sook-Yee Yoon, Catherine Wicklund Feb 2019

The Global State Of The Genetic Counseling Profession., Maryann Abacan, Lamia Alsubaie, Kristine Barlow-Stewart, Beppy Caanen, Christophe Cordier, Eliza Courtney, Emeline Davoine, Janice Edwards, Niby J Elackatt, Kate Gardiner, Yue Guan, Lian-Hua Huang, Charlotta Ingvoldstad Malmgren, Sahil Kejriwal, Hyon J Kim, Deborah Lambert, Paulina Araceli Lantigua-Cruz, Juliana M H Lee, Marianne Lodahl, Åshild Lunde, Shelley Macaulay, Ivan Macciocca, Sonia Margarit, Anna Middleton, Ramona Moldovan, Joanne Ngeow, Alexandra J Obregon-Tito, Kelly E Ormond, Milena Paneque, Karen Powell, Kunal Sanghavi, Diana Scotcher, Jenna Scott, Clara Serra Juhé, Shiri Shkedi-Rafid, Tina-Marié Wessels, Sook-Yee Yoon, Catherine Wicklund

Faculty Research 2019

The profession of genetic counseling (also called genetic counselling in many countries) began nearly 50 years ago in the United States, and has grown internationally in the past 30 years. While there have been many papers describing the profession of genetic counseling in individual countries or regions, data remains incomplete and has been published in diverse journals with limited access. As a result of the 2016 Transnational Alliance of Genetic Counseling (TAGC) conference in Barcelona, Spain, and the 2017 World Congress of Genetic Counselling in the UK, we endeavor to describe as fully as possible the global state of genetic ...