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Musculoskeletal Injury Concealment In The Reserve Officers’ Training Corps, Joshua D. Wooldridge May 2023

Musculoskeletal Injury Concealment In The Reserve Officers’ Training Corps, Joshua D. Wooldridge

UNLV Theses, Dissertations, Professional Papers, and Capstones

INTRODUCTION: Among service members, musculoskeletal injuries threaten military readiness and place a substantial burden on medical and financial resources. While musculoskeletal injuries (MSKIs) are a leading threat to military readiness, service members’ unwillingness to seek care constrains current prevention and surveillance efforts. A growing body of evidence shows US service members conceal a large proportion of injuries, especially in training environments. The Reserve Officers’ Training Corps is a critical training environment for future US military commissioned officers. Reserve Officers’ Training Corps (ROTC) is the largest commissioning source of new officers for the US military. ROTC cadets are college students concurrently …


Dimensionality Of Natural Auditory Scene Perception: A Factor Analysis Study, Margaret A. Mcmullin Dec 2022

Dimensionality Of Natural Auditory Scene Perception: A Factor Analysis Study, Margaret A. Mcmullin

UNLV Theses, Dissertations, Professional Papers, and Capstones

Theories of auditory and visual scene analysis suggest the perception of scenes relies on the identification and segregation of objects within it, resembling a detail-oriented processing style, but it is possible that a global-oriented process also occurs while evaluating auditory scenes. There is evidence for global properties that enable rapid recognition of visual scenes, even without recognizing the individual objects comprising the scene. It is our understanding that a similar line of research has not been explored in the auditory domain; therefore, we evaluated the contributions of high-level global and low-level acoustic information to auditory scene perception. A secondary aim …


Hunter-Gatherers In Context: Hadzabe People And Early Nutrition Transition, Trevor Pollom Dec 2022

Hunter-Gatherers In Context: Hadzabe People And Early Nutrition Transition, Trevor Pollom

UNLV Theses, Dissertations, Professional Papers, and Capstones

The current study utilizes a mixed-methods approach to investigate the processes that influence landcover change and nutrition transitions in the Lake Eyasi Basin area of Northern Tanzania. In doing so, it provides unique insights into the behavior and biology of Hadzabe foragers living in the Yaeda Valley during the early stages of nutrition transition and provides much needed context for scientific literature that has been derived from this region. The current study answers the following questions: 1) How can historical and ethnographic maps, combined with present-day landcover classifications, inform our understanding of the people(s), spaces, and places of Lake Eyasi? …


Cognitive Testing For Sport Concussion: The Immediate Post-Concussion Assessment And Cognitive Testing (Impact), Julia E. Maietta Aug 2022

Cognitive Testing For Sport Concussion: The Immediate Post-Concussion Assessment And Cognitive Testing (Impact), Julia E. Maietta

UNLV Theses, Dissertations, Professional Papers, and Capstones

Sport concussion is among the most common injuries for an athlete to experience during sport participation. Because of the complex pathophysiological process that affects the brain during and after concussion, symptoms can be heterogeneous in presence and severity. Although most acute symptoms (e.g., headache, slowed processing speed, loss of consciousness, irritability, depression, anxiety) resolve within seven to 10 days for most athletes, there is evidence that higher initial symptom burden and other genetically based differences can lead to longer symptom duration and complicated recovery post-concussion. Because structural changes that commonly occur as a result of concussion (e.g., diffuse axonal injury) …


Attentional Focus And The Development Of Skilled Performance, Harjiv Singh May 2022

Attentional Focus And The Development Of Skilled Performance, Harjiv Singh

UNLV Theses, Dissertations, Professional Papers, and Capstones

A central question in the development of skilled movement is: how a performer should focus their attention while preparing for the execution of a motor skill? Considerable evidence has shown that directing attention towards an intended movement effect (i.e., external focus) results in performance benefits relative to focusing on body movements (i.e., internal focus). While most of the previous research has emphasized the effects of internal versus external foci, evidence also suggests that external foci located at greater distances from the body (distal foci) are more effective than external foci located in greater proximity to the body (proximal foci) and …


The Effects Of Executive Function Between Anxiety And Math Achievement In Adolescents, Mckenzie Hall May 2022

The Effects Of Executive Function Between Anxiety And Math Achievement In Adolescents, Mckenzie Hall

UNLV Theses, Dissertations, Professional Papers, and Capstones

Anxiety in Children can develop into pervasive disorders in adulthood if not treated. Research shows dysfunctional Executive Function (EF) and anxiety are both shown to have a negative impact on math achievement in children and adolescents (Trezise & Reeve, 2018; Kalaycioglu, 2015; Owens, Stevenson, Hadwin & Norgate, 2012). Chung, Weyandt, and Swentosky (2014) found biological and neuropsychological support for EF as a unitary and multifaceted processor for regulating our emotional states as well as our daily procedures. Anderson’s (2002) model of Executive Control System (ECS) allows the factors of EF to be examined using a developmental approach towards EF processes. …


Multiple Approaches To Auditory Rhythm: Development Of Sustained Musical Beat And The Relation To Language, Development Of Rhythmic Categories Via Iterated Production, And A Meta-Analytic Study Of Neural Entrainment To Beat, Karli Marie Nave Dec 2021

Multiple Approaches To Auditory Rhythm: Development Of Sustained Musical Beat And The Relation To Language, Development Of Rhythmic Categories Via Iterated Production, And A Meta-Analytic Study Of Neural Entrainment To Beat, Karli Marie Nave

UNLV Theses, Dissertations, Professional Papers, and Capstones

Rhythm is ubiquitous to human communication, coordination, and experience of music. In this dissertation, I address three empirical questions through three different methodologies, all of which contribute to the growing body of literature on human auditory rhythm processing. In Chapter 2, I present a registered report detailing the results of independent conceptual replications of Nozaradan, Peretz, Missal, & Mouraux (2011), all using the same vetted protocol. Listeners performed the same tasks as in Nozaradan et al. (2011), with the addition of behavioral measures of perception. In neuroscience, neural correlates to musical beat perception have been identified, yet little to no …


Estimation Of Spatial Change In Cropland Area And Evaluation Of Irrigation Performance In Imperial Valley Using Remotely Sensed Data, Usha Poudel May 2021

Estimation Of Spatial Change In Cropland Area And Evaluation Of Irrigation Performance In Imperial Valley Using Remotely Sensed Data, Usha Poudel

UNLV Theses, Dissertations, Professional Papers, and Capstones

The Imperial Valley (IV) in the US is an extensively irrigated agricultural region, which includes multiple crops changing on an annual and semiannual basis. The valley is facing grave concerns about water management due to its semi-arid environment, water intensive crops, and limited water supply. A simple, inexpensive, and repeatable method to detect changes in cropping patterns may assist irrigation managers to understand crop diversification and associated consumptive use. In addition, a spatial assessment of existing water irrigation system performance and productivity is crucial to benchmark and improve current water management strategies. This thesis estimates the spatial pattern of change …


Investigation Of Algorithms To Assess Validity Of Wearable Technology During Field Testing, Brenna Barrios May 2021

Investigation Of Algorithms To Assess Validity Of Wearable Technology During Field Testing, Brenna Barrios

UNLV Theses, Dissertations, Professional Papers, and Capstones

Wearable technology is an emerging fitness trend where the technology which supports it lacks validity verification. Furthermore, heart rate validity of these devices vary greatly when observed in laboratory settings vs. field testing. Secondarily, Consumer Technology Association guidelines require a minimum five minute trial for wearable testing. This study examined heart rate data of previously tested wearable devices (Garmin Fenix 5, Jabra Elite Sport, Motiv Ring, Scosche Rhythm+) in an outdoor setting to further understand their performance, and to examine the relationship of the five minute regulation. Two separate algorithms were applied to the original data set, the first shortened …


Discovering Motor Phenotypes In Autism Spectrum Disorder: A Cross-Syndrome Approach, Daniel Edwin Lidstone Dec 2019

Discovering Motor Phenotypes In Autism Spectrum Disorder: A Cross-Syndrome Approach, Daniel Edwin Lidstone

UNLV Theses, Dissertations, Professional Papers, and Capstones

Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder with a behavioral phenotype characterized by persistent deficits in social communication and social interaction accompanied by restricted, repetitive patterns of behaviors, interests, or activities. Currently in the US, approximately 2.5% of children have a diagnosis of ASD. The etiology of ASD is complex, however the disorder does have a strong genetic basis. Specific genetic mutations can lead to neuroanatomical and neurophysiological changes during development resulting in a behavioral phenotype that falls along the ASD spectrum and may result in a diagnosis of ASD. The severity of ASD-specific behaviors falls on a continuum …


Multi-Polygenic Risk Score Prediction Model For Bipolar Disorder, Travis Mize Aug 2019

Multi-Polygenic Risk Score Prediction Model For Bipolar Disorder, Travis Mize

UNLV Theses, Dissertations, Professional Papers, and Capstones

Bipolar disorder (BP), a severe mental disorder characterized by recurring manic and depressive episodes, has been shown to have a strong genetic underpinning. Current theory suggests that it is the summation of risk alleles, spread across the entirety of the genome, which contributes to the development of BP, as well as other polygenic traits. The comorbid nature of these polygenic traits are often problematic for diagnosticians as the symptomology of the disorders may vary substantially between individuals and can create diagnostic confusion. To alleviate issues such as these, a more objective measure, to be used alongside current diagnostic procedures, is …


Optimization Of Motor Performance, Lee-Kuen Chua Aug 2019

Optimization Of Motor Performance, Lee-Kuen Chua

UNLV Theses, Dissertations, Professional Papers, and Capstones

According to the OPTIMAL (Optimizing Performance Through Intrinsic Motivation and Attention of Learning) theory of motor learning, enhanced expectancies (EE), autonomy support (AS), and external focus (EF) augment the coupling of a person’s actions to intended movement goals. This goal-action coupling is postulated to boost a person’s focus on goal-related aspects of the motor task while reducing the person’s self-related thoughts, resulting in enhanced performance of skilled movements as well as in improving the acquisition outcomes for the learning of motor skills. The three studies in this compilation report were aimed at providing empirical evidence for the motor performance benefits …


Analysis Of Spheno-Occipital Synchondrosis (Sos) Fusion In A Contemporary Southern Nevada Subadult Hispanic Population Using Archival Cone-Beam Computerized Tomography (Cbct) Images, Megan Baker May 2019

Analysis Of Spheno-Occipital Synchondrosis (Sos) Fusion In A Contemporary Southern Nevada Subadult Hispanic Population Using Archival Cone-Beam Computerized Tomography (Cbct) Images, Megan Baker

UNLV Theses, Dissertations, Professional Papers, and Capstones

This study employs the three-dimensional visualization capability of cone-beam computed tomography (CBCT) to investigate the relationship between chronological age and timing of fusion of the spheno-occipital synchondrosis in a male/female subadult Hispanic population of Southern Nevada. The sample includes cross-sectional data of 374 orthodontic patients (166 males and 208 females) aged 8-20 years. The SOS is scored by a four-stage scoring system as completely open (stage 0), less than half fused (stage 1), more than half fused (stage 2), or completely fused (stage 3) as visualized in the midsagittal plane in the CBCT image. The relationship between SOS fusion stage …


College Student Depression: An Examination Of Cardiorespiratory Fitness, Gender And Sexual Orientation Diversity, And Help-Seeking Willingness, Sharon Jalene May 2019

College Student Depression: An Examination Of Cardiorespiratory Fitness, Gender And Sexual Orientation Diversity, And Help-Seeking Willingness, Sharon Jalene

UNLV Theses, Dissertations, Professional Papers, and Capstones

Depression is a serious illness characterized by persistent low mood, reduced cognitive capacity, and fatigue. Although treatable, depression is the leading cause of disability and ill-health worldwide and a significant contributor to suicide, the second leading cause of death for young Americans. In any given two-week period, 8.1% of adults in the United States had moderate to severe depression (2013-2016). The rate of depression for females was twice that of males and compared to the majority, sexual and gender minorities (SGM) were at a threefold risk. Furthermore, evidence suggests that depression incidence is three times higher in college students than …


From Deviant Symbol To Cultural Icon? Understanding Pit Bull Stigma, Genevieve Minter May 2019

From Deviant Symbol To Cultural Icon? Understanding Pit Bull Stigma, Genevieve Minter

UNLV Theses, Dissertations, Professional Papers, and Capstones

This research draws from twelve months of ethnographic data using Las Vegas as a case study to understand how pit bull owners experience and negotiate stigma in various social settings. The human-dog relationship, long rooted in utility, transformed in the modern era as animals were promoted from worker to companion. The world’s first dog register, The American Kennel Club, created breed standards and encouraged selective breeding, which influenced the idea of certain dogs being more physically “dangerous” than others. Though the pit bull is not the first dog “breed” to be the object of discrimination, it is the first dog …


Money Matters: Exploring The Financial Resources For Sports Medicine Programs In Public And Private Secondary Schools--A Qualitative Study, Natalie Mercedes Aviles Flores May 2018

Money Matters: Exploring The Financial Resources For Sports Medicine Programs In Public And Private Secondary Schools--A Qualitative Study, Natalie Mercedes Aviles Flores

UNLV Theses, Dissertations, Professional Papers, and Capstones

Context: Institutional funding and strained school budgets are a barrier to placing certified athletic trainers (ATCs) in secondary schools. The size and location of a school appear to be coinciding limitations (Mazerolle et al, 2015), but what is lacking in the literature is an

evaluation of how schools manage to provide adequate medical coverage. Resources are available, but there is question as to whether these schools consider or even utilize them.

Objective: The aim of this qualitative study is to explore the funding techniques and budget sources of high school athletic training clinics from the perspective of both private and …


Acute Salivary Steroid Hormone Responses During Coalitional And Dyadic Competitions In Hong Kong Juvenile Children, Timothy Mchale Dec 2017

Acute Salivary Steroid Hormone Responses During Coalitional And Dyadic Competitions In Hong Kong Juvenile Children, Timothy Mchale

UNLV Theses, Dissertations, Professional Papers, and Capstones

A large body of research links testosterone and cortisol responses to competition during adulthood. Little psychoneuroendocrine research has explored salivary steroid hormone responses to competition during middle childhood. This project investigated the relationship between acute salivary steroid hormone change, performance, competitor type, and outcome effects in three different field studies, while controlling for Body Mass Index (BMI) and pubertal development, in a population of ethnically Chinese, Hong Kong juvenile children, 8-11 years of age. The relative dynamics of salivary steroid change were assessed during a 1) coalitional physical competition (soccer) in boys, 2) a non-physical mixed-sex coalitional competition (math contest), …


Dietary Intake And Energy Expenditure Of Pararescuemen During Routine Training, Andrea Woita Dec 2017

Dietary Intake And Energy Expenditure Of Pararescuemen During Routine Training, Andrea Woita

UNLV Theses, Dissertations, Professional Papers, and Capstones

Pararescuemen are one group of Air Force Special Operations Forces (SOF) who engage in vigorous physical training to achieve mission readiness. This type of training requires high energy expenditures and matching dietary intake to support basic physiological needs and to meet performance demands. However, few studies have investigated the energy expenditure and dietary intake of SOF and none have specifically examined these behaviors in Pararescuemen. The goal of this investigation was to determine the energy expenditure and dietary intake of Pararescuemen during routine training - a period when these operators receive supervision and guidance for performance improvements, recovery, and career …


The Psychophysiological Correlates Of Personality, Trauma, Posttraumatic Stress Disorder And Social Support, Meghan E. Pierce May 2017

The Psychophysiological Correlates Of Personality, Trauma, Posttraumatic Stress Disorder And Social Support, Meghan E. Pierce

UNLV Theses, Dissertations, Professional Papers, and Capstones

Theories considering the etiology of psychopathy suggest that trauma exposure, specifically childhood maltreatment and sexual abuse, is related to the development of callous-unemotional traits in children and adolescents, which are precursors to psychopathic traits in adulthood. Furthermore, posttraumatic stress disorder has an opposite relationship with many of the emotional and behavioral components of the two-factor model of psychopathy. Specifically, PTSD is positively associated to IA and traits associated with it and negatively associated with FD. Thus, this study sought to expand upon the current theories of a trauma-based etiology of psychopathy by investigating the relationship between trauma, PTSD, and psychopathic …


Neural Processes Underlying Auditory Context Effects, Breanne Yerkes May 2017

Neural Processes Underlying Auditory Context Effects, Breanne Yerkes

UNLV Theses, Dissertations, Professional Papers, and Capstones

Auditory information within our natural environments is disorganized and often ambiguous, leaving our auditory systems with a complex task: organizing sound into coherent objects. The auditory system uses both current and prior information to assist in completing this task. The influences of previous context on current perception have been referred to as context effects. A contrastive context effect results in a current perception that is opposite of what is expected based on the physical stimulus properties presented during an immediate context. A facilitative context effect results in a current perception that is the same as the perception during the immediate …


Aging And Fermentation As Adaptive Food Management Strategies In The Arctic, Celeste Giordano May 2017

Aging And Fermentation As Adaptive Food Management Strategies In The Arctic, Celeste Giordano

UNLV Theses, Dissertations, Professional Papers, and Capstones

This dissertation is composed of three papers: one published article, one article under review for publication, and one published commentary. Chapter 1 provides an introduction to the dissertation as a whole – a work that investigates food aging and fermentation techniques in an indigenous Yup’ik Alaskan community, proposes an adaptive explanation for these strategies in the circumpolar north, and explores the potential importance of them cross-culturally and evolutionarily. Chapter 2 is a paper that describes the seal poke storage system – an indigenous food preservation and storage technique that Yup’ik Alaskans used to manage food security up until approximately one …


Behavioral Reactions To Emotional And Physical Infidelity: An Evolutionary Perspective, Mandy Walsh Walsh Dec 2016

Behavioral Reactions To Emotional And Physical Infidelity: An Evolutionary Perspective, Mandy Walsh Walsh

UNLV Theses, Dissertations, Professional Papers, and Capstones

This thesis examined the effects of sex and type of partner infidelity, including both physical (i.e., sexually involved with another person) and emotional (i.e., emotionally involved with another person) infidelity, on mate abandonment behaviors. Previous research has demonstrated sex differences in emotional responses to infidelity, where men react more negatively to physical infidelity and women react more negatively to emotional infidelity. While various studies have investigated perceived behavioral reactions using imagined scenarios, this study expands current research by utilizing actual retrospective reports. It was hypothesized that males would engage in significantly more mate abandonment behaviors after experiencing a physical infidelity, …


Sexual Determination From Frontal Sinus Analysis In A Subadult Population Using Archival Radiographic Records, Erica Crosta Dec 2016

Sexual Determination From Frontal Sinus Analysis In A Subadult Population Using Archival Radiographic Records, Erica Crosta

UNLV Theses, Dissertations, Professional Papers, and Capstones

The goal of this study is to use the improved imaging capability of cone-beam computerized tomography (CBCT) to investigate the development and sexual dimorphism of the frontal sinus and surrounding supraorbital region in the subadult population of urban Southern Nevada. CBCT radiographs were obtained from the UNLV School of Dental Medicine archival dental records. Five hundred and fifty six of these radiographs were reviewed for the study. Two hundred and sixteen patients (92 males, 124 females) between the ages of 7 and 20 years were included based on inclusion/exclusion criteria. Samples were categorized into 3 subadult age groups for analysis: …


Assessing Clinical Significance Of The Immediate Post-Concussion Assessment And Cognitive Testing Battery When Comparing Adjusted And Unadjusted Rci Methods For Different Ranges Of Baseline Scores, Ashley N. Figaro May 2016

Assessing Clinical Significance Of The Immediate Post-Concussion Assessment And Cognitive Testing Battery When Comparing Adjusted And Unadjusted Rci Methods For Different Ranges Of Baseline Scores, Ashley N. Figaro

UNLV Theses, Dissertations, Professional Papers, and Capstones

The growing concern revolving around the dangers of sports-related concussions have led to the most recent implementation of neurocognitive (NC) test batteries as a means to objectively determine the presence of a cognitive defect. Whereas any other sports-related injury can be diagnosed with tools such as an x-ray or MRI, a concussion represents a metabolic disturbance that cannot be identified by these diagnostic tools. Many neurocognitive test batteries employ statistical techniques to derive cut off scores in order to represent significant or insignificant changes as compared to individual baseline scores, or pre-established normative values. If an individuals’ post-injury score exceeds …


Scardovia Wiggsiae Prevalence In Orthodontic Patients, Brandon Joseph Streiff Dec 2015

Scardovia Wiggsiae Prevalence In Orthodontic Patients, Brandon Joseph Streiff

UNLV Theses, Dissertations, Professional Papers, and Capstones

Dental caries has mainly been associated with Streptococcus, Lactobacillus, Actinomyces and Veillonella species. But in recent salivary studies a new cariogenic pathogen, has been identified. This new bacteria, Scardovia wiggsiae (SW), is currently being tested within the UNLV School of Dental Medicine patient population. Although these current studies are being conducted to study its prevalence in both pediatric and adult populations, it has not been evaluated among patients with an altered oral environment as seen in patients with orthodontic appliances. Fixed orthodontic appliances increase the difficulty of removing daily plaque on and in between the teeth with standard oral hygiene …


Television Consumption And Child Obesity: Linking Children's Contemporary Television Use, Physical Activity, And Advertising To Putnam's Displacement Hypothesis, Brittany L. Altamirano Dec 2015

Television Consumption And Child Obesity: Linking Children's Contemporary Television Use, Physical Activity, And Advertising To Putnam's Displacement Hypothesis, Brittany L. Altamirano

UNLV Theses, Dissertations, Professional Papers, and Capstones

This study observed the relationship between television consumption and child obesity through the theoretical construct of Putnam’s displacement hypothesis. It did so by updating the previous research through the investigation of the displacement of both physical activity and advertisements on contemporary television platforms. The inclusion of Putnam’s displacement hypothesis was to provide a foundational framework, not found in previous literature, to study two important paradigms that were represented in previous research: 1) the displacement of physical activity; and 2) the displacement of traditional advertisement exposure.

Several trends became apparent within previous literature. Previous literature did not include an explicitly stated …


The Effect Of Sleep On Perceptual Learning And Memory Consolidation, Vanessa Claire Irsik Aug 2015

The Effect Of Sleep On Perceptual Learning And Memory Consolidation, Vanessa Claire Irsik

UNLV Theses, Dissertations, Professional Papers, and Capstones

An ability to segregate speech accurately is essential given that most auditory environments contain other overlapping conversations or environmental noise. While perceiving speech among background noise can be difficult in and of itself, those with hearing impairments can experience considerable difficulty. While training has been shown to benefit perceptual segregation of trained sounds, it is unclear how such training transfers to sounds not included in a training regimen. The current study aimed to address this question by training listeners on a portion of sounds during a vowel segregation task, and subsequently testing on both the trained sounds and untrained sounds. …


Comparing Functional Motor Control And Gait Parameters In Children With Autism To Those Of Age-Matched Peers Who Are Typically Developing, Patricia Stevenson, Samantha Novotny, Jillian May, Christopher Ancell May 2015

Comparing Functional Motor Control And Gait Parameters In Children With Autism To Those Of Age-Matched Peers Who Are Typically Developing, Patricia Stevenson, Samantha Novotny, Jillian May, Christopher Ancell

UNLV Theses, Dissertations, Professional Papers, and Capstones

The purpose of this study was to compare motor performance of children with Autism Spectrum Disorder (ASD) to that of age-matched peers who are typically developing (TD) on motor control tasks plus symmetry and variability of gait parameters across four walking conditions. A sample of convenience of children with ASD (n=6) and peers who are TD (n=6) were recruited. Motor control was assessed using initiation and completion times on the Timed Up and Go (TUG) test. Gait parameters were collected using a computerized walkway under four trial conditions: 1) walking at self-selected velocity (SSV); 2) walking during a tray-carrying task …


Functional Capacity In Schizophrenia: Relationship Among Effort, Reinforcement Learning And Self-Beliefs, Sally J. Vogel May 2015

Functional Capacity In Schizophrenia: Relationship Among Effort, Reinforcement Learning And Self-Beliefs, Sally J. Vogel

UNLV Theses, Dissertations, Professional Papers, and Capstones

Individuals with schizophrenia exhibit a wide range of complex neurocognitive, psychiatric and behavioral impairments. Recent research suggests that this complex array of symptoms can be at least partially accounted for by dysfunction in more basic mechanisms, such as the ability to learn from positive and negative reinforcement, or the ability to exert adequate effort when completing simple tasks. Evidence also suggests that deficits in these basic mechanisms may contribute to more complex symptoms, such as functional impairment. Also, the relationship between neurocognitive deficits and functional impairment has been found to be mediated by defeatist performance beliefs. However, studies have not …


A Comparison Of The Effects Of Different Doses Of Gabab Receptor Ligands On Spatial Learning And Memory And Memory Flexibility, Chelcie Heaney May 2015

A Comparison Of The Effects Of Different Doses Of Gabab Receptor Ligands On Spatial Learning And Memory And Memory Flexibility, Chelcie Heaney

UNLV Theses, Dissertations, Professional Papers, and Capstones

The principal inhibitory neurotransmitter in the brain, gamma amino-butyric acid (GABA), mediates several types of learning and memory. Of the two main receptor subtypes for GABA, the in vivo role of GABAB receptor in learning and memory is less well characterized and the current data often conflict. Based on the current literature, it is unclear, for instance, whether enhancing GABAergic activity via the GABAB receptor could be beneficial for or detrimental to learning and memory. Hippocampally-dependent learning and memory tasks are of particular interest due to their clinical relevance to patients with schizophrenia or Alzheimer’s disease, who exhibit impaired performance …