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Full-Text Articles in Life Sciences

Methanogens, Plausible Extraterrestrial Life Forms On Mars, And Their Tolerance To Increasing Concentrations Of Illite Clay, Chandler Kern Dec 2018

Methanogens, Plausible Extraterrestrial Life Forms On Mars, And Their Tolerance To Increasing Concentrations Of Illite Clay, Chandler Kern

Biological Sciences Undergraduate Honors Theses

Methanogens, some of Earth’s most primitive prokaryotic organisms, are candidates for possible life forms capable of inhabiting Mars. Specifically, four different species (Methanobacterium formicicum, Methanococcus maripaludis, Methanosarcina barkeri, Methanothermobacter wolfeii) were analyzed for their tolerance to the presence of illite clay. Illite is a crystalline mineral that has been identified from regions of Mars’s surface. Results indicated that all four species grew with some success in the illite at different concentrations. This experimentation with methanogens’ abilities to survive and reproduce in the presence of illite allows for a more accurate understanding of the potential capability of microbial growth ...


Diversity And Inclusion In The Science Classroom, Sowmya Anjur Nov 2018

Diversity And Inclusion In The Science Classroom, Sowmya Anjur

Faculty Publications & Research

A Diversity, Epidemiology and social justice unit was incorporated into the Physiology and Disease curriculum in Fall 2016. Students discussed topics such as social and cultural influences on diversity thinking, and selective treatment in hospitals based on race. It was very noteworthy that students were united in their thinking regarding diversity and inclusion, despite the fact that they were from different backgrounds and diverse cultures. In 2017, additional discussions were held on equity in education. Students who were otherwise reserved were encouraged enough to express their views, and everyone appreciated the fact that they had been included.


Modeling In The Physiology Classroom, Sowmya Anjur Nov 2018

Modeling In The Physiology Classroom, Sowmya Anjur

Faculty Publications & Research

Physiology and Disease is a Biology elective at IMSA that has been developed to be mostly student-centered. Some examples of student projects include modeling heart structure to reflect function and creating LED arduino monitors to measure heart rate. Students also measure their lung capacity and blood pressure to demonstrate correlation of these values with heart rate, and trace the correlation back to neuronal controls. Projects such as these integrate other disciplines such as engineering and conform to NGSS Science and Engineering standards and NGSS Cross cutting Concepts standards. Students take responsibility for their own learning and articulate better on tests.


Activation Of The Apoptotic Pathway During Prolonged Prometaphase Blocks Daughter Cell Proliferation, Yumi Uetake, Greenfield Sluder Nov 2018

Activation Of The Apoptotic Pathway During Prolonged Prometaphase Blocks Daughter Cell Proliferation, Yumi Uetake, Greenfield Sluder

Radiology Publications and Presentations

When untransformed human cells spend >1.5 hr. in prometaphase under standard culture conditions, all daughters arrest in G1 despite normal division of their mothers. We investigate what happens during prolonged prometaphase that leads to daughter cell arrest in the absence of DNA damage. We find that progressive loss of anti-apoptotic MCL-1 activity and oxidative stress act in concert to partially activate the apoptosis pathway resulting in the delayed death of some daughters and senescence for the rest. At physiological oxygen levels, longer prometaphase durations are needed for all daughters to arrest. Partial activation of apoptosis during prolonged prometaphase leads ...


Emerging Roles Of The Membrane Potential: Action Beyond The Action Potential, Lina Abdul Kadir, Michael Stacey, Richard Barrett-Jolley Nov 2018

Emerging Roles Of The Membrane Potential: Action Beyond The Action Potential, Lina Abdul Kadir, Michael Stacey, Richard Barrett-Jolley

Bioelectrics Publications

Whilst the phenomenon of an electrical resting membrane potential (RMP) is a central tenet of biology, it is nearly always discussed as a phenomenon that facilitates the propagation of action potentials in excitable tissue, muscle, and nerve. However, as ion channel research shifts beyond these tissues, it became clear that the RMP is a feature of virtually all cells studied. The RMP is maintained by the cell's compliment of ion channels. Transcriptome sequencing is increasingly revealing that equally rich compliments of ion channels exist in both excitable and non-excitable tissue. In this review, we discuss a range of critical ...


Reduced Gut Microbiome Protects From Alcohol-Induced Neuroinflammation And Alters Intestinal And Brain Inflammasome Expression, Patrick P. Lowe, Benedek Gyongyosi, Abhishek Satishchandran, Arvin Iracheta-Vellve, Yeonhee Cho, Aditya Ambade, Gyongyi Szabo Oct 2018

Reduced Gut Microbiome Protects From Alcohol-Induced Neuroinflammation And Alters Intestinal And Brain Inflammasome Expression, Patrick P. Lowe, Benedek Gyongyosi, Abhishek Satishchandran, Arvin Iracheta-Vellve, Yeonhee Cho, Aditya Ambade, Gyongyi Szabo

Open Access Articles

BACKGROUND: The end-organ effects of alcohol span throughout the entire body, from the gastrointestinal tract to the central nervous system (CNS). In the intestine, alcohol use changes the microbiome composition and increases gut permeability allowing translocation of microbial components into the circulation. Gut-derived pathogen-associated signals initiate inflammatory responses in the liver and possibly elsewhere in the body. Because previous studies showed that the gut microbiome contributes to alcohol-induced liver disease, we hypothesized that antibiotic administration to reduce the gut microbiome would attenuate alcohol-induced inflammation in the brain and small intestine (SI).

METHODS: Six- to 8-week-old C57BL/6J female mice were ...


In The Office, Theo Heilman '19, Nathan Lee '19, Prachi Patil '19, Katie Si '19 Oct 2018

In The Office, Theo Heilman '19, Nathan Lee '19, Prachi Patil '19, Katie Si '19

Human Diseases Graphic Novels

No abstract provided.


Diseases At Work, Alice Liu '19, Nicholas Opiola '19, Gunnar Bergmann '19, Femi Durodola '20, Suraj Sunkara '19 Oct 2018

Diseases At Work, Alice Liu '19, Nicholas Opiola '19, Gunnar Bergmann '19, Femi Durodola '20, Suraj Sunkara '19

Human Diseases Graphic Novels

No abstract provided.


Kidney Stones, Bopo Taiwo '20, Ishanpepe Jagusah '20 Oct 2018

Kidney Stones, Bopo Taiwo '20, Ishanpepe Jagusah '20

Human Diseases Graphic Novels

No abstract provided.


A Day In The Life, Amit Somalwar '19, Daniel Chen '19 Oct 2018

A Day In The Life, Amit Somalwar '19, Daniel Chen '19

Human Diseases Graphic Novels

No abstract provided.


The Assassin Bug, Lola Alao '20, Harsha Nalam '19, Dwanne Colobong '19, Trisha Sudhakar '19 Oct 2018

The Assassin Bug, Lola Alao '20, Harsha Nalam '19, Dwanne Colobong '19, Trisha Sudhakar '19

Human Diseases Graphic Novels

No abstract provided.


The Blue Baby, Lola Alao, Harsha Nalam '19, Dwanne Colobong '19, Trisha Sudhakar '19 Oct 2018

The Blue Baby, Lola Alao, Harsha Nalam '19, Dwanne Colobong '19, Trisha Sudhakar '19

Human Diseases Graphic Novels

No abstract provided.


Modified Cantilever Arrays Improve Sensitivity And Reproducibility Of Nanomechanical Sensing In Living Cells, Samadhan B. Patil, Rajai M. Al-Jehani, Hashem Etayash, Valerian Turbe, Keren Jiang, Joe Bailey, Walid Al-Akkad, Rania Soudy, Kamaljit Kaur, Rachel A. Mckendry, Thomas Thundat, Joseph W. Ndieyira Oct 2018

Modified Cantilever Arrays Improve Sensitivity And Reproducibility Of Nanomechanical Sensing In Living Cells, Samadhan B. Patil, Rajai M. Al-Jehani, Hashem Etayash, Valerian Turbe, Keren Jiang, Joe Bailey, Walid Al-Akkad, Rania Soudy, Kamaljit Kaur, Rachel A. Mckendry, Thomas Thundat, Joseph W. Ndieyira

Pharmacy Faculty Articles and Research

Mechanical signaling involved in molecular interactions lies at the heart of materials science and biological systems, but the mechanisms involved are poorly understood. Here we use nanomechanical sensors and intact human cells to provide unique insights into the signaling pathways of connectivity networks, which deliver the ability to probe cells to produce biologically relevant, quantifiable and reproducible signals. We quantify the mechanical signals from malignant cancer cells, with 10 cells per ml in 1000-fold excess of non-neoplastic human epithelial cells. Moreover, we demonstrate that a direct link between cells and molecules creates a continuous connectivity which acts like a percolating ...


Cardiodynamic Associations With Resilience In Undergraduate Students And The Effect Of A Mentorship Intervention, Rachel J. Knetsch Oct 2018

Cardiodynamic Associations With Resilience In Undergraduate Students And The Effect Of A Mentorship Intervention, Rachel J. Knetsch

Electronic Thesis and Dissertation Repository

The National College Health Assessment (NCHA) indicates that a majority of Canadian university students report feeling overwhelmed, stressed, and anxious during their undergraduate studies. Resilience refers to positive adaptation, or the ability to maintain or regain mental health, despite experiencing adversity (Herrman et al., 2011). While autonomic indices have been used to describe chronic physiological stress, the role of heart rate variability (HRV) as an index of resilience remains unclear. This research tested the hypotheses that (1) there is a relationship between HRV and resilience scoresand (2) a mentorship intervention will improve HRV and resilience outcomes. Fifty-seven first year students ...


2018 Lifesaving Foundation Projects, Lifesaving Foundation Oct 2018

2018 Lifesaving Foundation Projects, Lifesaving Foundation

International Journal of Aquatic Research and Education

No abstract provided.


The Ireland Medal Recipients 2003-2017, Lifesaving Foundation Oct 2018

The Ireland Medal Recipients 2003-2017, Lifesaving Foundation

International Journal of Aquatic Research and Education

No abstract provided.


Back Cover, Lifesaving Foundation Oct 2018

Back Cover, Lifesaving Foundation

International Journal of Aquatic Research and Education

No abstract provided.


Understanding The Role Of The Personal Floatation Device: Workshop, Patrick Buck Ph.D., Remt Oct 2018

Understanding The Role Of The Personal Floatation Device: Workshop, Patrick Buck Ph.D., Remt

International Journal of Aquatic Research and Education

No abstract provided.


Wearing Life Jackets While Swimming In Open Water, Elizabeth "Tizzy" Bennett, Linda Quan Md Oct 2018

Wearing Life Jackets While Swimming In Open Water, Elizabeth "Tizzy" Bennett, Linda Quan Md

International Journal of Aquatic Research and Education

No abstract provided.


Narratives Of Drowning - Exploring Family And Community Resilience, John S.G. Wells Ph.D., M. Bergin, John Connolly, S. Denieffe Oct 2018

Narratives Of Drowning - Exploring Family And Community Resilience, John S.G. Wells Ph.D., M. Bergin, John Connolly, S. Denieffe

International Journal of Aquatic Research and Education

No abstract provided.


Are My Children As Safe In Open Water As I Think They Are?, Shayne Baker D. Prof. Oct 2018

Are My Children As Safe In Open Water As I Think They Are?, Shayne Baker D. Prof.

International Journal of Aquatic Research and Education

No abstract provided.


The Lifesaving Foundation Library Collection, Kieran Cronin Ba, Mals Oct 2018

The Lifesaving Foundation Library Collection, Kieran Cronin Ba, Mals

International Journal of Aquatic Research and Education

No abstract provided.


Is There A Crisis In The Aquatic Profession?, Robert Keig Stallman Ph.D. Oct 2018

Is There A Crisis In The Aquatic Profession?, Robert Keig Stallman Ph.D.

International Journal of Aquatic Research and Education

No abstract provided.


The Assessment Of Swimming And Survival Skills: Is Your Programme Fit For These Purposes?, Paolo Di Paola Ba Oct 2018

The Assessment Of Swimming And Survival Skills: Is Your Programme Fit For These Purposes?, Paolo Di Paola Ba

International Journal of Aquatic Research and Education

No abstract provided.


Investigating Drowning Deaths In The United Kingdom, Paul Anderson Chief Superintendent Oct 2018

Investigating Drowning Deaths In The United Kingdom, Paul Anderson Chief Superintendent

International Journal of Aquatic Research and Education

No abstract provided.


In Extreme Open Water Swims: Why Understanding The Challenge Is As Important As Training For The Distance, Nuala Moore Oct 2018

In Extreme Open Water Swims: Why Understanding The Challenge Is As Important As Training For The Distance, Nuala Moore

International Journal of Aquatic Research and Education

No abstract provided.


Predicting The Magnitude And Duration Of The Life-Threatening Cold Shock Response On Accidental Immersion: Estimating The Risk Of Drowning, Martin Barwood Ph.D. Oct 2018

Predicting The Magnitude And Duration Of The Life-Threatening Cold Shock Response On Accidental Immersion: Estimating The Risk Of Drowning, Martin Barwood Ph.D.

International Journal of Aquatic Research and Education

No abstract provided.


Rnli: ‘Respect The Water’ Campaign – Putting Prevention First, Ross Macleod Ba Oct 2018

Rnli: ‘Respect The Water’ Campaign – Putting Prevention First, Ross Macleod Ba

International Journal of Aquatic Research and Education

No abstract provided.


Effective Water Competence Training For School-Aged Children: Teaching Strategies For Skills, Knowledge, And Attitudes, Kristine De Martelaer Ph.D., E. D'Hondt, J. Van Driel, F. Bardid, Joost J.L.M. Bierens Md, Ph.D., Professor Oct 2018

Effective Water Competence Training For School-Aged Children: Teaching Strategies For Skills, Knowledge, And Attitudes, Kristine De Martelaer Ph.D., E. D'Hondt, J. Van Driel, F. Bardid, Joost J.L.M. Bierens Md, Ph.D., Professor

International Journal of Aquatic Research and Education

No abstract provided.


A Mother’S Perspective: ‘River And Sea Sense’, Debbie Anne Turnbull Oct 2018

A Mother’S Perspective: ‘River And Sea Sense’, Debbie Anne Turnbull

International Journal of Aquatic Research and Education

No abstract provided.